Nancy Kanwisher: A neural portrait of the human mind

185,297 views ・ 2014-10-02

TED


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00:00
Translator: Joseph Geni Reviewer: Madeleine Aronson
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翻译人员: Steven Dang 校对人员: Qiwen Lu
00:12
Today I want to tell you
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今天我想告诉大家一个
00:13
about a project being carried out
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由全世界各地科学家一起完成的项目。
00:15
by scientists all over the world
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这个项目希望用神经系统图景
00:18
to paint a neural portrait of the human mind.
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来描绘人类思想。
00:21
And the central idea of this work
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这一项目的中心论点,
00:23
is that the human mind and brain
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就是人类的思想和大脑
00:25
is not a single, general-purpose processor,
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不是一个独立、普通的处理器,
00:28
but a collection of highly specialized components,
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而是一个许多高度专业化的组分的集合。
00:31
each solving a different specific problem,
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其中的每一个组分都专门处理不同的问题,
00:34
and yet collectively making up
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最终这些组分合在一起,
00:37
who we are as human beings and thinkers.
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成就了我们人类,思考者们。
00:41
To give you a feel for this idea,
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为了让你们更好地感受这一理论,
00:43
imagine the following scenario:
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请想象一下接下来的场景:
00:45
You walk into your child's day care center.
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你走进了你孩子的托管中心。
00:47
As usual, there's a dozen kids there
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像往常一样,那里有许多的孩子
00:50
waiting to get picked up,
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等待着被家长接走。
00:51
but this time,
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但是在这时,
00:53
the children's faces look weirdly similar,
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这些孩子们的脸庞看起来奇怪地相似,
00:56
and you can't figure out which child is yours.
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你无法分辨出哪一个才是你的孩子。
00:59
Do you need new glasses?
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你是需要一副新眼镜吗?
01:00
Are you losing your mind?
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你是精神错乱了吗?
01:02
You run through a quick mental checklist.
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你的脑海中快速地过了一遍自己的精神状况清单
01:05
No, you seem to be thinking clearly,
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不,你看起来脑子很清楚,
01:07
and your vision is perfectly sharp.
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你的视力也十分锐利。
01:09
And everything looks normal
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所有事都看起来非常正常,
01:11
except the children's faces.
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除了那些孩子们的脸。
01:13
You can see the faces,
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你看着这些脸庞,
01:15
but they don't look distinctive,
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可它们竟没什么差别,
01:17
and none of them looks familiar,
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而且没有一张看起来熟悉。
01:18
and it's only by spotting an orange hair ribbon
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你只是因为发现了一只橘色发带,
01:21
that you find your daughter.
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才得以找到你的女儿。
01:23
This sudden loss of the ability to recognize faces
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这种对于认脸能力的突然缺失,
01:26
actually happens to people.
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经常在人们身上发生。
01:28
It's called prosopagnosia,
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这种现象叫做面容失认症,
01:30
and it results from damage
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它是由脑部一个特定部分损伤
01:31
to a particular part of the brain.
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而引起的。
01:33
The striking thing about it
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这种现象最显著的特征就是,
01:35
is that only face recognition is impaired;
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只有认脸的能力被损害了,
01:37
everything else is just fine.
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其他的一切都看起来很正常。
01:40
Prosopagnosia is one of many surprisingly specific
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面容失认证是许多很特别的
01:44
mental deficits that can happen after brain damage.
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脑部损伤产生的精神缺陷的其中一种。
01:48
These syndromes collectively
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这些症状一起
01:49
have suggested for a long time
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在很早之前就显示出
01:52
that the mind is divvied up into distinct components,
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人的头脑是被均分成了不同的组分的。
01:55
but the effort to discover those components
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但是研究这些组分的努力,
01:58
has jumped to warp speed
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却因为大脑成像技术,
01:59
with the invention of brain imaging technology,
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特别是MRI技术的发明
02:02
especially MRI.
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而快速发展,进展迅猛。
02:05
So MRI enables you to see internal anatomy
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所以MRI让你能够很清晰地
02:08
at high resolution,
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看到内在的结构。
02:10
so I'm going to show you in a second
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我接下来会给你们看看
02:11
a set of MRI cross-sectional images
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一系列常见物体的
02:15
through a familiar object,
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MRI跨区域影像。
02:16
and we're going to fly through them
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我们将快速地翻动图片,
02:17
and you're going to try to figure out what the object is.
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让你们试着猜猜那些是什么物体。
02:20
Here we go.
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接下来开始了。
02:24
It's not that easy. It's an artichoke.
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这个不太容易。这是一朵菊芋。
02:26
Okay, let's try another one,
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试试另外一个。
02:27
starting from the bottom and going through the top.
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从底部开始向顶部移动。
02:32
Broccoli! It's a head of broccoli.
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花椰菜!这一一朵花椰菜的顶部。
02:33
Isn't it beautiful? I love that.
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它很漂亮,不是吗?我很喜欢。
02:35
Okay, here's another one. It's a brain, of course.
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这里还有一个。当然,这是大脑。
02:38
In fact, it's my brain.
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实际上,这是我的大脑。
02:39
We're going through slices through my head like that.
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我们在一部分一部分看透我的大脑。
02:41
That's my nose over on the right, and now
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刚才右边的是我的鼻子,
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we're going over here, right there.
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现在我们已经到了这里,就是这里。
02:46
So this picture's nice, if I do say so myself,
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要我说,这张照片挺好,
02:51
but it shows only anatomy.
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可是它只展示了内部构造。
02:53
The really cool advance with functional imaging
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功能性影像最酷的进步在于
02:55
happened when scientists figured out how to make
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科学家找到制作出
02:57
pictures that show not just anatomy but activity,
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不仅展示构造,更展示内部活动的图片。
03:00
that is, where neurons are firing.
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也就是神经元的活动。
03:03
So here's how this works.
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那么接下来是这项技术的原理。
03:04
Brains are like muscles.
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大脑就像肌肉,
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When they get active,
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当大脑变得活跃时,
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they need increased blood flow to supply that activity,
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他们需要更多的血液来支撑这样的活动。
03:10
and lucky for us, blood flow control to the brain is local,
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正好,控制大脑的血液就存在与大脑中。
03:14
so if a bunch of neurons, say, right there
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所以比如说这儿的一些神经元
03:16
get active and start firing,
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变得活跃,开始传输信号,
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then blood flow increases just right there.
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接下来这儿的血液流量就会增加。
03:20
So functional MRI picks up on that blood flow increase,
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所以功能性MRI专门探测血流量的增加,
03:24
producing a higher MRI response
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当神经活动增强时,
03:26
where neural activity goes up.
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就产生更高的MRI回应。
03:29
So to give you a concrete feel
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为了让你们更直观的感受
03:30
for how a functional MRI experiment goes
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功能性MRI实验如何运作,
03:33
and what you can learn from it
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还有你们能从中学到什么,学不到什么,
03:34
and what you can't,
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让我给你们讲一讲我做过的第一个研究。
03:36
let me describe one of the first studies I ever did.
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我们想要弄清楚大脑中到底有没有
03:39
We wanted to know if there was a special part of the brain for recognizing faces,
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一个特定的部分帮助人们分辨脸庞。
03:43
and there was already reason to think there might be such a thing
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基于我先前提到的面容失认症的现象,
03:46
based on this phenomenon of prosopagnosia
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我们有理由相信,
03:48
that I described a moment ago,
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大脑中这样的部位确实存在。
03:50
but nobody had ever seen that part of the brain
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但是没有人在常人的大脑中
03:52
in a normal person,
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看见过这个部位。
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so we set out to look for it.
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所以我们开始寻找那个部位。
03:56
So I was the first subject.
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我是第一个实验对象。
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I went into the scanner, I lay on my back,
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我走进扫描仪,平躺下。
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I held my head as still as I could
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我尽量让我的头保持静止
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while staring at pictures of faces like these
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看着像这些照片上的脸庞,
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and objects like these
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和像这些照片上的物体。
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and faces and objects for hours.
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人脸,物体,重复了几个小时。
04:15
So as somebody who has pretty close to the world record
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作为一个已经接近
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of total number of hours spent inside an MRI scanner,
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在MRI扫描仪内待的时间的世界纪录的人
04:22
I can tell you that one of the skills
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我能告诉你,MRI研究中其中一个
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that's really important for MRI research
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重要的技巧就是
04:26
is bladder control.
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憋尿的本领。
04:28
(Laughter)
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(笑声)
04:29
When I got out of the scanner,
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我走出扫描仪后,
04:31
I did a quick analysis of the data,
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我快速分析了那些数据,
04:33
looking for any parts of my brain
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寻找有没有任何大脑的部分
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that produced a higher response when I was looking at faces
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在我看人脸时产生了比我看物体时
04:38
than when I was looking at objects,
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更高的反应。
04:39
and here's what I saw.
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这是我看到的数据。
04:42
Now this image looks just awful by today's standards,
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这些图像以今天的标准来看很糟,
04:45
but at the time I thought it was beautiful.
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但在当时我看来,它很漂亮。
04:48
What it shows is that region right there,
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它展示了这里的一块区域,
04:50
that little blob,
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这里的一小团。
04:51
it's about the size of an olive
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大概和一颗橄榄差不多大。
04:53
and it's on the bottom surface of my brain
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这部分在我大脑的底层,
04:55
about an inch straight in from right there.
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大概从这里向里一英寸。
04:58
And what that part of my brain is doing
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当我看到人脸的时候
05:01
is producing a higher MRI response,
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我的大脑的这一部分
05:04
that is, higher neural activity,
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比我看到物体的时候
05:06
when I was looking at faces
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产生了更高的MRI反应,
05:07
than when I was looking at objects.
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也就是更高的神经活动。
05:10
So that's pretty cool,
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这个结果令人振奋,
05:11
but how do we know this isn't a fluke?
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但我们怎么能知道这是不是偶然呢?
05:13
Well, the easiest way
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当然,最简单的方法,
05:15
is to just do the experiment again.
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就是重复做这个实验。
05:17
So I got back in the scanner,
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所以我回到了扫描仪里。
05:18
I looked at more faces and I looked at more objects
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我盯着更多的人脸和更多的物体,
05:21
and I got a similar blob,
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也得到了相似的结果。
05:23
and then I did it again
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我又重复,
05:25
and I did it again
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又重复
05:27
and again and again,
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重复再重复。
05:30
and around about then
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直到那时,
05:31
I decided to believe it was for real.
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我才决定相信,实验结果是正确的。
05:34
But still, maybe this is something weird about my brain
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但是,仍然有可是事我的大脑有些不同寻常。
05:38
and no one else has one of these things in there,
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有可能其他人都没有我那种问题。
05:40
so to find out, we scanned a bunch of other people
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为了证实实验结果,我们又扫描了其他很多人的大脑。
05:43
and found that pretty much everyone
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最后发现几乎每个人的大脑里,
05:45
has that little face-processing region
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在相似的位置上,
05:47
in a similar neighborhood of the brain.
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都有那一小块识别人脸的区域。
05:50
So the next question was,
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那么下一个问题来了,
05:52
what does this thing really do?
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这个区域到底做些什么?
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Is it really specialized just for face recognition?
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它是专门只用来识别人脸吗?
05:57
Well, maybe not, right?
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或许有可能不是这样的。
05:58
Maybe it responds not only to faces
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也许它不仅仅对人脸有反应,
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but to any body part.
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也会对任何的人体部位有反应。
06:02
Maybe it responds to anything human
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也许它会对任何与人类相关的
06:05
or anything alive
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或者任何生物
06:07
or anything round.
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或者任何圆形的东西起反应。
06:08
The only way to be really sure that that region
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为了确定那块小区域
06:10
is specialized for face recognition
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是专门用来识别人脸的,
06:13
is to rule out all of those hypotheses.
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必须排除掉刚才提到的所有假设。
06:15
So we spent much of the next couple of years
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所以我们花了接下来的好几年,
06:18
scanning subjects while they looked at lots
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在实验对象看着许多不同种类图像时
06:20
of different kinds of images,
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扫描他们的大脑。
06:21
and we showed that that part of the brain
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我们证明了大脑的那一区域
06:23
responds strongly when you look at
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在你看着任何种类的脸的任何图像时
06:25
any images that are faces of any kind,
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会起强烈的反应。
06:29
and it responds much less strongly
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当你看的是非脸庞的图像时,
06:31
to any image you show that isn't a face,
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那块区域的反应会弱很多
06:34
like some of these.
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就像这些图像。
06:35
So have we finally nailed the case
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那么我们是不是已经确定
06:37
that this region is necessary for face recognition?
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脸庞识别必须依靠这一区域了呢?
06:41
No, we haven't.
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不,我们没有。
06:42
Brain imaging can never tell you
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大脑图像永远不能告诉你
06:44
if a region is necessary for anything.
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任何东西是否依靠一块区域。
06:46
All you can do with brain imaging
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大脑图像能让你做的
06:48
is watch regions turn on and off
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只有看着当人们想着不同东西时,
06:50
as people think different thoughts.
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他们大脑各个区域变得活跃或不活跃。
06:52
To tell if a part of the brain is necessary for a mental function,
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为了确定大脑的一部分是否对于精神功能至关重要,
06:55
you need to mess with it and see what happens,
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你需要干扰那一部分的功能,看看会发生什么。
06:58
and normally we don't get to do that.
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一般我们无法那样做。
07:00
But an amazing opportunity came about
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但是,一个绝好的机会出现了。
07:03
very recently when a couple of colleagues of mine
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最近我的一些同事
07:05
tested this man who has epilepsy
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测试了这个在病床上躺着的
07:08
and who is shown here in his hospital bed
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患有癫痫的男人。
07:11
where he's just had electrodes placed
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在他大脑的表层
07:12
on the surface of his brain
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刚刚被装上了电极,
07:14
to identify the source of his seizures.
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来弄清他癫痫发作的来源。
07:17
So it turned out by total chance
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结果是非常碰巧地,
07:20
that two of the electrodes
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其中两个电极
07:22
happened to be right on top of his face area.
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正好在他面部区域的顶端。
07:25
So with the patient's consent,
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所以经过了患者的同意,
07:27
the doctors asked him what happened
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医生问他,当电极刺激大脑那个区域时,
07:30
when they electrically stimulated that part of his brain.
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发生了什么。
07:34
Now, the patient doesn't know
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那时,患者还不知道
07:35
where those electrodes are,
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那些电极在哪儿,
07:37
and he's never heard of the face area.
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他也从未听说过面部区域。
07:39
So let's watch what happens.
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让我们来看看发生了什么。
07:41
It's going to start with a control condition
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一开始,会有一个控制条件。
07:43
that will say "Sham" nearly invisibly
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当没有电流被输送时
07:45
in red in the lower left,
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左下角会出现一个几乎看不见的
07:47
when no current is delivered,
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红色字“假装的”。
07:49
and you'll hear the neurologist speaking to the patient first. So let's watch.
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你会听到神经学家对患者讲话。我们来看看吧。
07:53
(Video) Neurologist: Okay, just look at my face
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(视频)神经学家:好的,看着我的脸。
07:55
and tell me what happens when I do this.
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当我这样做的时候告诉我发生了些什么。
07:59
All right?
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好吗?
08:00
Patient: Okay.
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患者:好的。
08:02
Neurologist: One, two, three.
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神经学家:一,二,三。
08:07
Patient: Nothing. Neurologist: Nothing? Okay.
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患者:什么也没有发生
08:10
I'm going to do it one more time.
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神经学家:什么也没有?好的,我会再做一次。
08:12
Look at my face.
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看着我的脸。
08:15
One, two, three.
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一,二,三。
08:20
Patient: You just turned into somebody else.
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患者:你变成了另外一个人。
08:23
Your face metamorphosed.
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你的脸变形了。
08:25
Your nose got saggy, it went to the left.
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你的鼻子变得松弛,偏向了左边。
08:28
You almost looked like somebody I'd seen before,
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你看起来就像一个我以前见过的人,
08:31
but somebody different.
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但其实又不是。
08:34
That was a trip.
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那是幻觉
08:36
(Laughter)
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(笑声)
08:39
Nancy Kanwisher: So this experiment —
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Nancy Kanwisher:那么这个实验—
08:41
(Applause) —
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(掌声)—
08:45
this experiment finally nails the case
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这个实验最终证实
08:48
that this region of the brain is not only
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大脑这块区域
08:49
selectively responsive to faces
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不仅仅有选择性地对脸庞起反应,
08:52
but causally involved in face perception.
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还因此牵涉到脸的感知。
08:55
So I went through all of these details
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我快速过了一遍有关
08:57
about the face region to show you what it takes
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面部识别区域的细节来向你们展示
08:59
to really establish that a part of the brain
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是什么真正证实大脑的一部分
09:02
is selectively involved in a specific mental process.
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有选择地参与了特别的心理过程。
09:05
Next, I'll go through much more quickly
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接下来我会讲得更快一些。
09:07
some of the other specialized regions of the brain
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我会讲我们和其他人发现的
09:10
that we and others have found.
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其他有专门功能的大脑区域。
09:12
So to do this, I've spent a lot of time
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过去的一个月里,为了做这件事
09:14
in the scanner over the last month
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我已经在扫描仪里呆了很长时间,
09:16
so I can show you these things in my brain.
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来给你们看看我大脑里的这些东西。
09:18
So let's get started. Here's my right hemisphere.
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我们开始吧。这是我的右半脑。
09:21
So we're oriented like that. You're looking at my head this way.
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我们的方向是这样的。你们在从这个方向看我的大脑。
09:24
Imagine taking the skull off
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想象一下把头骨拿走,
09:25
and looking at the surface of the brain like that.
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像那样看着大脑的皮层。
09:27
Okay, now as you can see,
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那么,现在如你所见,
09:29
the surface of the brain is all folded up.
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大脑的皮层都是有褶皱的。
09:30
So that's not good. Stuff could be hidden in there.
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这可不太好,可能有东西会藏在里面。
09:32
We want to see the whole thing,
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我们想看看到完整的图像。
09:34
so let's inflate it so we can see the whole thing.
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那我们就展开它来看到完整的东西吧。
09:37
Next, let's find that face area I've been talking about
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接下来,我们来找一找一直都在说的那个
09:40
that responds to images like these.
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对像这些图像有反应的区域吧。
09:42
To see that, let's turn the brain around
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为了能看见它,我们把大脑转一圈,
09:43
and look on the inside surface on the bottom,
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从底部看大脑的内部表层,
09:45
and there it is, that's my face area.
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就是这了,这就是我的脸庞识别区域。
09:48
Just to the right of that is another region
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在它的右边是另一个
09:50
that is shown in purple
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标示成紫色的区域。
09:52
that responds when you process color information,
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当你在处理颜色信息时它会有反应。
09:55
and near those regions are other regions
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在这些区域的附近还有其他
09:58
that are involved in perceiving places,
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参与感知地点的区域。
10:00
like right now, I'm seeing this layout of space around me
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就像现在,我正在看着我周围的布局,
10:03
and these regions in green right there
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在那这些绿色的区域
10:05
are really active.
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非常的活跃。
10:06
There's another one out on the outside surface again
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还有一个区域在外部的大脑皮层,
10:08
where there's a couple more face regions as well.
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这儿也还有几个脸庞识别区域。
10:11
Also in this vicinity
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在这附近
10:14
is a region that's selectively involved
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有一个区域,专门参与
10:15
in processing visual motion,
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处理可视的物体移动
10:17
like these moving dots here,
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像这些移动的小点。
10:19
and that's in yellow at the bottom of the brain,
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就是这个在大脑底部的黄色部分。
10:21
and near that is a region that responds
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在那附近有一个区域,
10:25
when you look at images of bodies and body parts
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它在你看着身体或身体的部分时会有反应
10:27
like these, and that region is shown in lime green
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就是这些在大脑底部
10:30
at the bottom of the brain.
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标注成酸橙绿色的区域。
10:32
Now all these regions I've shown you so far
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目前为止我给你们展示的区域
10:35
are involved in specific aspects of visual perception.
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都参与了特定视觉感知的处理。
10:39
Do we also have specialized brain regions
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那么我们是否有大脑区域,
10:41
for other senses, like hearing?
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专门处理其他感官,比如听感呢?
10:44
Yes, we do. So if we turn the brain around a little bit,
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是的,我们有。如果我们稍微转转大脑。
10:47
here's a region in dark blue
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这有一个深蓝色区域。
10:50
that we reported just a couple of months ago,
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我们几个月前才报告了它的存在。
10:52
and this region responds strongly
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当你听到像这样的有音高的声音时,
10:54
when you hear sounds with pitch, like these.
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这个区域会强烈反应。
10:57
(Sirens)
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(警报)
10:59
(Cello music)
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(大提琴声)
11:01
(Doorbell)
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(门铃)
11:03
In contrast, that same region does not respond strongly
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相比之下,当你听到一些
11:07
when you hear perfectly familiar sounds
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像这些没有音高的熟悉的声音时,
11:08
that don't have a clear pitch, like these.
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这个区域反应不会那么强烈。
11:11
(Chomping)
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(咀嚼声)
11:13
(Drum roll)
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(鼓声)
11:15
(Toilet flushing)
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(马桶水声)
11:18
Okay. Next to the pitch region
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好的。在这个区域旁边
11:21
is another set of regions that are selectively responsive
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是另一堆专门对
11:23
when you hear the sounds of speech.
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说话声起反应的区域。
11:26
Okay, now let's look at these same regions.
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现在我们来看一看这些一样的区域。
11:28
In my left hemisphere, there's a similar arrangement —
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在我的左半脑,有相似的排列——
11:30
not identical, but similar —
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不是完全一样,但是很相似——
11:32
and most of the same regions are in here,
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大多数区域,尽管有时大小不同,
11:34
albeit sometimes different in size.
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2002
都排列在这里。
11:36
Now, everything I've shown you so far
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目前为止我给你们展示的东西
11:38
are regions that are involved in different aspects of perception,
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都是参与了不同感官,视觉和听觉,
11:41
vision and hearing.
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处理的区域。
11:43
Do we also have specialized brain regions
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那我们还有没有专门处理
11:44
for really fancy, complicated mental processes?
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很复杂的心理活动的区域呢?
11:48
Yes, we do.
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是的,我们有。
11:49
So here in pink are my language regions.
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这个粉色区域是我的语言区。
11:53
So it's been known for a very long time
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很早,人们就知道
11:54
that that general vicinity of the brain
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大脑中的这一片区域
11:56
is involved in processing language,
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参与了语言的处理,
11:58
but we showed very recently
299
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1732
但是我们最近才证实
12:00
that these pink regions
300
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这些粉色区域
12:02
respond extremely selectively.
301
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2205
极有选择性地起反应。
12:04
They respond when you understand the meaning of a sentence,
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它们在你理解一句话的意思时起反应,
12:07
but not when you do other complex mental things,
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却不在你做其他复杂心理活动起反应,
12:10
like mental arithmetic
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比如说心算,
12:12
or holding information in memory
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2396
或者试着记住一条信息,
12:14
or appreciating the complex structure
306
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2655
或者在欣赏一段音乐的
12:17
in a piece of music.
307
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2284
复杂结构。
12:21
The most amazing region that's been found yet
308
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2889
迄今为止发现的最神奇的区域
12:24
is this one right here in turquoise.
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3307
是这一片青绿色的部分。
12:27
This region responds
310
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2190
这片区域在你思考别人在思考什么的时候
12:30
when you think about what another person is thinking.
311
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4268
会有反应。
12:34
So that may seem crazy,
312
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这可能看起来很疯狂,
12:35
but actually, we humans do this all the time.
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但事实上,我们人类一直都在做这样的事。
12:39
You're doing this when you realize
314
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2193
当你意识到
12:42
that your partner is going to be worried
315
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1631
如果你不打电话回家
12:43
if you don't call home to say you're running late.
316
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2507
说你会跑步跑很晚,你的同伴会担心时
你的大脑在这样做。
12:46
I'm doing this with that region of my brain right now
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我现在就在用这块区域这样做。
12:49
when I realize that you guys
318
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2281
我在想你们在座各位
12:51
are probably now wondering about
319
771911
1598
可能会琢磨
12:53
all that gray, uncharted territory in the brain,
320
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2547
剩下的那块灰色的没标识的区域
12:56
and what's up with that?
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到底是起什么作用的?
12:58
Well, I'm wondering about that too,
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我也在琢磨这个问题。
12:59
and we're running a bunch of experiments in my lab right now
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2395
我们现在在实验室里做大量的实验
13:02
to try to find a number of other
324
782100
2013
来试着寻找其他
13:04
possible specializations in the brain
325
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2032
大脑可能存在的有特殊功能的
13:06
for other very specific mental functions.
326
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3368
高度专门化区域。
13:09
But importantly, I don't think we have
327
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2621
但是很重要的一点是,我不认为我们的大脑
13:12
specializations in the brain
328
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1564
对每一个重要的功能
13:13
for every important mental function,
329
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2746
甚至是关乎生存的功能
13:16
even mental functions that may be critical for survival.
330
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3409
都有专门处理的区域。
13:19
In fact, a few years ago,
331
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2102
事实上,几年前,
13:21
there was a scientist in my lab
332
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1117
有一位在我实验室的科学家,
13:23
who became quite convinced
333
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1409
非常确信地说
13:24
that he'd found a brain region
334
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1749
他发现了一块大脑区域
13:26
for detecting food,
335
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1912
专门用来识别食物。
13:28
and it responded really strongly in the scanner
336
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1918
在扫描仪里当人们看见这些图像时
13:30
when people looked at images like this.
337
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2728
这块区域会强烈反应。
13:32
And further, he found a similar response
338
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2912
此外,他还在12个对象的10个中的大脑中
13:35
in more or less the same location
339
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1939
几乎同样的区域
13:37
in 10 out of 12 subjects.
340
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2001
发现了相同的反应。
13:39
So he was pretty stoked,
341
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2294
他兴奋得不得了
13:41
and he was running around the lab
342
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1260
在实验室里跑跑跳跳
13:43
telling everyone that he was going to go on "Oprah"
343
823194
2002
告诉每一个人他就要带着他的研究成果
13:45
with his big discovery.
344
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2018
上奥普拉的脱口秀了。
13:47
But then he devised the critical test:
345
827214
3022
但接下来他做了一个修正实验:
13:50
He showed subjects images of food like this
346
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3183
他给实验对象展示了像这样的食物图片,
13:53
and compared them to images with very similar
347
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2741
并用了一些在形状和颜色上相似
13:56
color and shape, but that weren't food, like these.
348
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3810
但不是食物的图片做对比。
13:59
And his region responded the same
349
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2131
结果是那片区域对于两套图片的
14:02
to both sets of images.
350
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1949
反应强度是一样的。
14:04
So it wasn't a food area,
351
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1327
那么那就不是一块识别食物的区域了
14:05
it was just a region that liked colors and shapes.
352
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2771
只是一块会对颜色和形状产生反应的区域。
14:08
So much for "Oprah."
353
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2561
不过这也够拿上奥普拉脱口秀的台面了。
14:12
But then the question, of course, is,
354
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2225
但接下来的问题就是
14:14
how do we process all this other stuff
355
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2126
我们怎样用非专门化的大脑区域
14:16
that we don't have specialized brain regions for?
356
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2970
来处理其他的信息呢?
14:19
Well, I think the answer is that in addition
357
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1811
我认为答案就是
14:21
to these highly specialized components that I've been describing,
358
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3554
在我刚才说到的那些高度专门化部分以外
14:25
we also have a lot of very general- purpose machinery in our heads
359
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3679
我们大脑里还有很多非专业化的机件
14:28
that enables us to tackle
360
868848
1494
他们让我们能够处理
14:30
whatever problem comes along.
361
870342
2106
任何出现的困难。
14:32
In fact, we've shown recently that
362
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2055
事实上,我们最近证实了
14:34
these regions here in white
363
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2068
这些白色的区域
14:36
respond whenever you do any difficult mental task
364
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3411
会在你做任何困难的大脑工作时起反应。
14:39
at all —
365
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1101
在我们测试的七个中
14:41
well, of the seven that we've tested.
366
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3571
都是这样的结果。
14:44
So each of the brain regions that I've described
367
884654
2169
所以今天我给你们描述的
14:46
to you today
368
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1306
每一个大脑区域,
14:48
is present in approximately the same location
369
888129
2767
在正常的实验对象的大脑上
14:50
in every normal subject.
370
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1742
都在大概相同的位置。
14:52
I could take any of you,
371
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1623
我能挑你们其中的任意一个人,
14:54
pop you in the scanner,
372
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1226
把你塞进扫描仪,
14:55
and find each of those regions in your brain,
373
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2285
然后发现你大脑的那些区域
14:57
and it would look a lot like my brain,
374
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1905
和我大脑的区域非常相似。
14:59
although the regions would be slightly different
375
899677
2070
尽管可能这两者间
15:01
in their exact location and in their size.
376
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会在准确的位置和大小上有所不同。
15:05
What's important to me about this work
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对我而言这项工作最重要的
15:07
is not the particular locations of these brain regions,
378
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2969
不是那些大脑区域的准确位置,
15:10
but the simple fact that we have
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2587
而是我们得出的结论:
15:13
selective, specific components of mind and brain
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2568
我们的大脑和思想从一开始就由
15:15
in the first place.
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1648
选择性的和精细的各部分组成。
15:17
I mean, it could have been otherwise.
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2011
我的意思是,我们的大脑大可不必成为这样。
15:19
The brain could have been a single,
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2441
大脑可以是一个独立的,
15:21
general-purpose processor,
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1495
功能宽泛的处理器,
15:23
more like a kitchen knife
385
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1472
看起来更像一把菜刀
15:24
than a Swiss Army knife.
386
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1683
而不是瑞士军刀。
15:26
Instead, what brain imaging has delivered
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3111
但是,大脑成像呈现给我们的
15:29
is this rich and interesting picture of the human mind.
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3846
是人类思想的丰富的和有趣的图景。
15:33
So we have this picture of very general-purpose
389
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2463
这样这图片展示了大脑中
15:35
machinery in our heads
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1070
既有功能宽泛的机件,
15:37
in addition to this surprising array
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2357
也有令人惊讶的数量的
15:39
of very specialized components.
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3435
高度专门化的组分。
15:43
It's early days in this enterprise.
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2153
我们仍在这项研究的初期,
15:45
We've painted only the first brushstrokes
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2776
我们只在人类思想的神经学解释上
15:48
in our neural portrait of the human mind.
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2927
迈出了第一步。
15:51
The most fundamental questions remain unanswered.
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3082
最基本的问题仍然没有解答。
15:54
So for example, what does each of these regions do exactly?
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3800
比如说,每个这些区域究竟是做什么的?
15:58
Why do we need three face areas
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2142
为什么我们需要三个脸部区域
16:00
and three place areas,
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1465
和三个地点区域?
16:02
and what's the division of labor between them?
400
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2868
它们之间的分工是怎么样的?
16:04
Second, how are all these things
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2693
第二,这些东西
16:07
connected in the brain?
402
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1712
和大脑又是怎样联系起来的?
16:09
With diffusion imaging,
403
969330
1587
16:10
you can trace bundles of neurons
404
970917
2179
借助弥散成像,
你能够追踪许多连接到
16:13
that connect to different parts of the brain,
405
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2575
大脑各个部分的神经元。
16:15
and with this method shown here,
406
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1631
通过这里展示的方法,
16:17
you can trace the connections of individual neurons in the brain,
407
977302
3697
你就能找到单个神经元和大脑的联系。
16:20
potentially someday giving us a wiring diagram
408
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2718
这样也许有一天就能给我们
16:23
of the entire human brain.
409
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2066
一幅大脑的线路状图象。
16:25
Third, how does all of this
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2047
第三,这些非常系统的结构
16:27
very systematic structure get built,
411
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3149
是怎样在幼年的成长
16:30
both over development in childhood
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2956
和在物种的进化中
16:33
and over the evolution of our species?
413
993935
2812
被建立起来的呢?
16:36
To address questions like that,
414
996747
1900
为了解答这样的问题,
16:38
scientists are now scanning
415
998647
1783
科学家们现在在扫描
16:40
other species of animals,
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2157
其他种类的动物。
16:42
and they're also scanning human infants.
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5386
他们也在扫描人类婴孩。
16:48
Many people justify the high cost of neuroscience research
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3651
许多人为神经元科学研究的高成本辩护,
16:52
by pointing out that it may help us someday
419
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2754
他们指出这项研究也许某天会帮助我们
16:55
to treat brain disorders like Alzheimer's and autism.
420
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3457
治疗如阿兹海默症和自闭症这些神经紊乱。
16:58
That's a hugely important goal,
421
1018793
1947
17:00
and I'd be thrilled if any of my work contributed to it,
422
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3221
这是极其重要的目标,
如果我的工作能够给予帮助,我将非常激动。
17:03
but fixing things that are broken in the world
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2998
但是修理世上已经坏掉的东西
17:06
is not the only thing that's worth doing.
424
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2801
不是唯一值得去做的事。
17:09
The effort to understand the human mind and brain
425
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3228
为了了解人类心理和大脑而做出的努力
17:12
is worthwhile even if it never led to the treatment
426
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2818
即使无法用于治疗某种疾病
17:15
of a single disease.
427
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1677
也是有价值的。
17:17
What could be more thrilling
428
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2037
还有什么事
17:19
than to understand the fundamental mechanisms
429
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3141
能比了解人类体验的基础机制
17:22
that underlie human experience,
430
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2296
和本质上了解“我们是谁”
17:24
to understand, in essence, who we are?
431
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2926
更令人激动的呢?
17:27
This is, I think, the greatest scientific quest
432
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3449
我认为,这是有史以来
17:31
of all time.
433
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2713
最伟大的科学探寻
17:34
(Applause)
434
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5470
(掌声)
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