Peter Attia: What if we're wrong about diabetes?

2,677,011 views ・ 2013-06-25

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00:00
Translator: Joseph Geni Reviewer: Morton Bast
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Translator: Alicia Ferreiro Reviewer: Serv. de Norm. Lingüística U. de Santiago de Compostela
00:12
I'll never forget that day
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Nunca esquecerei ese día.
00:13
back in the spring of 2006.
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Era a primavera de 2006.
00:17
I was a surgical resident
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Eu era residente de cirurxía
00:19
at The Johns Hopkins Hospital,
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no Hospital Johns Hopkins,
00:21
taking emergency call.
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atendendo chamadas de urxencias.
00:23
I got paged by the E.R. around 2 in the morning
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Chamáronme para unha urxencia ás 2 da mañá:
00:26
to come and see a woman with a diabetic ulcer
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unha muller cunha úlcera diabética no pé.
00:28
on her foot.
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00:30
I can still remember sort of that smell of rotting flesh
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Aínda lembro aquela especie de cheiro a carne podre
00:34
as I pulled the curtain back to see her.
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mentres apartaba a cortina para vela.
00:38
And everybody there agreed this woman was very sick
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Todos coincidiamos en que estaba moi enferma
00:40
and she needed to be in the hospital.
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e tiña que estar ingresada
00:41
That wasn't being asked.
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Nin se formulaba a pregunta.
00:43
The question that was being asked of me was a different one,
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O que me estaban a preguntar era outra cousa:
00:45
which was, did she also need an amputation?
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tamén precisa dunha amputación?
00:49
Now, looking back on that night,
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Agora, mirando cara atrás, aquela noite,
00:52
I'd love so desperately to believe that I treated that woman
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gustaríame tanto crer que aquela noite
00:57
on that night with the same empathy and compassion
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a tratei coa mesma empatía e compaixón
01:00
I'd shown the 27-year-old newlywed
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que mostrara cunha acabada de casar de 27 anos
01:04
who came to the E.R. three nights earlier
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que chegara 3 noites antes
01:06
with lower back pain
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con dor lumbar,
01:08
that turned out to be advanced pancreatic cancer.
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que resultou ser cancro de páncreas avanzado.
01:12
In her case, I knew there was nothing I could do
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Sabía que non había nada que eu puidese facer
01:14
that was actually going to save her life.
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que de verdade lle salvase a vida.
01:16
The cancer was too advanced.
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O cancro estaba moi avanzado.
01:18
But I was committed to making sure that
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Pero empeñeime en garantir
01:21
I could do anything possible to make her stay
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que faría todo o posible para facer a súa estancia máis cómoda.
01:23
more comfortable. I brought her a warm blanket
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Tróuxenlle un cobertor
01:26
and a cup of a coffee.
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e unha cunca de café.
01:28
I brought some for her parents.
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Tamén para os seus pais.
01:31
But more importantly, see, I passed no judgment on her,
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Pero sobre todo non a xulguei,
01:34
because obviously she had done nothing
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xa que, obviamente, ela non fixera nada
01:36
to bring this on herself.
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para provocar a súa situación.
01:38
So why was it that, just a few nights later,
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Entón, por qué só un par de noites máis tarde,
01:41
as I stood in that same E.R. and determined
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cando, na mesma sala de urxencias,
01:44
that my diabetic patient did indeed need an amputation,
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determinei que a miña paciente diabética si precisaba unha amputación,
01:47
why did I hold her in such bitter contempt?
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por que sentín ese desprezo amargo?
01:51
You see, unlike the woman the night before,
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Pois porque, ao contrario da muller da noite anterior,
01:54
this woman had type 2 diabetes.
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esta muller tiña diabetes tipo 2.
01:56
She was fat.
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Estaba gorda.
01:58
And we all know that's from eating too much
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E todos sabemos que iso é de comer de máis
01:59
and not exercising enough, right?
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e non facer exercicio abondo, non si?
02:02
I mean, how hard can it be?
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Quero dicir, é tan difícil?
02:04
As I looked down at her in the bed, I thought to myself,
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Mentres a vía na cama, pensaba:
02:07
if you just tried caring even a little bit,
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se simplemente intentaras coidarte un pouco
02:10
you wouldn't be in this situation at this moment
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non estarías nesta situación agora,
02:13
with some doctor you've never met
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cun médico ao que nunca viras
02:14
about to amputate your foot.
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a punto de amputarche un pé.
02:18
Why did I feel justified in judging her?
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Por que me sentín con dereito a xulgala?
02:22
I'd like to say I don't know.
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Gustaríame dicir que non o sei.
02:25
But I actually do.
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Pero en realidade si que o sei.
02:27
You see, in the hubris of my youth,
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Co arrogancia da xuventude,
02:29
I thought I had her all figured out.
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pensei que o entendía.
02:32
She ate too much. She got unlucky.
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Comeu de máis. Tivo mala sorte.
02:34
She got diabetes. Case closed.
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Ten diabetes. Caso pechado.
02:37
Ironically, at that time in my life,
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Ironicamente, naquela época na miña vida,
02:39
I was also doing cancer research,
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tamén facía investigación sobre o cancro,
02:41
immune-based therapies for melanoma, to be specific,
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en concreto, terapia inmunolóxica para o melanoma,
02:43
and in that world I was actually taught to question everything,
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e nese mundo que me ensinou a cuestionar todo,
02:47
to challenge all assumptions
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a desafiar as presuncións
02:49
and hold them to the highest possible scientific standards.
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e levalas aos máis altos estándares científicos posibles.
02:53
Yet when it came to a disease like diabetes
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Con todo, cunha enfermidade como a diabetes
02:57
that kills Americans eight times more frequently than melanoma,
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que mata oito veces máis estadounidenses que o melanoma,
03:00
I never once questioned the conventional wisdom.
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nin unha vez cuestionei a sabedoría convencional.
03:04
I actually just assumed the pathologic sequence of events
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Asumín a secuencia patolóxica dos feitos
03:07
was settled science.
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como probada.
03:09
Three years later, I found out how wrong I was.
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Tres anos máis tarde, descubrín o equivocado que estaba.
03:13
But this time, I was the patient.
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Esta vez, o paciente era eu.
03:15
Despite exercising three or four hours every single day,
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A pesar de facer exercicio tres ou catro horas todos os días,
03:19
and following the food pyramid to the letter,
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de seguir a pirámide alimentaria ao pé da letra,
03:22
I'd gained a lot of weight and developed something
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gañei moito peso e desenvolvín algo chamado
03:24
called metabolic syndrome.
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síndrome metabólica.
03:26
Some of you may have heard of this.
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Algúns escoitarían falar dela.
03:28
I had become insulin-resistant.
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Fixérame resistente á insulina.
03:31
You can think of insulin as this master hormone
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Poden pensar na insulina como a hormona mestra
03:34
that controls what our body does with the foods we eat,
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que controla o que fai o noso corpo cos alimentos que comemos,
03:38
whether we burn it or store it.
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queimalos ou almacenalos.
03:40
This is called fuel partitioning in the lingo.
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Separación do combustible no argot.
03:43
Now failure to produce enough insulin is incompatible with life.
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Non producir insulina suficiente
é incompatible coa vida.
03:46
And insulin resistance, as its name suggests,
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E a resistencia á insulina, como o propio nome indica,
03:49
is when your cells get increasingly resistant
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é cando as células opoñen cada vez máis resistencia
03:51
to the effect of insulin trying to do its job.
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ao efecto da insulina tentando facer o seu traballo.
03:55
Once you're insulin-resistant,
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Cando un é resistente á insulina,
03:57
you're on your way to getting diabetes,
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está no camiño a padecer diabetes,
03:58
which is what happens when your pancreas
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que é o que pasa cando o páncreas
04:00
can't keep up with the resistance and make enough insulin.
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non pode superar a resistencia e producir insulina suficiente.
04:04
Now your blood sugar levels start to rise,
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Os niveis de azucre no sangue comezan a subir,
04:06
and an entire cascade of pathologic events
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e iniciase unha auténtica fervenza de eventos patolóxicos,
04:09
sort of spirals out of control that can lead to heart disease,
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unha espiral fóra de control, que pode levar a enfermidades cardíacas,
04:13
cancer, even Alzheimer's disease,
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cancro, mesmo alzheimer,
04:16
and amputations, just like that woman a few years earlier.
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e amputacións, como aquela muller uns anos antes.
04:21
With that scare, I got busy changing my diet radically,
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Con este susto, púxenme a cambiar a miña dieta radicalmente,
04:24
adding and subtracting things most of you would find
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poñendo e quitando cousas que a maioría
04:26
almost assuredly shocking.
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seguramente atoparían chocantes.
04:29
I did this and lost 40 pounds, weirdly while exercising less.
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Fíxeno e perdín 18 quilos, sorprendentemente facendo menos exercicio.
04:33
I, as you can see, I guess I'm not overweight anymore.
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Como se pode ver, creo que xa non teño sobrepeso
04:36
More importantly, I don't have insulin resistance.
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E sobre todo, tampouco resistencia á insulina.
04:39
But most important, I was left
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Pero, o máis importante,
04:41
with these three burning questions that wouldn't go away:
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quedei con estas tres cuestións candentes que non marchaban:
04:44
How did this happen to me if I was supposedly
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Como me pasou isto se, en teoría,
04:47
doing everything right?
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estaba facendo o correcto?
04:50
If the conventional wisdom about nutrition had failed me,
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A sabedoría convencional sobre nutrición fallárame.
04:53
was it possible it was failing someone else?
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Estaríalle fallando a alguén máis?
04:56
And underlying these questions,
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E, baixo estas preguntas,
04:58
I became almost maniacally obsessed
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obsesioneime dun xeito case maníaco
05:02
in trying to understand the real relationship
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con tentar entender a relación real
05:04
between obesity and insulin resistance.
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entre obesidade e resistencia á insulina.
05:08
Now, most researchers believe obesity
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A maioría dos investigadores consideran que a obesidade
05:11
is the cause of insulin resistance.
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é a causa da resistencia á insulina.
05:14
Logically, then, if you want to treat insulin resistance,
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Por lóxica, se se quere tratar a resistencia á insulina,
05:16
you get people to lose weight, right?
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faise que a xente perda peso, non?
05:18
You treat the obesity.
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Trátase a obesidade.
05:21
But what if we have it backwards?
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Pero, e se imos ó revés?
05:24
What if obesity isn't the cause of insulin resistance at all?
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E se a obesidade non é para nada a causa da resistencia á insulina?
05:27
In fact, what if it's a symptom of a much deeper problem,
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E se, de feito, é un síntoma dun problema moito máis profundo,
05:31
the tip of a proverbial iceberg?
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a punta dun iceberg proverbial?
05:34
I know it sounds crazy because we're obviously in the midst
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Sei que parece unha tolería, porque estamos, obviamente,
05:36
of an obesity epidemic, but hear me out.
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no medio dunha epidemia de obesidade. Pero, escoiten.
05:40
What if obesity is a coping mechanism
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E se a obesidade é un mecanismo para afrontar un problema
05:43
for a far more sinister problem going on
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moito máis sinistro baixo todo isto?
05:46
underneath the cell?
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05:48
I'm not suggesting that obesity is benign,
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Non digo que a obesidade sexa benigna,
05:50
but what I am suggesting is it may be the lesser
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o que digo é que pode ser o menor
05:53
of two metabolic evils.
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de dous males metabólicos.
05:55
You can think of insulin resistance as the reduced capacity
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Poden ver a resistencia á insulina como a capacidade reducida
05:58
of our cells to partition fuel,
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das nosas células para repartir o combustible,
06:00
as I alluded to a moment ago,
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como dixen hai pouco,
06:03
taking those calories that we take in
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tomar esas calorías que inxerimos
06:04
and burning some appropriately and storing some appropriately.
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queimar algunhas e almacenar outras adecuadamente.
06:08
When we become insulin-resistant,
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Cando nos facemos resistentes á insulina,
06:10
the homeostasis in that balance deviates from this state.
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a homeostase deste equilibrio desvíase deste estado.
06:13
So now, when insulin says to a cell,
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Así, cando a insulina lle di a unha célula:
06:15
I want you to burn more energy
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Quero que queimes máis enerxía
06:17
than the cell considers safe, the cell, in effect, says,
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do que a célula considera seguro, a célula di:
06:20
"No thanks, I'd actually rather store this energy."
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"Non, grazas, prefiro almacenar esa enerxía."
06:24
And because fat cells are actually missing most of
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E como as células de graxa carecen da maioría
06:26
the complex cellular machinery found in other cells,
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da complexa maquinaria atopada noutras células,
06:29
it's probably the safest place to store it.
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seguramente sexan o lugar máis seguro para almacenala.
06:31
So for many of us, about 75 million Americans,
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Así, para moitos de nós, uns 75 millóns de estadounidenses,
06:36
the appropriate response to insulin resistance
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a resposta adecuada á resistencia á insulina
06:40
may actually be to store it as fat, not the reverse,
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pode ser almacenalo como graxa, e non ó contrario,
06:45
getting insulin resistance in response to getting fat.
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desenvolver resistencia á insulina como resultado de engordar.
06:50
This is a really subtle distinction,
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É unha diferenza moi sutil,
06:52
but the implication could be profound.
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pero as implicacións poden ser profundas.
06:56
Consider the following analogy:
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Consideren a seguinte analoxía:
06:58
Think of the bruise you get on your shin
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Pensen nunha mazadura que se produce nunha canela,
07:01
when you inadvertently bang your leg into the coffee table.
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cando sen darse conta baten coa mesa do café,
07:05
Sure, the bruise hurts like hell, and you almost certainly
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Por suposto, a lesión doe moitísimo, e seguramente
07:08
don't like the discolored look, but we all know
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non lle guste a aparencia descolorida, pero todos sabemos
07:11
the bruise per Se is not the problem.
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que a lesión en si non é o problema.
07:14
In fact, it's the opposite. It's a healthy response to the trauma,
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En realidade, é o contrario. É unha resposta saudable ao trauma,
07:18
all of those immune cells rushing to the site of the injury
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todas as células inmunitarias correndo ó lugar da lesión
07:21
to salvage cellular debris and prevent the spread
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para salvar os restos celulares e evitar a propagación
07:24
of infection to elsewhere in the body.
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da infección a outras partes do corpo.
07:26
Now, imagine we thought bruises were the problem,
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Agora imaxinen que pensásemos que as mazaduras eran o problema,
07:30
and we evolved a giant medical establishment
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e desenvolvésemos un sistema médico xigante,
07:33
and a culture around treating bruises:
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e unha cultura arredor do tratamento das mazaduras:
07:36
masking creams, painkillers, you name it,
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cremas de enmascaramento, analxésicos, de todo,
07:39
all the while ignoring the fact that people
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en todo momento ignorando o feito de que a xente
07:42
are still banging their shins into coffee tables.
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segue a bater coas canelas nas mesas do café.
07:45
How much better would we be if we treated the cause --
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Canto mellor sería se tratásemos a causa,
07:48
telling people to pay attention
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--avisando á xente de que teña conta
07:50
when they walk through the living room --
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cando ande pola sala de estar--
07:52
rather than the effect?
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en vez do efecto?
07:55
Getting the cause and the effect right
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Interpretar a causa e o efecto correctamente
07:57
makes all the difference in the world.
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marca a diferenza por completo.
07:59
Getting it wrong, and the pharmaceutical industry
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Se o interpretamos incorrectamente, a industria farmacéutica
08:02
can still do very well for its shareholders
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aínda o estaría a facer moi ben para os seus accionistas
08:05
but nothing improves for the people with bruised shins.
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pero nada mellora para as persoas con pernas moradas.
08:09
Cause and effect.
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Causa e efecto.
08:12
So what I'm suggesting is
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O que eu suxiro é que,
08:14
maybe we have the cause and effect wrong
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se cadra entendemos mal a relación causa-efecto
08:16
on obesity and insulin resistance.
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entre a obesidade e a resistencia á insulina.
08:19
Maybe we should be asking ourselves,
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Se cadra deberámonos preguntar,
08:21
is it possible that insulin resistance causes weight gain
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é posible que a resistencia á insulina cause o aumento de peso
08:25
and the diseases associated with obesity,
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e as enfermidades asociadas coa obesidade,
08:27
at least in most people?
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polo menos na maioría das persoas?
08:28
What if being obese is just a metabolic response
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E se ser obeso é só unha resposta metabólica
08:31
to something much more threatening,
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a algo moito máis ameazante,
08:34
an underlying epidemic,
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unha epidemia subxacente,
08:36
the one we ought to be worried about?
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que é polo que deberiamos estar preocupados?
08:38
Let's look at some suggestive facts.
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Vexamos uns feitos rechamantes.
08:40
We know that 30 million obese Americans
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Sabemos que 30 millóns de estadounidenses obesos
08:42
in the United States don't have insulin resistance.
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non teñen a resistencia á insulina.
08:45
And by the way, they don't appear to be at any
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E, a propósito, non parecen ter
08:47
greater risk of disease than lean people.
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maior risco de enfermidade que as persoas delgadas.
08:50
Conversely, we know that six million lean people
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Por outra banda, sabemos que seis millóns de persoas fracas
08:53
in the United States are insulin-resistant,
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nos Estados Unidos son insulinorresistentes,
08:57
and by the way, they appear to be at even greater risk
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e, por certo, parecen presentar un risco aínda maior de padecer
09:00
for those metabolic diseases I mentioned a moment ago
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estas enfermidades metabólicas que mencionaba
09:02
than their obese counterparts.
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que os seus homólogos obesos.
09:04
Now I don't know why, but it might be because,
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Non sei o porqué, pero podería ser porque
09:06
in their case, their cells haven't actually figured out
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neste caso, as células non descubriron
09:09
the right thing to do with that excess energy.
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o correcto que facer co exceso de enerxía.
09:12
So if you can be obese and not have insulin resistance,
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Entón, pódese ser obeso e non ter resistencia á insulina,
09:15
and you can be lean and have it,
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e pódese estar delgada e tela.
09:17
this suggests that obesity may just be a proxy
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Isto suxire que a obesidade pode ser só un representante
09:21
for what's going on.
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do que está sucedendo.
09:24
So what if we're fighting the wrong war,
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E se estamos loitando a guerra equivocada,
09:27
fighting obesity rather than insulin resistance?
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a loita contra a obesidade, no canto da resistencia á insulina?
09:31
Even worse, what if blaming the obese
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Peor aínda, e se culpar ós obesos
09:34
means we're blaming the victims?
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significa que estamos culpando ás vítimas?
09:37
What if some of our fundamental ideas about obesity
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E se algunha das nosas ideas fundamentais sobre a obesidade están mal?
09:40
are just wrong?
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09:42
Personally, I can't afford the luxury of arrogance anymore,
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Persoalmente, xa non me permito o luxo da arrogancia
09:46
let alone the luxury of certainty.
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e moito menos o luxo da certeza.
09:49
I have my own ideas about what could be at the heart of this,
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Teño as miñas propias ideas sobre isto,
09:52
but I'm wide open to others.
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pero estou aberto a outras.
09:54
Now, my hypothesis, because everybody always asks me,
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A miña hipótese, porque todo o mundo ma pregunta é:
09:56
is this.
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09:58
If you ask yourself, what's a cell trying to protect itself from
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Se te preguntas, de que se intenta protexer unha célula
10:01
when it becomes insulin resistant,
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cando se fai resistente á insulina?
10:03
the answer probably isn't too much food.
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a resposta probablemente non sexa: demasiada comida.
10:06
It's more likely too much glucose: blood sugar.
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Probablemente é a glicosa: azucre no sangue.
10:09
Now, we know that refined grains and starches
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Agora sabemos que os grans refinados e o amidón
10:11
elevate your blood sugar in the short run,
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elevan o azucre no sangue a curto prazo.
10:14
and there's even reason to believe that sugar
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Hai incluso razóns para crer que o azucre
10:15
may lead to insulin resistance directly.
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poida levar á resistencia á insulina directamente.
10:18
So if you put these physiological processes to work,
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Se poñemos eses procesos fisiolóxicos a traballar,
10:22
I'd hypothesize that it might be our increased intake
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a miña hipótese é que é posible que o aumento na inxesta
10:26
of refined grains, sugars and starches that's driving
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de grans refinados, azucres e amidón nos estea levando
10:29
this epidemic of obesity and diabetes,
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á epidemia de obesidade e diabetes,
10:33
but through insulin resistance,
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pero a través da resistencia á insulina,
10:35
you see, and not necessarily through just overeating and under-exercising.
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e non necesariamente por exceso de comida
e falta de exercicio.
10:39
When I lost my 40 pounds a few years ago,
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Cando eu perdín os 18 quilos,
10:42
I did it simply by restricting those things,
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fíxeno eliminando estas cousas,
10:44
which admittedly suggests I have a bias
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polo que admito que teño unha inclinación
10:48
based on my personal experience.
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baseada na miña experiencia persoal.
10:50
But that doesn't mean my bias is wrong,
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Pero iso non significa que o meu prexuízo sexa malo,
10:53
and most important, all of this can be tested scientifically.
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e o máis importante, todo isto pode ser probado cientificamente.
10:57
But step one is accepting the possibility
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O primeiro paso é aceptar a posibilidade
11:00
that our current beliefs about obesity,
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de que as nosas ideas actuais sobre obesidade,
11:02
diabetes and insulin resistance could be wrong
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a diabetes e a resistencia á insulina poidan ser incorrectas
11:05
and therefore must be tested.
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e, polo tanto, deben ser comprobadas.
11:08
I'm betting my career on this.
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Aposto a miña carreira nisto.
11:10
Today, I devote all of my time to working on this problem,
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Hoxe, dedico todo o meu tempo a traballar neste problema,
11:15
and I'll go wherever the science takes me.
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e eu vou cara a onde a ciencia me leva.
11:18
I've decided that what I can't and won't do anymore
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Decidín que o que nin podo nin vou facer máis
11:21
is pretend I have the answers when I don't.
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é finxir que teño as respostas cando non as teño.
11:24
I've been humbled enough by all I don't know.
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Xa me humillei o suficiente con todo o que non sei.
11:28
For the past year, I've been fortunate enough
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No último ano, tiven a sorte
11:31
to work on this problem with the most amazing team
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de traballar neste problema co equipo máis incrible
11:34
of diabetes and obesity researchers in the country,
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de investigadores en diabetes e obesidade de todo o país,
11:37
and the best part is,
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e o mellor é que,
11:39
just like Abraham Lincoln surrounded himself with a team of rivals,
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tal como Abraham Lincoln se rodeara de rivais
11:43
we've done the same thing.
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fixemos o mesmo.
11:44
We've recruited a team of scientific rivals,
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Xuntamos un equipo de científicos rivais
11:47
the best and brightest who all have different hypotheses
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o mellor e máis brillante entre os que teñen distintas hipóteses
11:51
for what's at the heart of this epidemic.
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sobre o centro desta epidemia.
11:52
Some think it's too many calories consumed.
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Algúns pensan que é o exceso de calorías.
11:55
Others think it's too much dietary fat.
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Outros cren que é moita graxa na dieta.
11:57
Others think it's too many refined grains and starches.
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Outros pensan que é o exceso de grans refinados e amidón.
12:01
But this team of multi-disciplinary,
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Pero este equipo multidisciplinario
12:03
highly skeptical and exceedingly talented researchers
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de investigadores altamente escépticos e de gran talento,
12:06
do agree on two things.
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puxéronse de acordo en dous puntos.
12:09
First, this problem is just simply too important
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En primeiro lugar, este problema é demasiado importante
12:12
to continue ignoring because we think we know the answer.
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para seguir ignorándoo, crendo que sabemos a resposta.
12:15
And two, if we're willing to be wrong,
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E dous, se estamos dispostos a estar equivocados,
12:18
if we're willing to challenge the conventional wisdom
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a desafiar a sabedoría convencional,
12:20
with the best experiments science can offer,
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coas mellores probas científicas,
12:23
we can solve this problem.
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podemos solucionar este problema.
12:26
I know it's tempting to want an answer right now,
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Sei que é tentador querer unha resposta inmediata,
12:29
some form of action or policy, some dietary prescription --
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algún tipo de acción ou política, algunha prescrición dietética
12:33
eat this, not that —
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--come isto, deixa isto--
12:35
but if we want to get it right,
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pero se queremos facelo ben,
12:37
we're going to have to do much more rigorous science
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imos ter que facer unha ciencia máis rigorosa
12:39
before we can write that prescription.
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antes de prescribir nada.
12:42
Briefly, to address this, our research program
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En resumo, para abordar isto,
12:44
is focused around three meta-themes, or questions.
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o noso programa de investigación está centrado arredor de tres piares.
12:47
First, how do the various foods we consume
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En primeiro lugar, como impacta o que consumimos
12:50
impact our metabolism, hormones and enzymes,
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no noso metabolismo, hormonas e encimas,
12:53
and through what nuanced molecular mechanisms?
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e a través de que matices nos mecanismos moleculares?
12:56
Second, based on these insights,
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En segundo lugar, en base a estas ideas,
12:58
can people make the necessary changes in their diets
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a xente pode facer os cambios necesarios nas súas dietas
13:01
in a way that's safe and practical to implement?
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de forma que sexa seguro e práctico facelo?
13:05
And finally, once we identify what safe
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E, finalmente, unha vez identificados os cambios prácticos e seguros
13:08
and practical changes people can make to their diet,
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13:11
how can we move their behavior in that direction
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como modificamos o noso comportamento
13:15
so that it becomes more the default
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para que isto se converta no corrente
13:17
rather than the exception?
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e non na excepción?
13:19
Just because you know what to do doesn't mean
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Porque xa saben que saber o que se debe facer
13:21
you're always going to do it.
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non sempre significa facelo.
13:23
Sometimes we have to put cues around people
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Ás veces hai que poñer pistas,
13:25
to make it easier, and believe it or not,
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2303
para facelo máis doado, e créano ou non,
13:27
that can be studied scientifically.
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3641
isto pode estudarse cientificamente.
13:31
I don't know how this journey is going to end,
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Non sei como vai rematar esta viaxe
13:33
but this much seems clear to me, at least:
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pero, polo menos para min, unha cousa está clara,
13:38
We can't keep blaming our overweight and diabetic patients
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Non podemos seguir culpando ós nosos pacientes con sobrepeso e diabéticos
13:43
like I did.
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como fixen eu.
13:45
Most of them actually want to do the right thing,
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A maioría deles queren facer o correcto,
13:48
but they have to know what that is,
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pero teñen que saber o que é,
13:51
and it's got to work.
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e así vai saír ben.
13:54
I dream of a day when our patients can
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Soño co día no que os pacientes,
13:59
shed their excess pounds
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poidan perder os quilos de máis,
14:01
and cure themselves of insulin resistance,
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e autocurarse da resistencia á insulina
14:03
because as medical professionals,
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grazas a que os profesionais médicos
14:06
we've shed our excess mental baggage
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1970
deixamos o noso exceso de ideas preconcibidas
14:08
and cured ourselves of new idea resistance sufficiently
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e autocurámonos da resistencia ás novas ideas
14:11
to go back to our original ideals:
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para volver ós nosos ideais orixinais:
14:15
open minds, the courage to throw out yesterday's ideas
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mente aberta, valor para tirar as ideas de onte
14:19
when they don't appear to be working,
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cando parecen non funcionar,
14:22
and the understanding that scientific truth isn't final,
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e entender que a verdade científica non é definitiva,
14:25
but constantly evolving.
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se non que evoluciona constantemente.
14:28
Staying true to that path will be better for our patients
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3292
Manterse fiel a ese camiño será mellor para os pacientes,
14:31
and better for science.
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e mellor para a ciencia.
14:35
If obesity is nothing more than a proxy
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2994
Se a obesidade non é máis que un representante
14:38
for metabolic illness,
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das enfermidades metabólicas,
14:40
what good does it do us to punish those with the proxy?
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5297
en que axuda castigar ao representante?
14:45
Sometimes I think back to that night in the E.R.
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Ás veces penso naquela noite en urxencias
14:49
seven years ago.
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de hai sete anos.
14:52
I wish I could speak with that woman again.
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Gustaríame poder falar con aquela muller de novo.
14:55
I'd like to tell her how sorry I am.
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Gustaríame dicirlle cando o sinto.
14:59
I'd say, as a doctor, I delivered
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Diríalle que, como médico lle dei os mellores coidados que puiden,
15:02
the best clinical care I could,
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15:05
but as a human being,
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pero que como ser humano a decepcionei.
15:09
I let you down.
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2408
15:11
You didn't need my judgment and my contempt.
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Non precisabas nin o meu xuízo nin o meu desprezo.
15:16
You needed my empathy and compassion,
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Precisabas empatía e compaixón
15:20
and above all else, you needed a doctor
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1995
e por riba de todo, precisabas un médico
15:22
who was willing to consider
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que estivese disposto a considerar
15:25
maybe you didn't let the system down.
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que se cadra non eras ti a que lle estaba fallando ó sistema.
15:28
Maybe the system, of which I was a part,
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Se cadra era o sistema, do que eu era parte,
15:31
was letting you down.
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o que che estaba fallando.
15:34
If you're watching this now,
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Se estás vendo isto,
15:36
I hope you can forgive me.
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Espero que me poidas perdoar.
15:41
(Applause)
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(Aplausos)
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