Dr. Dean Ornish: Your genes are not your fate

Translator: Nafissa Yakubova Reviewer: Farrukh Yakubov

One way to change our genes is to make new ones,

Genlarimizni o'zgartirishning bir usuli yangi gen yaratish,

as Craig Venter has so elegantly shown.

buni Craig Venter yaxshilab ko'rsatdi.

Another is to change our lifestyles.

Boshqa usuli esa turmush tarzimizni o'zgartirish.

And what we're learning is how powerful and dynamic these changes can be,

Biz o'rganayotgan narsa bu o'zgarishlar qanchalik kuchga ega ekanligidir,

that you don't have to wait very long to see the benefits.

yani, foydali natijalarni ko'rish uchun siz uzoq kutib o'tirmaysiz.

When you eat healthier, manage stress, exercise and love more,

Qachonki sog'lom yesangiz, g'ayg'urish va stressni boshqara olsangiz, ko'proq sevsangiz

your brain actually gets more blood flow and more oxygen.

miyangiz chindan ham ko'proq kislorod va qon aylanishini yaxshilaydi.

But more than that, your brain gets measurably bigger.

Undan ham ko'proq, miyangiz o'lchami oshadi.

Things that were thought impossible just a few years ago

Bir necha yil avval mumkin emas deb o'ylagan narsalar

can actually be measured now.

endi hozir o'lchana oladi.

This was figured out by Robin Williams

Buni Robin Williams bilib bo'lgan edi

a few years before the rest of us.

bizdan burun bir necha yil avval.

Now, there's some things that you can do

Endi, siz qilsangiz bo'ladigan bir qator narsalar bor

to make your brain grow new brain cells.

yani miyangizni yangi hujayralar o'stirish uchun.

Some of my favorite things, like chocolate and tea, blueberries,

Men yaxshi ko'rgan narsalardan, masalan shokolod, choy, smorodina

alcohol in moderation, stress management

meyorida biroz alkogol, stress boshqarish

and cannabinoids found in marijuana.

va Marihuanada topilgan kanaboidlar.

I'm just the messenger.

Men shunchaki aytayapman .

(Laughter)

(Kulgi)

What were we just talking about?

Nima haqida gapirayotgan edik?

(Laughter)

(Kulgi)

And other things that can make it worse,

Ba'zi narsalar vaziyatni yomonlashtiradi

that can cause you to lose brain cells.

miya hujayralarini nobud qila oladi.

The usual suspects, like saturated fat and sugar,

Odatdagi ayblanuvchilar, to'yingan yog' va shakar,

nicotine, opiates, cocaine, too much alcohol and chronic stress.

nikotin, nasha, kokain,ortiqcha alkogol va uzoq muddatga cho'zilgan stress, og'ir ish.

Your skin gets more blood flow when you change your lifestyle,

Siz turmush tarszingizni o'zgartirganda, terisingizda yaxshi qon aylanadi,

so you age less quickly. Your skin doesn't wrinkle as much.

sekinroq qariysiz, teringizga unha ko'p ajin tushmaydi.

Your heart gets more blood flow.

Yuragingizda qon aylanish yaxshilanadi.

We've shown that you can actually reverse heart disease.

Biz yurak kasalliklarini orqaga qaytarish mumkinligi ko'rsata oldik.

That these clogged arteries that you see on the upper left,

Mana bu bekilib qolgan arteriyalarni ko'rayapsizmi chap yuqori qismda,

after only a year become measurably less clogged.

atigi bir yildan keyingina arteriya to'lib qolishi ancha kamaygan.

And the cardiac PET scan shown on the lower left,

Yurak PET skanirovaniya qilganda pastki chap qismda

the blue means no blood flow.

ko'k rang qon aylanmayapti degani.

A year later -- orange and white is maximum blood flow.

Bir yildan so'ng- to'q sarir va oq rangda eng katta maximum qon aylaniyishi.

We've shown you may be able to stop and reverse the progression

Biz sizga ko'rsatgandek, kasallikni to'xtatish va uni orqaga qaytarish mumkin,

of early prostate cancer and, by extension, breast cancer,

erta prostata raki, va ko'krak rakini orqaga qaytarish mumkin

simply by making these changes.

shunchaki shunday kichik bir o'zgartishlar kiritish bilan.

We've found that tumor growth in vitro was inhibited

Laboratoriyda o'smaning o'sishi 70% ga to'xtatilgan

70 percent in the group that made these changes,

qachonki biz bir guruhga o'zgartirish kiritganda

whereas only nine percent in the comparison group.

va o'zgartirihs kiritmaganda faqat 9% gina to'xtatilgan.

These differences were highly significant.

Bu farqlar juda katta ahamiyatga ega.

Even your sexual organs get more blood flow,

Hatto jinsiy organlarda ham yaxshi qon aylanadi.

so you increase sexual potency.

va jinsiy potentsial oshadi.

One of the most effective anti-smoking ads was done

chekishga qarshi qilingan reklamalarning eng foydalisi

by the Department of Health Services,

Sog'liqni saqlash xizmati tomonidan,

showing that nicotine, which constricts your arteries,

shuni ko'rsatadiki, nikotin arteriya qon tomirlarini toraytiradi

can cause a heart attack or a stroke,

va yurak huruji va insult keltirib chiqaradi,

but it also causes impotence.

lekin yana u jinsiy impotentsiyaga olib keladi.

Half of guys who smoke are impotent.

Chekuvchi erkaklarning yarimi nasl qoldirishga yaroqsiz, impotetentdir.

How sexy is that?

Qani aytingchi bu qanchalik et'tiborga loyiq?

Now we're also about to publish a study --

Endi biz ilmiy ishni nashr qilmoqchimiz-

the first study showing you can change gene expression in men with prostate cancer.

bu erkaklarda prostatta rakidagi genlarning aks ettishini o'zgartiirsh haqida.

This is what's called a heat map --

Bu issiq xarita deb nomlanadi

and the different colors -- and along the side, on the right, are different genes.

har hil ranglar , va har hil genlar o'ng tomonda.

And we found that over 500 genes were favorably changed --

Biz shuni topdikki 500 dna ortiq gen yaxhshi tomonga o'zgargan

in effect, turning on the good genes, the disease-preventing genes,

yani yaxhsi genlar ishga tushgan, yani kasallikning oldini oluvchi genlar

turning off the disease-promoting genes.

kasalik qo'zg'atuvchi genlarni "o'chirgan"

And so these findings I think are really very powerful,

Menimcha bu natijalar juda muhim

giving many people new hope and new choices.

va odamlarga yangi umid va tanlov beradi

And companies like Navigenics and DNA Direct and 23andMe,

Navigenix va DNA direct va 23andME kabi kompaniyalar

that are giving you your genetic profiles,

sizning genetic xaritalaringizni berayapti

are giving some people a sense of, "Gosh, well, what can I do about it?"

va ba'zi odamlar " bu bilan nima qilaman?" deb aytadi.

Well, our genes are not our fate, and if we make these changes --

Lekin, genlarimiz bizning taqdirimiz emas, agar biz o'zgarishlar kiritsak-

they're a predisposition -- but if we make bigger changes

katta o'zgarishlar kiritsak

than we might have made otherwise,

boshqa xato qilish o'rniga,

we can actually change how our genes are expressed.

biz chindan ham genlarimizning qanday ishlashini o'zgartira olamiz.

Thank you.

Rahmat.

(Applause)

(Qarsaklar)