What causes cavities? - Mel Rosenberg

6,536,774 views ・ 2016-10-17

TED-Ed


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翻译人员: Lipeng Chen 校对人员: Gabriella Hu
00:07
When a team of archaeologists recently came across
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当一群考古学家最近发掘出
00:09
some 15,000 year-old human remains,
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将近15000年前的人类骸骨时,
00:12
they made an interesting discovery.
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他们有了一个有趣的发现:
00:15
The teeth of those ancient humans were riddled with holes.
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这些远古人的牙齿上有许多蛀洞。
00:19
Their cavities were caused by the same thing that still plagues us today,
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他们蛀牙的罪魁祸首和今天折磨我们的东西一样,
00:23
specific tiny microbes that live in our mouths.
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那就是生活在我们口中的某些细菌。
00:28
These microbes are with us soon after birth.
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这些细菌从出生时就开始伴随着我们。
00:30
We typically pick them up as babies from our mothers' mouths.
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一般而言,它们是从母亲的口中传给孩子的。
00:34
And as our teeth erupt,
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当我们的牙齿开始生长时,
00:35
they naturally begin to accumulate communities of bacteria.
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它们便开始形成菌落。
00:39
Depending on what we eat,
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我们所吃的食物
00:41
and specifically how much sugar we consume,
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和我们所摄入的糖分,
00:43
certain microbes can overpopulate and cause cavities.
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可以使得某些细菌过度增殖并形成龋齿。
00:48
Diets high in sugary foods cause an explosion of bacteria
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高糖饮食会导致我们口中
00:52
called mutans streptococci in our mouths.
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一种叫做"变形链球菌"的细菌爆发式的增长。
00:55
Like humans, these microorganisms love sugar,
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就像人类一样,这些微生物喜欢糖类,
00:58
using it as a molecular building block and energy source.
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并将糖作为生长的基石和能量的来源。
01:03
As they consume it,
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当细菌消耗糖类时,
01:04
the bacteria generate byproducts in the form of acids,
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它们会产生一种酸性的副产品,
01:07
such as lactic acid.
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比如"乳酸"。
01:09
Mutans streptococci are resistant to this acid,
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"变形链球菌"可以免疫乳酸的腐蚀,
01:13
but unfortunately, our teeth aren't.
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然而不幸的是,我们的牙齿并不可以。
01:16
While each human tooth is coated in a hardy, protective layer of enamel,
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尽管我们每个人的牙齿上都有一层质 地坚硬,可以起到保护作用的"牙釉质",
01:20
it's no match for acid.
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但是这仍不是酸的对手。
01:22
That degrades the armor over time, leaching away its calcium minerals.
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随着时间的推移,酸会侵蚀这层盔甲,溶解其中的钙元素。
01:28
Gradually, acid wears down a pathway for bacteria
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渐渐地,酸会为细菌侵蚀出一条通道,
01:31
into the tooth's secondary layer called the dentin.
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直达被称作"牙本质"的牙齿内层。
01:35
Since blood vessels and nerves in our teeth are enclosed deep within,
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因为牙齿的血管和神经都被保护在最深处,
01:40
at this stage, the expanding cavity doesn't hurt.
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在这个阶段,逐渐扩大的龋齿并不会造成痛感。
01:43
But if the damage extends beyond the dentin,
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但是一当细菌继续侵蚀,
01:46
the bacterial invasion progresses
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超过"牙本质"的范围,
01:48
causing excruciating pain as the nerves become exposed.
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神经就会被暴露,同时形成强烈痛感。
01:52
Without treatment, the whole tooth may become infected
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如果不加治疗,整颗牙齿就会受到感染
01:55
and require removal
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并且需要拔除,
01:57
all due to those sugar-loving bacteria.
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这都是由那些好糖类细菌导致的。
02:00
The more sugar our food contains,
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摄入食物中的糖分越多,
02:02
the more our teeth are put at risk.
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牙齿受到的威胁就越大。
02:04
Those cavemen would hardly have indulged in sugary treats, however,
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然而,那些山顶洞人几乎不会饕餮甜食盛宴,
02:09
so what caused their cavities?
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那么他们的龋齿是什么造成的呢?
02:11
In meat-heavy diets, there would have been a low-risk of cavities developing
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在多肉的饮食中,形成龋齿的风险较小,
02:16
because lean meat contains very little sugar,
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因为瘦肉中包含很少的糖分。
02:19
but that's not all our early human ancestors ate.
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但是我们的祖先不仅仅只吃瘦肉,
02:22
Cavemen would also have consumed root vegetables, nuts, and grains,
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山顶洞人还会吃根类蔬菜,坚果和谷物,
02:27
all of which contain carbohydrates.
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这些食物都包含碳水化合物。
02:29
When exposed to enzymes in the saliva,
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当碳水化合物暴露在唾液中酶的环境时,
02:32
carbohydrates get broken down into simpler sugars,
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它们便会被分解更为简单的糖,
02:35
which can become the fodder for those ravenous mouth bacteria.
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这为那些贪婪的细菌提供了养分。
02:40
So while ancient humans did eat less sugar compared to us,
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所以尽管我们的祖先相较我们摄入了更少的糖分,
02:44
their teeth were still exposed to sugars.
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但他们的牙齿仍暴露在糖分之中。
02:47
That doesn't mean they were unable to treat their cavities, though.
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虽然如此,这并不代表他们不能治疗龋齿。
02:50
Archaeological remains show that about 14,000 years ago,
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考古遗迹显示在约14000年前,
02:54
humans were already using sharpened flint to remove bits of rotten teeth.
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人类已经会使用磨尖的燧石去除烂牙。
03:00
Ancient humans even made rudimentary drills
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远古人甚至做了最原始的钻头
03:02
to smooth out the rough holes left behind
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用于磨平留下的粗糙的龋洞,
03:05
and beeswax to plug cavities, like modern-day fillings.
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并将蜂蜡注入蛀孔,就如今天的填充物一样。
03:10
Today, we have much more sophisticated techniques and tools,
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如今,我们有了更加成熟的技术和工具,
03:13
which is fortunate because we also need to contend with our more damaging,
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这是非常幸运的,因为我们需要面对更具破坏性的
03:17
sugar-guzzling ways.
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更多糖分的饮食。
03:20
After the Industrial Revolution, the human incidence of cavities surged
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工业革命后,人类龋齿发生率飙升,
03:24
because suddenly we had technological advances
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这是因为突然之间我们有了更加先进的技术
03:27
that made refined sugar cheaper and accessible.
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使得精炼糖变得更加便宜和易得。
03:31
Today, an incredible 92% of American adults have had cavities in their teeth.
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今天,92%的美国成年人有龋齿问题,难以置信。
03:37
Some people are more susceptible to cavities due to genes
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某些人由于基因更易形成龋齿,
03:39
that may cause certain weaknesses, like softer enamel,
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这些基因会导致如更软的"牙釉质"等问题,
03:42
but for most, high sugar consumption is to blame.
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但是对于大多数人而言,高糖的摄入才是罪魁祸首。
03:46
However, we have developed other ways of minimizing cavities
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但是,我们已经发展出了
03:50
besides reducing our intake of sugar and starch.
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降低糖类和淀粉摄入之外减少龋齿的办法。
03:53
In most toothpastes and many water supplies,
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在大部分的牙膏和自来水中,
03:56
we use tiny amounts of fluoride.
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我们添加了少量的氟化物。
03:59
That strengthens teeth and encourages the growth of enamel crystals
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氟化物可以增强牙齿并促使牙釉质生长
04:03
that build up a tooth's defenses against acid.
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以抵抗酸的侵蚀。
04:06
When cavities do develop,
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当龋齿已经产生时,
04:07
we use tooth fillings to fill and close off the infected area,
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我们利用牙齿填充物去填补并封闭被感染区域,
04:11
preventing them from getting worse.
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防止它们朝着更坏的方向发展。
04:13
The best way to avoid a cavity is still cutting down on sugar intake
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然而,预防龋齿的最佳方式仍是降低糖分摄入,
04:18
and practicing good oral hygiene
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形成良好的口腔卫生,
04:20
to get rid of the bacteria and their food sources.
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以消除细菌和它们的食物来源。
04:23
That includes regular tooth brushing,
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这包含日常的刷牙,
04:24
flossing,
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剔牙,
04:25
and avoiding sugary,
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避免摄入糖类
04:27
starchy,
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04:27
and sticky foods that cling to your teeth between meals.
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淀粉
和在各餐之间会附着于牙齿上的粘性食物。
04:31
Gradually, the population of sugar-loving microbes in your mouth will decline.
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渐渐地,口腔中的好糖类细菌便会减少。
04:36
Unlike the cavemen of yesteryear,
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和以前的山顶洞人不同,
04:38
today we have the knowledge required to avert a cavity calamity.
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今天的我们拥有更多预防龋齿的知识。
04:41
We just need to use it.
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我们只需运用它。
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