Lee Cronin: Print your own medicine

88,003 views ・ 2013-02-07

TED


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00:00
Translator: Timothy Covell Reviewer: Morton Bast
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Prevoditelj: Senzos Osijek Recezent: Katarina Smetko
00:16
Organic chemists make molecules,
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Organski kemičari prave molekule,
00:18
very complicated molecules,
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vrlo komplicirane molekule,
00:20
by chopping up a big molecule into small molecules
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tako što cijepaju velike molekule u manje
00:24
and reverse engineering.
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i zatim primjenjuju obrnuti inženjering
00:25
And as a chemist,
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Kao kemičar,
00:27
one of the things I wanted to ask my research group a couple of years ago is,
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prije nekoliko sam godina htio pitati svoju istraživačku skupinu
00:30
could we make a really cool universal chemistry set?
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možemo li napraviti jedan cool univerzalni set za kemiju?
00:34
In essence, could we "app" chemistry?
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U biti, možemo li kemiju učiniti aplikacijom?
00:39
Now what would this mean, and how would we do it?
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Što bi to značilo i kako bismo to učinili?
00:42
Well to start to do this,
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Kako bismo započeli s time,
00:44
we took a 3D printer
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uzeli smo 3D pisač
00:46
and we started to print our beakers and our test tubes on one side
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i počeli ispisivati čaše i epruvete s jedne strane,
00:50
and then print the molecule at the same time on the other side
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a molekule istovremeno s druge strane.
00:54
and combine them together in what we call reactionware.
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Kombinirali smo ih kako bismo dobili tzv. "reactionware."
00:58
And so by printing the vessel and doing the chemistry at the same time,
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Ispisivanje posude i istovremeno obavljanje kemijskih radnji
01:02
we may start to access this universal toolkit of chemistry.
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moglo bi biti prvi korak prema tom univerzalnom setu za kemiju.
01:07
Now what could this mean?
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Što bi to moglo značiti?
01:09
Well if we can embed biological and chemical networks like a search engine,
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Kad bismo mogli ugraditi biološke i kemijske mreže poput pretraživača,
01:14
so if you have a cell that's ill that you need to cure
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tako da, ako imate stanicu koja je bolesna i koju trebate liječiti,
01:17
or bacteria that you want to kill,
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ili imate bakteriju koju želite ubiti,
01:19
if you have this embedded in your device
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ako to imate ugrađeno u svoj uređaj u isto vrijeme,
01:21
at the same time, and you do the chemistry,
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i obavite kemijske radnje,
01:24
you may be able to make drugs in a new way.
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mogli biste izraditi lijekove na nov način.
01:27
So how are we doing this in the lab?
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Kako mi to činimo u laboratoriju?
01:30
Well it requires software, it requires hardware
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Za to je potreban softver, kao i hardver.
01:33
and it requires chemical inks.
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Potrebne su i kemijske tinte.
01:35
And so the really cool bit is,
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A najzanimljivija je ideja
01:37
the idea is that we want to have a universal set of inks
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da želimo imati univerzalan set tinta
01:40
that we put out with the printer,
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koje ćemo dati s pisačem,
01:42
and you download the blueprint, the organic chemistry for that molecule
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vi učitate nacrt, organsku kemiju za tu molekulu
01:46
and you make it in the device.
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i napravite je u uređaju.
01:49
And so you can make your molecule in the printer using this software.
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Tako možete svoju molekulu možete načiniti u pisaču, koristeći ovaj softver.
01:55
So what could this mean?
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Što bi to moglo značiti?
01:57
Well, ultimately, it could mean that you could print your own medicine.
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U konačnici, moglo bi značiti da biste mogli ispisivati sami svoje lijekove.
02:02
And this is what we're doing in the lab at the moment.
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To upravo činimo u laboratoriju.
02:04
But to take baby steps to get there,
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Ali kako bismo činili male korake prema tome cilju,
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first of all we want to look at drug design and production,
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prvo želimo vidjeti oblikovanje i proizvodnju lijeka,
02:09
or drug discovery and manufacturing.
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ili otkrivanje i izradu.
02:11
Because if we can manufacture it after we've discovered it,
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Ako ih možemo proizvesti nakon što smo ih otkrili,
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we could deploy it anywhere.
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možemo ih poslati bilo kamo.
02:16
You don't need to go to the chemist anymore.
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Ne morate više ići u ljekarnu.
02:18
We can print drugs at point of need.
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Možemo ispisivati lijekove prema potrebi.
02:21
We can download new diagnostics.
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Možemo učitavati nove dijagnostike.
02:24
Say a new super bug has emerged.
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Recimo da se pojavi nov uzročnik bolesti.
02:26
You put it in your search engine,
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Stavite ga u svoj pretraživač
02:27
and you create the drug to treat the threat.
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i napravite lijek koji će riješiti taj problem.
02:30
So this allows you on-the-fly molecular assembly.
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To vam omogućava trenutno sastavljanje molekula.
02:34
But perhaps for me the core bit going into the future
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Ali za mene je bit koju ćemo razraditi u budućnosti
02:37
is this idea of taking your own stem cells,
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ideja uzimanja vlastitih matičnih stanica,
02:40
with your genes and your environment,
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s vlastitim genima i okolinom,
02:42
and you print your own personal medicine.
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i ispisivanje vlastitih personaliziranih lijekova.
02:46
And if that doesn't seem fanciful enough,
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Ako se to ne čini dovoljno nestvarno,
02:48
where do you think we're going to go?
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što mislite, što ćemo sljedeće učiniti?
02:50
Well, you're going to have your own personal matter fabricator.
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Imat ćemo svoj osobni proizvođač tvari.
02:54
Beam me up, Scotty.
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Teleportiraj me, Scotty.
02:56
(Applause)
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(Pljesak)
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