Why is meningitis so dangerous? - Melvin Sanicas

3,007,306 views ・ 2018-11-19

TED-Ed


Please double-click on the English subtitles below to play the video.

Prevodilac: Aleksandar Bošnjak Lektor: Ivana Krivokuća
00:06
In 1987, tens of thousands of people
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Godine 1987, desetine hiljada ljudi
00:09
gathered in Saudi Arabia for the annual Hajj pilgrimage.
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okupilo se u Saudijskoj Arabiji za godišnji hadžiluk.
00:14
But what started out as a celebration led to a health crisis:
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Ono što je počelo kao proslava dovelo je do zdravstvene krize:
00:18
just a few days after the pilgrimage,
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samo nekoliko dana nakon hadžiluka,
00:20
more than 2,000 cases of meningitis broke out
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pojavilo se više od 2000 slučajeva meningitisa
00:24
spreading across Saudi Arabia and the rest of the world.
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koji se širio po Saudijskoj Arabiji i po ostatku sveta.
00:28
The outbreak was so fierce
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Izbijanje je bilo tako žestoko
00:30
that it was believed to have sparked a wave of deadly meningitis epidemics
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da se verovalo da je podstaklo talas smrtonosne epidemije meningitisa
00:34
that ultimately infected tens of thousands of people worldwide.
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od kojeg se naposletku inficiralo desetine hiljada ljudi širom sveta.
00:40
Meningitis is the inflammation of the meninges,
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Meningitis je zapaljenje moždanih opni,
00:43
three tissue layers responsible for protecting the brain and spinal cord.
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tri sloja tkiva koja su odgovorna za zaštitu mozga i kičmene moždine.
00:48
What makes meningitis so dangerous compared to other diseases
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Ono što čini meningitis toliko opasnim u poređenju sa drugim bolestima
00:52
is the sheer speed with which it invades a person’s body.
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je brzina kojom napada nečije telo.
00:56
In the worst cases, it causes death within a day.
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U najgorim slučajevima prouzrokuje smrt u roku od jednog dana.
00:59
Fortunately, that’s rare for patients who receive early medical treatment.
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Na sreću, to je retko kod pacijenata koji rano prime terapiju.
01:04
The disease primarily comes in three forms:
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Bolest uglavnom dolazi u tri oblika:
01:07
fungal, viral, and bacterial-- the last being the most deadly by far,
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gljivičnom, virusnom i bakterijskom - poslednji je najsmrtonosniji,
01:12
and what we’ll focus on.
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i na njega ćemo se fokusirati.
01:15
People usually contract bacterial meningitis by breathing in
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Ljudi uglavnom pokupe bakterijiski meningitis tako što udahnu
01:18
tiny particles of mucus and saliva that spray into the air
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male čestice sluzi i pljuvačke koji se rasrprše u vazduhu
01:22
when an infected person sneezes or coughs.
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kad zaražena osoba kije ili kašlje.
01:26
It can also be transmitted through kissing,
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Može se preneti i ljubljenjem,
01:28
or sharing cigarettes, toothbrushes or utensils.
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deljenjem cigareta, četikica za zube ili pribora za jelo.
01:32
Some people can be infected and carry the disease
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Neki ljudi mogu biti zaraženi i da imaju bolest
01:35
without showing symptoms or getting sick,
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a da ne ispolje simptome niti se razbole,
01:38
which helps the disease spread quickly to others.
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što pomaže bolesti da se brže širi do drugih.
01:41
Once the bacteria enter the nose, mouth, and throat,
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Onda kad bakterije uđu u nos, usta i grlo,
01:45
they cross the surrounding membranes and enter the bloodstream.
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one pređu okolne membrane i uđu u krvotok.
01:48
From there, bacteria have rapid access to the body’s tissues
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Odatle bakterije imaju ubrzan pristup telesnim tkivima,
01:53
--including a membrane called the blood-brain barrier.
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uključujući i membranu zvanu krvno-moždana barijera.
01:56
This is made of a tight mesh of cells which separate blood vessels from the brain,
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Ona je napravljena od tesne mreže ćelija koje odvajaju krvne sudove od mozga,
02:01
and block everything except for a specific set of particles,
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i blokiraju sve osim specifičnih čestica
02:05
including water molecules and some gases.
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koje uključuju molekule vode i neke gasove.
02:09
But in ways that scientists are still trying to understand,
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Na načine koje naučnici još pokušavaju da shvate,
02:12
meningitis bacteria can trick the barrier into letting them through.
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bakterija meningitisa može da obmane barijeru i da prođe kroz nju.
02:17
Inside the brain, the bacteria swiftly infect the meninges.
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Unutar mozga, bakterije brzo inficiraju moždane opne.
02:21
This triggers inflammation as the body’s immune response kicks into overdrive,
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Ovo pokreće zapaljenje dok imuni sistem ubrzava svoj rad,
02:26
bringing on fever and intense headaches.
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što dovodi do temperature i jakih glavobolja.
02:29
As swelling in the meninges worsens, the neck begins to stiffen.
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Kako se otok u moždanim opnama pogoršava, vrat počinje da se koči.
02:33
Swelling in the brain disrupts its normal function--
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Otok u mozgu remeti njegovo normalno funkcionisanje,
02:35
causing symptoms like hearing loss and extreme light sensitivity.
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prouzrokujući gubitak sluha i ekstremnu osetljivost na svetlost.
02:40
As pressure increases in the cranium, it may also make the person confused--
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Kako se pritisak u lobanji povećava, može i da dovede do zbunjenosti osobe,
02:45
one of the hallmarks of the disease.
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što je jedno od obeležja ove bolesti.
02:47
A few hours in, the rapidly multiplying bacteria start to release toxins,
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Nakon nekoliko sati,
ove bakterije koje se brzo razmnožavaju počinju da ispuštaju otrove,
02:52
leading to septicemia, also known as blood poisoning.
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čime dovode do sepse, takođe poznate i kao trovanje krvi.
02:57
This breaks down blood vessels,
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Ovo razbija krvne sudove,
02:59
letting blood seep out and form what starts out looking like a rash,
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dopuštajući krvi da curi napolje i da formira nešto što izgleda kao osip,
03:03
and evolves into big discoloured blots beneath the skin.
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a potom se razvija u velike mrlje ispod kože.
03:08
At the same time, these toxins burn through oxygen in the blood,
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U isto vreme, ovi otrovi sagorevaju kiseonik u krvi,
03:12
reducing the amount that gets to major organs like the lungs and kidneys.
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smanjujući količinu koja dospeva do glavnih organa poput pluća i bubrega.
03:17
That increases the chance of organ shut down
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To povećava šansu da organi prestanu sa radom,
03:20
--and alongside spreading septicemia, threatens death.
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a pored širenja sepse, preti smrt.
03:24
That all sounds scary, but doctors are so good at treating meningitis
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Sve to zvuči strašno, ali doktori su toliko dobri u lečenju meningitisa
03:29
that a visit to the hospital can drastically reduce an adult’s risk of dying from it.
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da poseta bolnici može drastično smanjiti rizik da odrasla osoba umre od njega.
03:34
The longer it’s left untreated, though,
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Što je duže nelečen,
03:36
the more likely it will lead to lasting damage.
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to je veća šansa da će doći do trajnih posledica.
03:39
If declining oxygen levels cause cell death in extreme parts of the body
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Ako opadajući nivoi kiseonika prouzrokuju smrt ćelija u ekstremitetima -
03:43
--like fingers, toes, arms and legs-- the risk of amputation goes up.
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u prstima, rukama i nogama - rizik od amputacije se povećava.
03:49
And if bacterial toxins accumulate in the brain and trigger cell death,
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A ako se otrovi bakterija nagomilaju u mozgu i pokrenu smrt ćelija,
03:54
meningitis could also cause long-term brain damage and memory loss.
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meningitis može prouzrokovati dugoročno oštećenje mozga i gubitak pamćenja.
03:58
So fast treatment, or better yet, prevention, is critical.
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Brza terapija, ili još bolje, prevencija, je presudna.
04:03
That's why most countries have vaccines that defend against the disease
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Zato većina država ima vakcine koje štite od bolesti
04:07
in its deadliest forms.
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u njenom najsmrtonosnijem obliku.
04:09
Those are usually given to the people who are most at risk--like young children,
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One se uglavnom daju ljudima koji su najviše pod rizikom -
deci na ranom uzrastu,
04:13
people with weak immune systems, or people who gather in large groups
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ljudima sa slabim imunim sistemima ili onima koji se okupljaju u velike grupe
04:17
where an outbreak of meningitis could potentially happen.
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gde bi meningitis potencijalno mogao da izbije.
04:21
In addition to those gatherings,
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Pored takvih okupljanja,
04:23
meningitis is most common in a region called the meningitis belt
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meningitis je najčešći u regiji zvanoj „pojas meningitisa”
04:27
that stretches across Africa, though cases do happen all over the world.
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koji se prostire duž Afrike, mada slučajevi se dešavaju u celom svetu.
04:32
If you’re concerned that you or someone you know may have meningitis,
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Ako ste zabrinuti da vi ili neko koga poznajete možda ima meningitis,
04:35
get to the doctor as soon as possible;
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idite kod lekara što je pre moguće;
04:38
quick action could save your life.
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brzo delovanje bi moglo da vam spasi život.
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