Lee Cronin: Print your own medicine

Translator: Timothy Covell Reviewer: Morton Bast

Translator: Elona Eski Reviewer: Helena Bedalli

Organic chemists make molecules,

Kimistet organike krijojne molekula,

very complicated molecules,

molekuala shume te nderlikuara,

by chopping up a big molecule into small molecules

duke ndare nje molekule te madhe ne molekula te vogla

and reverse engineering.

dhe reverse engineering.

And as a chemist,

Si kimist,

one of the things I wanted to ask my research group a couple of years ago is,

nje nga pyetjet qe desha t`i beja grupit tim te kerkimit disa vite me pare eshte,

could we make a really cool universal chemistry set?

nese ishim ne gjendje te krijonim nje set kimik?

In essence, could we "app" chemistry?

Me pak fjale, nqse mund te krijonim nje 'app' per kimine?

Now what would this mean, and how would we do it?

Cdo me thene kjo, dhe si mund ta benim kete?

Well to start to do this,

Si fillim, per te bere kete

we took a 3D printer

ne morem nje printer 3D

and we started to print our beakers and our test tubes on one side

dhe filluam te printojme mjetet e laboratorit dhe provezat

and then print the molecule at the same time on the other side

dhe ne te njejten kohe, te printojme molekulen ne anen tjeter

and combine them together in what we call reactionware.

dhe t`i kombinonim bashke ne ate qe ne e quajtem reactionware.

And so by printing the vessel and doing the chemistry at the same time,

Keshtu qe duke printuar mjetet dhe bere kimi ne te njejten kohe

we may start to access this universal toolkit of chemistry.

ne mund te fillonim te kishim akses ne kete sistem universal per te bere kimi.

Now what could this mean?

Tani, cfare domethenie ka kjo?

Well if we can embed biological and chemical networks like a search engine,

Nqse ne mund te kombinonim rrjetet kimike dhe biologjike si nje motor kerkimi

so if you have a cell that's ill that you need to cure

keshtu qe nqse ti ke nje qelize qe do te sherosh

or bacteria that you want to kill,

ose nje bakterie qe do te vrasesh,

if you have this embedded in your device

nqse e ke kete brenda ne sistemin tend

at the same time, and you do the chemistry,

ne te njejten kohe, dhe ti ben veprime kimike,

you may be able to make drugs in a new way.

mund te jesh ne gjendje te prodhosh ilace ne nje menyre te re.

So how are we doing this in the lab?

Atehere si mund ta realizojme kete ne laborator?

Well it requires software, it requires hardware

Kjo kerkon software dhe hardware

and it requires chemical inks.

dhe kerkon bojera kimike.

And so the really cool bit is,

Keshtu, ajo qe eshte interesante

the idea is that we want to have a universal set of inks

eshte ideja qe ne duam te kemi nje set universal bojerash

that we put out with the printer,

qe vendosim ne printer

and you download the blueprint, the organic chemistry for that molecule

dhe ti downloadon modelin, formulen organike per ate molekule

and you make it in the device.

dhe e krijon ate ne sistem.

And so you can make your molecule in the printer using this software.

Keshtu qe ti mund te krijosh molekula ne nje printer duke perdorur kete program.

So what could this mean?

Cfare do te thote kjo?

Well, ultimately, it could mean that you could print your own medicine.

Perfundimisht, mund te themi qe ti mund te printosh ilacin tend.

And this is what we're doing in the lab at the moment.

dhe kjo eshte ajo qe po bejme ne laborator ne kete moment.

But to take baby steps to get there,

Por, duke bere hapa te vegjel te shkojme atje,

first of all we want to look at drug design and production,

si fillim ne duam te shikojme dizajnin e ilacit dhe prodhimin,

or drug discovery and manufacturing.

ose zbulimin e ilacit dhe menyren si ta krijosh.

Because if we can manufacture it after we've discovered it,

Sepse nqse mund ta krijojme pasi e kemi zbuluar,

we could deploy it anywhere.

mund ta ndertojme ate kudo.

You don't need to go to the chemist anymore.

Dhe njerezit nuk do te kene nevoje te shkojne me tek farmacisti.

We can print drugs at point of need.

Ne mund te printojme ilace sa here qe kemi nevoje.

We can download new diagnostics.

Ne mund te downloadojme diagnoza te reja.

Say a new super bug has emerged.

Psh nje parazit i ri ka shperthyer.

You put it in your search engine,

Ti e vendos ne motorrin e kerkimit,

and you create the drug to treat the threat.

dhe krijon ilacin per te trajtuar kete problem.

So this allows you on-the-fly molecular assembly.

Keshtu qe kjo te lejon asemblim te menjehershem te molekulave.

But perhaps for me the core bit going into the future

Por ndoshta per mua, copeza per te shkuar drejt se ardhmes

is this idea of taking your own stem cells,

eshte ideja qe te marresh qelizat e tua stem

with your genes and your environment,

me genet e tua dhe ambientin tend,

and you print your own personal medicine.

dhe te printosh ilacin tend personal.

And if that doesn't seem fanciful enough,

Dhe nqse kjo nuk te duket mjaft interesante,

where do you think we're going to go?

ku mendon se do te arrijme?

Well, you're going to have your own personal matter fabricator.

Ne kete rast, ti do te kesh fabrikuesin tend personal te materies.

Beam me up, Scotty.

Me drejto projektorin, Scotty.

(Applause)

(Duartrokitje)