Lee Cronin: Print your own medicine

88,003 views ・ 2013-02-07

TED


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Translator: Timothy Covell Reviewer: Morton Bast
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Organic chemists make molecules,
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very complicated molecules,
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by chopping up a big molecule into small molecules
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and reverse engineering.
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And as a chemist,
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one of the things I wanted to ask my research group a couple of years ago is,
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could we make a really cool universal chemistry set?
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In essence, could we "app" chemistry?
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Now what would this mean, and how would we do it?
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Well to start to do this,
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we took a 3D printer
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and we started to print our beakers and our test tubes on one side
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and then print the molecule at the same time on the other side
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and combine them together in what we call reactionware.
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And so by printing the vessel and doing the chemistry at the same time,
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we may start to access this universal toolkit of chemistry.
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Now what could this mean?
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Well if we can embed biological and chemical networks like a search engine,
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so if you have a cell that's ill that you need to cure
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or bacteria that you want to kill,
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if you have this embedded in your device
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at the same time, and you do the chemistry,
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you may be able to make drugs in a new way.
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So how are we doing this in the lab?
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Well it requires software, it requires hardware
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and it requires chemical inks.
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And so the really cool bit is,
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the idea is that we want to have a universal set of inks
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that we put out with the printer,
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and you download the blueprint, the organic chemistry for that molecule
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and you make it in the device.
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And so you can make your molecule in the printer using this software.
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So what could this mean?
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Well, ultimately, it could mean that you could print your own medicine.
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And this is what we're doing in the lab at the moment.
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But to take baby steps to get there,
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first of all we want to look at drug design and production,
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or drug discovery and manufacturing.
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Because if we can manufacture it after we've discovered it,
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we could deploy it anywhere.
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You don't need to go to the chemist anymore.
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We can print drugs at point of need.
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We can download new diagnostics.
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Say a new super bug has emerged.
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You put it in your search engine,
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and you create the drug to treat the threat.
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So this allows you on-the-fly molecular assembly.
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But perhaps for me the core bit going into the future
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is this idea of taking your own stem cells,
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with your genes and your environment,
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and you print your own personal medicine.
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And if that doesn't seem fanciful enough,
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where do you think we're going to go?
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Well, you're going to have your own personal matter fabricator.
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Beam me up, Scotty.
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(Applause)
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