Dr. Dean Ornish: Your genes are not your fate

Translator: Janja Sterle Reviewer: Nina Jere

One way to change our genes is to make new ones,

Gene lahko spremenite tako, da naredite nove,

as Craig Venter has so elegantly shown.

kot nam je to lepo razložil Craig Venter.

Another is to change our lifestyles.

Lahko pa spremenite svoj življenjski slog.

And what we're learning is how powerful and dynamic these changes can be,

Odkrivamo, da so te spremembe res močne in silovite.

that you don't have to wait very long to see the benefits.

Koristi se hitro pokažejo.

When you eat healthier, manage stress, exercise and love more,

Z zdravo prehrano, manj stresa, več telovadbe in ljubezni

your brain actually gets more blood flow and more oxygen.

možgani dobijo več krvi in več kisika.

But more than that, your brain gets measurably bigger.

Poleg tega se možgani opazno povečajo.

Things that were thought impossible just a few years ago

Stvari, ki so se zdele nemogoče pred nekaj leti,

can actually be measured now.

lahko zdaj izmerimo.

This was figured out by Robin Williams

To je nekaj let pred nami

a few years before the rest of us.

ugotovil Robin Williams [v filmu Ga. Doubtfire].

Now, there's some things that you can do

Možganom lahko na več načinov pomagamo

to make your brain grow new brain cells.

ustvariti nove možganske celice.

Some of my favorite things, like chocolate and tea, blueberries,

Najraje imam čokolado, čaj, borovnice.

alcohol in moderation, stress management

Drugi dejavniki so alkohol v zmernih količinah, obvladovanje stresa

and cannabinoids found in marijuana.

in kanabinoidi v marihuani.

I'm just the messenger.

Samo podajam dognanja drugih.

(Laughter)

(smeh)

What were we just talking about?

O čem sem že govoril?

(Laughter)

(smeh)

And other things that can make it worse,

Poglejmo stvari, ki so za možgane slabe,

that can cause you to lose brain cells.

ki zmanjšujejo število možganskih celic.

The usual suspects, like saturated fat and sugar,

Znane razvade, denimo nasičene maščobe in sladkor,

nicotine, opiates, cocaine, too much alcohol and chronic stress.

nikotin, opiati, kokain, preveč alkohola in kroničen stres.

Your skin gets more blood flow when you change your lifestyle,

Z zdravim načinom življenja bo koža bolj prekrvavljena.

so you age less quickly. Your skin doesn't wrinkle as much.

Starali se boste se počasneje, gub bo manj.

Your heart gets more blood flow.

Prekrvavitev srca se bo izboljšala.

We've shown that you can actually reverse heart disease.

Lahko se izognete srčnim boleznim.

That these clogged arteries that you see on the upper left,

Zamašene arterije, ki jih vidite zgoraj levo,

after only a year become measurably less clogged.

so po samo enem letu postale bolj prehodne.

And the cardiac PET scan shown on the lower left,

To je pozitronska tomografija srca.

the blue means no blood flow.

Modra barva pomeni brez pretoka krvi.

A year later -- orange and white is maximum blood flow.

Po enem letu: oranžna in bela pomenita največji pretok krvi.

We've shown you may be able to stop and reverse the progression

Dokazali smo, da lahko ustavimo in deloma ozdravimo

of early prostate cancer and, by extension, breast cancer,

raka na prostati in raka na dojkah v začetni fazi, če uvedemo te spremembe.

simply by making these changes.

raka na prostati in raka na dojkah v začetni fazi, če uvedemo te spremembe.

We've found that tumor growth in vitro was inhibited

S poskusi na celicah smo dokazali, da se je rast tumorja

70 percent in the group that made these changes,

ustavila pri 70% ljudi, ki so spremenili življenje.

whereas only nine percent in the comparison group.

V kontrolni skupini je bil delež samo 9 %.

These differences were highly significant.

Te razlike so neverjetne.

Even your sexual organs get more blood flow,

Tudi spolni organi so bolj prekrvavljeni,

so you increase sexual potency.

kar krepi spolno potenco.

One of the most effective anti-smoking ads was done

Najboljšo protikadilsko kampanjo je pripravilo

by the Department of Health Services,

ameriško ministrstvo za zdravstvo.

showing that nicotine, which constricts your arteries,

Objavili so podatek, da nikotin skrči arterije,

can cause a heart attack or a stroke,

kar lahko povzroči srčno kap ali infarkt,

but it also causes impotence.

povzroča pa tudi impotenco.

Half of guys who smoke are impotent.

Polovica moških kadilcev je impotentna.

How sexy is that?

Se vam zdi to seksi?

Now we're also about to publish a study --

Naša nova raziskava kaže,

the first study showing you can change gene expression in men with prostate cancer.

da lahko spremenimo genski izraz pri moških z rakom na prostati.

This is what's called a heat map --

To je toplotni zemljevid.

and the different colors -- and along the side, on the right, are different genes.

Različne barve predstavljajo različne gene.

And we found that over 500 genes were favorably changed --

Odkrili smo, da se je 500 genov spremenilo na bolje.

in effect, turning on the good genes, the disease-preventing genes,

Vklopijo se dobri geni, ki preprečujejo bolezni,

turning off the disease-promoting genes.

in izklopijo geni, ki povečujejo možnost bolezni.

And so these findings I think are really very powerful,

Ti rezultati so zelo pomembni.

giving many people new hope and new choices.

Ljudem ponujajo novo upanje in nove možnosti.

And companies like Navigenics and DNA Direct and 23andMe,

Podjetja, kot so Navigenix, DNA Direct in 23andMe,

that are giving you your genetic profiles,

vam lahko izdelajo genetski profil.

are giving some people a sense of, "Gosh, well, what can I do about it?"

Ljudje se potem vprašajo – kaj lahko sploh še naredim?

Well, our genes are not our fate, and if we make these changes --

Naši geni niso naša usoda. S spremembo življenja ...

they're a predisposition -- but if we make bigger changes

Geni so le nagnjenost in če naredimo večje spremembe, kot bi jih sicer,

than we might have made otherwise,

Geni so le nagnjenost in če naredimo večje spremembe, kot bi jih sicer,

we can actually change how our genes are expressed.

lahko spremenimo izražanje naših genov.

Thank you.

Hvala.

(Applause)

(aplavz)