Lee Cronin: Print your own medicine

88,565 views ・ 2013-02-07

TED


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00:00
Translator: Timothy Covell Reviewer: Morton Bast
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Translator: Nika Kotnik Reviewer: Matej Divjak
00:16
Organic chemists make molecules,
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Kemiki organske kemije izdelujejo molekule,
00:18
very complicated molecules,
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zelo zapletene molekule,
00:20
by chopping up a big molecule into small molecules
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tako, da razkosajo veliko molekulo v majhne molekule
00:24
and reverse engineering.
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in obratno.
00:25
And as a chemist,
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In kot kemik,
je bila ena od stvari, ki sem jih hotel vprašati svojo raziskovalno ekipo nekaj let nazaj,
00:27
one of the things I wanted to ask my research group a couple of years ago is,
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00:30
could we make a really cool universal chemistry set?
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ali bi lahko naredili res kul univerzalen set za kemijo?
00:34
In essence, could we "app" chemistry?
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V bistvu, bi lahko naredili aplikacijo za kemijo?
00:39
Now what would this mean, and how would we do it?
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Kaj bi to pomenilo in kako bi to naredili?
00:42
Well to start to do this,
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No, da bi začeli s tem,
00:44
we took a 3D printer
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smo vzeli 3D tiskalnik
00:46
and we started to print our beakers and our test tubes on one side
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in začeli smo si tiskati čaše in epruvete na eni strani
00:50
and then print the molecule at the same time on the other side
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in potem hkrati tiskati molekule na drugi strani
00:54
and combine them together in what we call reactionware.
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in jih združili s procesom imenovanim "reactionware".
00:58
And so by printing the vessel and doing the chemistry at the same time,
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In tako bi s tiskanjem posod in kemije hkrati
01:02
we may start to access this universal toolkit of chemistry.
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morda lahko začeli z doseganjem tega univerzalnega seta za kemijo.
01:07
Now what could this mean?
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In kaj bi to pomenilo?
01:09
Well if we can embed biological and chemical networks like a search engine,
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No, če lahko vgradimo biološka in kemična omrežja kot iskalnik,
01:14
so if you have a cell that's ill that you need to cure
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tako, da če imate celico, ki je bolna in jo morate pozdraviti,
01:17
or bacteria that you want to kill,
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ali bakterijo, ki jo hočete ubiti,
01:19
if you have this embedded in your device
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če imate to obenem vgrajeno v svojo napravo
01:21
at the same time, and you do the chemistry,
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in sprožite kemični proces,
01:24
you may be able to make drugs in a new way.
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boste morda lahko izdelovali zdravila na nov način.
01:27
So how are we doing this in the lab?
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Kako torej to počnemo v laboratoriju?
01:30
Well it requires software, it requires hardware
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Potrebna je programska oprema, potrebna je strojna oprema
01:33
and it requires chemical inks.
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in potrebna so kemična črnila.
01:35
And so the really cool bit is,
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In zares kul del je
01:37
the idea is that we want to have a universal set of inks
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ideja, da hočemo imeti univerzalni set črnil,
01:40
that we put out with the printer,
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ki jih prodamo skupaj s tiskalnikom
01:42
and you download the blueprint, the organic chemistry for that molecule
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in vi si prenesete načrt, organsko kemijo za to molekulo
01:46
and you make it in the device.
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in jo naredite v napravi.
01:49
And so you can make your molecule in the printer using this software.
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In tako lahko naredite svojo molekulo v tiskalniku z uporabo te programske opreme.
01:55
So what could this mean?
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Kaj bi to lahko pomenilo?
01:57
Well, ultimately, it could mean that you could print your own medicine.
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No, navsezadnje bi lahko pomenilo, da bi si natisnili svoje zdravilo.
02:02
And this is what we're doing in the lab at the moment.
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In to trenutno počnemo v laboratoriju.
02:04
But to take baby steps to get there,
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Ampak, da bi do tega prišli z majhnimi koraki,
02:06
first of all we want to look at drug design and production,
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moramo najprej pogledati oblikovanje in izdelavo zdravil,
02:09
or drug discovery and manufacturing.
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ali pa odkrivanje zdravil in proizvodnjo.
02:11
Because if we can manufacture it after we've discovered it,
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Ker, če jo lahko proizvedemo, potem ko smo jo odkrili,
02:14
we could deploy it anywhere.
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bi jo lahko namestili kamorkoli.
02:16
You don't need to go to the chemist anymore.
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Ni nam treba več k farmacevtu.
02:18
We can print drugs at point of need.
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Lahko natisnemo zdravila, ko jih potrebujemo.
02:21
We can download new diagnostics.
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Lahko naložimo nove diagnostične metode.
02:24
Say a new super bug has emerged.
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Recimo, da se pojavi nova superbakterija.
02:26
You put it in your search engine,
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Daš jo v svoj iskalnik
02:27
and you create the drug to treat the threat.
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in ustvariš zdravilo za zdravljenje te grožnje.
02:30
So this allows you on-the-fly molecular assembly.
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Tako ti to dovoljuje sprotno sestavljanje molekul.
02:34
But perhaps for me the core bit going into the future
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Ampak mogoče je zame glavni del za prihodnost
02:37
is this idea of taking your own stem cells,
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ta ideja, da bi vzeli svoje izvorne celice
02:40
with your genes and your environment,
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z vašimi geni in vašim okoljem
02:42
and you print your own personal medicine.
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in si natisnili svoje lastno zdravilo.
02:46
And if that doesn't seem fanciful enough,
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in če se vam to ne zdi dovolj domišljeno,
02:48
where do you think we're going to go?
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kam mislite, da bomo šli?
02:50
Well, you're going to have your own personal matter fabricator.
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No, imeli boste svoj lastni izdelovalec žive snovi.
02:54
Beam me up, Scotty.
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Prežarči me, Scotty.
02:56
(Applause)
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(Aplavz)
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