What is bipolar disorder? - Helen M. Farrell

13,744,802 views ・ 2017-02-09

TED-Ed


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What is bipolar disorder?
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The word bipolar means two extremes.
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For the many millions experiencing bipolar disorder around the world,
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life is split between two different realities -
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elation and depression.
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Although there are many variations of bipolar disorder,
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let's consider a couple.
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Type 1 has extreme highs alongside the lows,
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while Type 2 involves briefer, less extreme periods of elation
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interspersed with long periods of depression.
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For someone seesawing between emotional states,
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it can feel impossible to find the balance necessary to lead a healthy life.
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Type 1's extreme highs are known as manic episodes,
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and they can make a person range from feeling irritable to invincible.
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But these euphoric episodes exceed ordinary feelings of joy,
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causing troubling symptoms like racing thoughts,
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sleeplessness,
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rapid speech,
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impuslive actions,
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and risky behaviors.
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Without treatment, these episodes become more frequent,
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intense,
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and take longer to subside.
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The depressed phase of bipolar disorder manifests in many ways -
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a low mood,
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dwindling interest in hobbies,
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changes in appetite,
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feeling worthless or excessively guilty,
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sleeping either too much or too little,
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restlessness or slowness,
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or persistent thoughts of suicide.
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Worldwide, about one to three percent of adults
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experience the broad range of symptoms that indicate bipolar disorder.
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Most of those people are functional, contributing members of society,
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and their lives, choices, and relationships
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aren't defined by the disorder,
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but still, for many, the consequences are serious.
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The illness can undermine educational and professional performance,
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relationships,
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financial security,
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and personal safety.
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So what causes bipolar disorder?
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Researchers think a key player is the brain's intricate wiring.
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Healthy brains maintain strong connections between neurons
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thanks to the brain's continuous efforts to prune itself
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and remove unused or faulty neural connections.
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This process is important because our neural pathways serve as a map
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for everything we do.
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Using functional magnetic resonance imaging,
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scientists have discovered that the brain's pruning ability is disrupted
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in people with bipolar disorder.
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That means their neurons go haywire
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and create a network that's impossible to navigate.
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With only confusing signals as a guide,
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people with bipolar disorder develop abnormal thoughts and behaviors.
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Also, psychotic symptoms,
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like disorganized speech and behavior,
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delusional thoughts,
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paranoia,
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and hallucinations
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can emerge during extreme phases of bipolar disorder.
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This is attributed to the overabundance of a neurotransmitter called dopamine.
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But despite these insights, we can't pin bipolar disorder down to a single cause.
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In reality, it's a complex problem.
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For example, the brain's amygdala is involved in thinking,
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long-term memory,
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and emotional processing.
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In this brain region, factors as varied as genetics and social trauma
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may create abnormalities and trigger the symptoms of bipolar disorder.
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The condition tends to run in families,
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so we do know that genetics have a lot to do with it.
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But that doesn't mean there's a single bipolar gene.
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In fact, the likelihood of developing bipolar disorder
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is driven by the interactions between many genes
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in a complicated recipe we're still trying to understand.
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The causes are complex,
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and consequently, diagnosing and living with bipolar disorder is a challenge.
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Despite this, the disorder is controllable.
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Certain medications like lithium can help manage risky thoughts and behaviors
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by stabilizing moods.
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These mood stabilizing medications work by decreasing abnormal activity in the brain,
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thereby strengthening the viable neural connections.
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Other frequently used medications include antipsychotics,
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which alter the effects of dopamine,
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and electroconvulsive therapy,
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which works like a carefully controlled seizure in the brain,
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is sometimes used as an emergency treatment.
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Some bipolar patients reject treatment
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because they're afraid it will dim their emotions
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and destroy their creativity.
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But modern psychiatry is actively trying to avoid that.
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Today, doctors work with patients on a case-by-case basis
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to administer a combination of treatments and therapies
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that allows them to live to their fullest possible potential.
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And beyond treatment, people with bipolar disorder can benefit
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from even simpler changes.
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Those include regular exercise,
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good sleep habits,
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and sobriety from drugs and alcohol,
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not to mention the acceptance and empathy of family and friends.
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Remember, bipolar disorder is a medical condition,
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not a person's fault,
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or their whole identity,
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and it's something that can be controlled
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through a combination of medical treatments doing their work internally,
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friends and family fostering acceptance and understanding on the outside,
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and people with bipolar disorder empowering themselves
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to find balance in their lives.
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