Dr. Dean Ornish: Your genes are not your fate

88,432 views ใƒป 2014-04-24

TED


ืื ื ืœื—ืฅ ืคืขืžื™ื™ื ืขืœ ื”ื›ืชื•ื‘ื™ื•ืช ื‘ืื ื’ืœื™ืช ืœืžื˜ื” ื›ื“ื™ ืœื”ืคืขื™ืœ ืืช ื”ืกืจื˜ื•ืŸ.

ืžืชืจื’ื: Yifat Adler ืžื‘ืงืจ: Sigal Tifferet
00:12
One way to change our genes is to make new ones,
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ื“ืจืš ืื—ืช ืœืฉื ื•ืช ืืช ื”ื’ื ื™ื ืฉืœื ื• ื”ื™ื ืœื™ื™ืฆืจ ื’ื ื™ื ื—ื“ืฉื™ื,
00:14
as Craig Venter has so elegantly shown.
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ื›ืคื™ ืฉืงืจื™ื™ื’ ื•ื ื˜ืจ ื”ื•ื›ื™ื— ื‘ืืœื’ื ื˜ื™ื•ืช ืจื‘ื”.
00:16
Another is to change our lifestyles.
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ืœื—ื™ืœื•ืคื™ืŸ, ืืคืฉืจ ืœืฉื ื•ืช ืืช ืื•ืจื— ื”ื—ื™ื™ื ืฉืœื ื•.
00:19
And what we're learning is how powerful and dynamic these changes can be,
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ืื ื• ืœื•ืžื“ื™ื ืฉืฉื™ื ื•ื™ื™ื ืืœื” ื™ื›ื•ืœื™ื ืœื”ื™ื•ืช ืจื‘ื™-ืขื•ืฆืžื” ื•ื“ื™ื ืžื™ื™ื ืžืื“,
00:23
that you don't have to wait very long to see the benefits.
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ื•ืฉืื™ืŸ ืฆื•ืจืš ืœื”ืžืชื™ืŸ ื”ืจื‘ื” ื›ื“ื™ ืœื”ื‘ื—ื™ืŸ ื‘ืชื•ืขืœืช ืฉืœื”ื.
00:26
When you eat healthier, manage stress, exercise and love more,
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ื›ืฉืื•ื›ืœื™ื ื‘ืจื™ื ื™ื•ืชืจ, ืžื ื”ืœื™ื ืœื—ืฆื™ื, ืžืชืขืžืœื™ื ื•ืื•ื”ื‘ื™ื ื™ื•ืชืจ,
00:31
your brain actually gets more blood flow and more oxygen.
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ืืกืคืงืช ื”ื“ื ื•ื”ื—ืžืฆืŸ ืœืžื•ื— ื’ื“ืœื”.
00:33
But more than that, your brain gets measurably bigger.
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ืืš ืžืขื‘ืจ ืœื›ืš, ื”ืžื•ื— ื’ื“ืœ ื‘ืžื™ื“ื” ื ื™ื›ืจืช.
00:36
Things that were thought impossible just a few years ago
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ื“ื‘ืจื™ื ืฉื‘ืขื‘ืจ ื—ืฉื‘ื ื• ืœื‘ืœืชื™-ืืคืฉืจื™ื™ื
00:38
can actually be measured now.
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ื ื™ืชื ื™ื ื”ื™ื•ื ืœืžื“ื™ื“ื”.
00:40
This was figured out by Robin Williams
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ืจื•ื‘ื™ืŸ ื•ื•ื™ืœื™ืืžืก ื”ื‘ื™ืŸ ื–ืืช ื›ืžื” ืฉื ื™ื ืœืคื ื™ื ื• (ื‘"ื’ื‘ืจืช ื“ืื•ื˜ืคื™ื™ืจ").
00:43
a few years before the rest of us.
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(ืฆื—ื•ืง)
00:45
Now, there's some things that you can do
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ื ื™ืชืŸ ืœืขืฉื•ืช ืžืกืคืจ ื“ื‘ืจื™ื
00:47
to make your brain grow new brain cells.
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ื›ื“ื™ ืœื’ืจื•ื ืœืžื•ื— ืœื™ื™ืฆืจ ืชืื™ ืžื•ื— ื—ื“ืฉื™ื.
ื—ืœืง ืžื”ื“ื‘ืจื™ื ื”ืื”ื•ื‘ื™ื ืขืœื™, ื›ืžื• ืฉื•ืงื•ืœื“ ื•ืชื”, ืื•ื›ืžื ื™ื•ืช,
00:50
Some of my favorite things, like chocolate and tea, blueberries,
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00:52
alcohol in moderation, stress management
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ืืœื›ื•ื”ื•ืœ ื‘ืžื™ื“ื”, ื ื™ื”ื•ืœ ืœื—ืฆื™ื
00:56
and cannabinoids found in marijuana.
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ื•ืงื ื‘ื™ื ื•ืื™ื“ื™ื, ืฉื ืžืฆืื™ื ื‘ืžืจื™ื—ื•ืื ื”.
00:58
I'm just the messenger.
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ืื ื™ ืจืง ื”ืฉืœื™ื—.
01:01
(Laughter)
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(ืฆื—ื•ืง)
01:04
What were we just talking about?
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ืื™ืคื” ื”ื™ื™ื ื•?
01:07
(Laughter)
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(ืฆื—ื•ืง)
01:09
And other things that can make it worse,
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ื“ื‘ืจื™ื ืื—ืจื™ื ืขืœื•ืœื™ื ืœื”ื—ืจื™ืฃ ืืช ื”ืžืฆื‘ ื•ืœื’ืจื•ื ืœื”ืจืก ืชืื™ ืžื•ื—.
01:11
that can cause you to lose brain cells.
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01:13
The usual suspects, like saturated fat and sugar,
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ื”ื—ืฉื•ื“ื™ื ื”ืจื’ื™ืœื™ื, ื›ืžื• ืฉื•ืžืŸ ืจื•ื•ื™ ื•ืกื•ื›ืจ,
01:16
nicotine, opiates, cocaine, too much alcohol and chronic stress.
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ื ื™ืงื•ื˜ื™ืŸ, ืื•ืคื™ืื˜ื™ื, ืงื•ืงืื™ืŸ, ืขื•ื“ืฃ ืืœื›ื•ื”ื•ืœ ื•ืœื—ืฅ ื›ืจื•ื ื™.
01:20
Your skin gets more blood flow when you change your lifestyle,
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ื›ืฉืžืฉื ื™ื ืืช ืื•ืจื— ื”ื—ื™ื™ื, ืืกืคืงืช ื”ื“ื ืœืขื•ืจ ืžืฉืชืคืจืช
01:23
so you age less quickly. Your skin doesn't wrinkle as much.
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ื•ื›ืš ืžื–ื“ืงื ื™ื ืœืื˜ ื™ื•ืชืจ, ื”ืขื•ืจ ืœื ืžืชืงืžื˜ ื›ืœ-ื›ืš,
01:26
Your heart gets more blood flow.
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ื•ื”ืœื‘ ืžืงื‘ืœ ืืกืคืงืช ื“ื ืžืฉื•ืคืจืช.
01:28
We've shown that you can actually reverse heart disease.
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ื”ืจืื ื• ืฉื ื™ืชืŸ ืœืžืขืฉื” ืœื”ืคื•ืš ืืช ื›ื™ื•ื•ื ืŸ ืฉืœ ืžื—ืœื•ืช ืœื‘,
01:30
That these clogged arteries that you see on the upper left,
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ืฉื”ืขื•ืจืงื™ื ื”ืกืชื•ืžื™ื ืฉืจื•ืื™ื ืœืžืขืœื” ืžืฉืžืืœ,
01:33
after only a year become measurably less clogged.
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ื ืคืชื—ื™ื ื‘ืื•ืคืŸ ืžืฉืžืขื•ืชื™ ืื—ืจื™ ืฉื ื” ืื—ืช ื‘ืœื‘ื“.
01:35
And the cardiac PET scan shown on the lower left,
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ื‘ื˜ื•ืžื•ื’ืจืคื™ื™ืช ืคื•ื–ื™ื˜ืจื•ื ื™ื ืฉืœ ื”ืœื‘, ืœืžื˜ื” ืžืฉืžืืœ,
01:37
the blue means no blood flow.
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ื”ื›ื—ื•ืœ ืžืฆื™ื™ืŸ ื”ืขื“ืจ ื–ืจื™ืžืช ื“ื.
01:39
A year later -- orange and white is maximum blood flow.
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ืื—ืจื™ ืฉื ื” - ื”ื›ืชื•ื ื•ืœื‘ืŸ ืžืจืื™ื ื–ืจื™ืžืช ื“ื ืžื™ืจื‘ื™ืช.
01:42
We've shown you may be able to stop and reverse the progression
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ื”ื•ื›ื—ื ื• ืฉื ื™ืชืŸ ืœืขืฆื•ืจ ื•ืœื”ืคื•ืš ืืช ื”ืชืงื“ืžื•ืช
01:45
of early prostate cancer and, by extension, breast cancer,
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ืกืจื˜ืŸ ื”ืขืจืžื•ื ื™ืช ื•ืกืจื˜ืŸ ื”ืฉื“ ื‘ืฉืœื‘ื™ื”ื ื”ืžื•ืงื“ืžื™ื,
01:47
simply by making these changes.
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ืื ืคืฉื•ื˜ ืžื‘ืฆืขื™ื ืืช ื”ืฉื™ื ื•ื™ื™ื ื”ืืœื”.
01:49
We've found that tumor growth in vitro was inhibited
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ื”ืชืงื“ืžื•ืช ื”ื’ื™ื“ื•ืœ ื‘ืžื‘ื—ื ื” ื“ื•ื›ืื”
01:52
70 percent in the group that made these changes,
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ื‘-70% ื‘ืงื‘ื•ืฆื” ืฉื‘ื™ืฆืขื” ืฉื™ื ื•ื™ื™ื ืืœื”,
01:54
whereas only nine percent in the comparison group.
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ื•ืจืง ื‘-9% ื‘ืงื‘ื•ืฆืช ื”ื‘ื™ืงื•ืจืช.
01:57
These differences were highly significant.
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ืœื”ืคืจืฉื™ื ืืœื” ื™ืฉ ืจืžืช ืžื•ื‘ื”ืงื•ืช ื’ื‘ื•ื”ื”.
01:59
Even your sexual organs get more blood flow,
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ืืคื™ืœื• ืื‘ืจื™ ื”ืžื™ืŸ ืžืงื‘ืœื™ื ืืกืคืงืช ื“ื ืžืฉื•ืคืจืช,
02:01
so you increase sexual potency.
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ื•ื›ืš ืžื’ื‘ื™ืจื™ื ืืช ื”ืื•ืŸ ื”ืžื™ื ื™.
02:03
One of the most effective anti-smoking ads was done
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ืื—ืช ื”ืคืจืกื•ืžื•ืช ื”ื™ืขื™ืœื•ืช ื‘ื™ื•ืชืจ ื ื’ื“ ืขื™ืฉื•ืŸ
02:05
by the Department of Health Services,
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ืฉืœ ื”ืžื—ืœืงื” ืœืฉื™ืจื•ืชื™ ื”ื‘ืจื™ืื•ืช,
02:07
showing that nicotine, which constricts your arteries,
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ื”ืจืืชื” ืฉื ื™ืงื•ื˜ื™ืŸ, ืฉืžื›ื•ื•ืฅ ืืช ื”ืขื•ืจืงื™ื,
02:09
can cause a heart attack or a stroke,
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ืขืœื•ืœ ืœื’ืจื•ื ืœื”ืชืงืฃ ืœื‘ ืื• ืœืฉื‘ืฅ,
02:11
but it also causes impotence.
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ืื‘ืœ ื”ื•ื ื’ื•ืจื ื’ื ืœืื™ืžืคื•ื˜ื ืฆื™ื”.
02:13
Half of guys who smoke are impotent.
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ื—ืฆื™ ืžื”ื’ื‘ืจื™ื ืฉืžืขืฉื ื™ื ื”ื ืื™ืžืคื•ื˜ื ื˜ื™ื.
ื–ื” ืกืงืกื™?
02:15
How sexy is that?
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02:16
Now we're also about to publish a study --
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ื’ื™ืœื™ื ื• ื’ื ืฉืืคืฉืจ ืœืฉื ื•ืช
02:18
the first study showing you can change gene expression in men with prostate cancer.
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ื”ืชื‘ื˜ืื•ืช ื’ื ื˜ื™ืช ื‘ื’ื‘ืจื™ื ืขื ืกืจื˜ืŸ ื”ืขืจืžื•ื ื™ืช.
02:21
This is what's called a heat map --
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ื–ื•ื”ื™ ืžืคืช ื—ื•ื ืขื ืฆื‘ืขื™ื ืฉื•ื ื™ื,
02:23
and the different colors -- and along the side, on the right, are different genes.
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ื•ื‘ืฆื“ ื™ืžื™ืŸ ืžื•ืคื™ืขื” ืจืฉื™ืžืช ื’ื ื™ื.
02:26
And we found that over 500 genes were favorably changed --
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ื’ื™ืœื™ื ื• ืฉื™ื•ืชืจ ืž-500 ื’ื ื™ื ื”ืฉืชื ื• ืœื˜ื•ื‘ื”,
02:29
in effect, turning on the good genes, the disease-preventing genes,
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ื”ื’ื ื™ื ื”ื˜ื•ื‘ื™ื, ืžื•ื ืขื™ ื”ืžื—ืœื•ืช, ื”ื•ืคืขืœื•,
02:32
turning off the disease-promoting genes.
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ื•ื”ื’ื ื™ื ืžืขื•ื“ื“ื™ ื”ืžื—ืœื•ืช ื›ื•ื‘ื•.
02:36
And so these findings I think are really very powerful,
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ืžืžืฆืื™ื ืืœื” ื—ื–ืงื™ื ืžืื•ื“ ื•ื”ื ืžืขื ื™ืงื™ื
02:39
giving many people new hope and new choices.
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ืœืื ืฉื™ื ืจื‘ื™ื ืชืงื•ื•ื” ื—ื“ืฉื” ื•ืืคืฉืจื•ื™ื•ืช ื—ื“ืฉื•ืช.
02:41
And companies like Navigenics and DNA Direct and 23andMe,
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ื—ื‘ืจื•ืช ื›ืžื• "ื ืื‘ื™ื’ื ื™ืงืก", "ื“ื™ื™ืจืงื˜ ื“ื "ื" ื•ืขื•ื“
02:46
that are giving you your genetic profiles,
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ืฉืžืกืคืงื•ืช ืคืจื•ืคื™ืœื™ื ื’ื ื˜ื™ื™ื,
02:49
are giving some people a sense of, "Gosh, well, what can I do about it?"
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ื ื•ืชื ื•ืช ืœืื ืฉื™ื ืชื—ื•ืฉื” ืฉืœ "ืืœื•ื”ื™ื ืื“ื™ืจื™ื, ืžื” ืืคืฉืจ ืœืขืฉื•ืช?"
02:52
Well, our genes are not our fate, and if we make these changes --
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ื•ื‘ื›ืŸ, ื”ื’ื ื™ื ืฉืœื ื• ื”ื ืœื ื”ื’ื•ืจืœ ืฉืœื ื•,
02:55
they're a predisposition -- but if we make bigger changes
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ื”ื ื ื˜ื™ื” ืžื•ืงื“ืžืช.
02:57
than we might have made otherwise,
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ื•ืื ื ื‘ืฆืข ืฉื™ื ื•ื™ื™ื ื’ื“ื•ืœื™ื ื™ื•ืชืจ,
02:59
we can actually change how our genes are expressed.
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ื ื•ื›ืœ ืœืฉื ื•ืช ืืช ื”ื“ืจืš ื‘ื” ื™ืชื‘ื˜ืื• ื”ื’ื ื™ื ืฉืœื ื•.
ืชื•ื“ื”.
03:02
Thank you.
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03:03
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[ืžื—ื™ืื•ืช ื›ืคื™ื™ื]
ืขืœ ืืชืจ ื–ื”

ืืชืจ ื–ื” ื™ืฆื™ื’ ื‘ืคื ื™ื›ื ืกืจื˜ื•ื ื™ YouTube ื”ืžื•ืขื™ืœื™ื ืœืœื™ืžื•ื“ ืื ื’ืœื™ืช. ืชื•ื›ืœื• ืœืจืื•ืช ืฉื™ืขื•ืจื™ ืื ื’ืœื™ืช ื”ืžื•ืขื‘ืจื™ื ืขืœ ื™ื“ื™ ืžื•ืจื™ื ืžื”ืฉื•ืจื” ื”ืจืืฉื•ื ื” ืžืจื—ื‘ื™ ื”ืขื•ืœื. ืœื—ืฅ ืคืขืžื™ื™ื ืขืœ ื”ื›ืชื•ื‘ื™ื•ืช ื‘ืื ื’ืœื™ืช ื”ืžื•ืฆื’ื•ืช ื‘ื›ืœ ื“ืฃ ื•ื™ื“ืื• ื›ื“ื™ ืœื”ืคืขื™ืœ ืืช ื”ืกืจื˜ื•ืŸ ืžืฉื. ื”ื›ืชื•ื‘ื™ื•ืช ื’ื•ืœืœื•ืช ื‘ืกื ื›ืจื•ืŸ ืขื ื”ืคืขืœืช ื”ื•ื•ื™ื“ืื•. ืื ื™ืฉ ืœืš ื”ืขืจื•ืช ืื• ื‘ืงืฉื•ืช, ืื ื ืฆื•ืจ ืื™ืชื ื• ืงืฉืจ ื‘ืืžืฆืขื•ืช ื˜ื•ืคืก ื™ืฆื™ืจืช ืงืฉืจ ื–ื”.

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