A life-saving device that detects silent heart attacks | Akash Manoj

Prevodilac: Dragana Savanovic Lektor: Ivana Krivokuća

When I was 13,

I lost my grandfather to a silent heart attack.

What happened to be more shocking was that at 75,

Kada sam imao 13 godina,

izgubio sam dedu zbog tihog infarkta.

grandpa was really normal, healthy and energetic,

Još šokantnije je što je deka, sa svojih 75 godina,

but he was diabetic.

bio vrlo normalan, zdrav i energičan,

Learning all of this was so painful

that I decided to go out on a war against this deadly killer

ali je bio dijabetičar.

Ovo saznanje je bilo tako bolno

and see what could be done.

da sam odlučio da se borim protiv ovog ubice

It was shocking to discover the results of recent studies

that have shown an estimate of nearly eight million people

i da vidim šta se može uraditi.

Bilo je šokantno otkriti rezultate skorašnjeg istraživanja

who die from heart attacks every year.

koje procenjuje da blizu osam miliona ljudi

Heart attacks occur for many reasons,

but most often, they occur when arteries get clogged,

svake godine umre od infarkta.

Infarkti se dešavaju iz mnogo razloga,

blood flow is cut off

ali najčešće, kada se arterije začepe,

and oxygen-starved cells in the heart muscles start to die.

You may know the common symptoms of a heart attack:

dotok krvi se prekine

i ćelije srčanih mišića bez kiseonika počinju da odumiru.

chest pain, arm pain, shortness of breath, fatigue, et cetera ...

Možda znate koji su uobičajeni simptomi infarkta:

bol u grudima i ruci, nedostatak daha, umor itd...

but there is a type of heart attack that is quite common,

just as deadly,

but harder to detect because the symptoms are silent.

Ali postoji vrsta infarkta koja je česta

i jednako smrtonosna,

People having silent heart attacks just don't realize what's happening,

ali teža za uočavanje jer su simptomi tihi.

so they're not seeking medical attention,

Ljudi koji doživljavaju tihi infarkt prosto ne shvataju šta se dešava,

which means they're less likely to receive the treatment that they need

pa ne potraže medicinsku pomoć,

at the critical moment.

što znači da su manje šanse da dobiju potrebno lečenje

And even if they do get to the hospital by chance,

u kritičnom trenutku.

either before or after they are struck by a heart attack,

A čak i ako, nekim slučajem, stignu u bolnicu,

they might have to go through one or more of these time-consuming, expensive tests

pre ili nakon infarkta,

and treatments,

možda moraju da prođu kroz jedan ili više dugotrajnih, skupih testova

which are currently considered the gold standards

of heart-attack diagnosis.

The greater concern, however,

i terapija,

koji se trenutno smatraju najvišim standardima

is that these silent heart attacks account for nearly 45 percent

u dijagnostici infarkta.

of all heart attacks.

Još veći problem je, pak,

što ovi tihi infarkti čine blizu 45 posto

Patients with diabetes and similar disorders suffer from nerve damage

svih infarkata.

that prevents them from feeling the sort of pain

Pacijenti sa dijabetesom i sličnim oboljenjima

that usually signals to someone

imaju nervna oštećenja zbog kojih ne osećaju onu vrstu bola

that he or she may be having a heart attack.

koja uglavnom signalizira osobi

Which means they suffer the damage of a heart attack

da doživljava infarkt.

without even knowing or feeling anything.

Što znači da ti pacijenti dožive oštećenje srca

These already at-risk patients suffer from nerve damage,

a da ne znaju ili osećaju bilo šta.

and they do not get immediate medical care.

Ovi ionako ugroženi pacijenti dožive nervno oštećenje,

They do not know anything before an unlikely event is about to occur.

a ne dobiju hitnu medicinsku pomoć.

My grandfather was an at-risk patient, too.

Oni ništa ne znaju pre nego što se nemili događaj desi.

I probed this issue further --

Moj deda je, takođe, bio ugrožen pacijent.

read as much as I could to understand the heart,

met researchers and worked across labs in India.

Istraživao sam ovaj problem još -

čitao što sam više mogao da razumem srce,

And finally, after three long years of persistent research,

upoznao istraživače i radio u laboratorijama širom Indije.

what I have to share with the world today is a promising solution.

Napokon, nakon tri duge godine istrajnog istraživanja,

A noninvasive device that is inexpensive,

ono što danas imam da podelim sa svetom je rešenje koje obećava.

portable, wearable by at-risk patients at all times.

Neinvazivni uređaj koji nije skup,

koji je prenosiv, i ugroženi pacijenti mogu stalno da ga nose.

It greatly reduces the need for a blood test

and works 24/7, collecting and analyzing data at preset intervals.

Smanjuje potrebu za analizom krvi i radi danonoćno,

And all this data is collected for a single purpose:

skupljajući i analizirajući podatke u unapred podešenim intervalima.

detecting heart attacks as they occur.

A svi ti podaci se skupljaju iz jednog razloga:

This is a very promising solution that might help us in the future.

da otkriju infarkte kada se jave.

You may not know how intelligent your heart really is.

Ovo je rešenje koje mnogo obećava i koje bi ubuduće moglo da nam pomogne.

It tries to communicate to your body multiple times before failing,

Možda ne znate koliko je vaše srce inteligentno.

by indicating symptoms like chest pain.

Ono pokušava da komunicira sa vašim telom više puta pre nego što otkaže,

These symptoms are triggered when the heart loses out

ukazujući na simptome kao što je bol u grudima.

on oxygen-rich blood flow.

Ovi simptomi se aktiviraju kada srce izgubi

But remember I told you about the nerve damage.

protok krvi bogat kiseonikom.

It silences these symptoms before a silent heart attack,

Sećate se da sam vam pričao o nervnom oštećenju.

which makes it even deadlier.

Ono utišava ove simptome pre tihog infarkta,

And you may not even know the common symptoms.

što ga čini još smrtonosnijim.

Meanwhile, the heart also sends out certain biomarkers --

A možda i ne znate koji su uobičajeni simptomi.

cardiac biomarkers or proteins that are SOS messages --

U međuvremenu, srce takođe šalje određene biomarkere -

in the form of SOS messages --

srčane biomarkere ili proteine koji su pozivi u pomoć -

into your bloodstream,

indicating that the heart is at risk.

kao poziv u pomoć -

As it gets riskier and riskier,

u vaš krvotok,

the concentrations of these cardiac biomarker proteins

ukazujući da je srce ugroženo.

Kako situacija postaje rizičnija,

keep increasing abysmally.

My device solely relies on this data.

koncentracije ovih srčanih proteinskih biomarkera

nastave katastrofalno da se povećavaju.

The key is that these cardiac biomarkers are found

Moj uređaj se oslanja isključivo na ove podatke.

in one of the earliest stages of a heart attack,

when someone is almost sure to survive

Cilj je da se ovi biomarkeri otkriju

u najranijoj fazi infarkta

if he or she gets prompt care.

kada su najveće šanse za preživljavanje

And my device is solely based on that basis.

ako se dobije brza nega.

And here's how my device works.

A moj uređaj se isključivo zasniva na tome.

A silicon patch is worn around your wrist or placed near your chest.

I evo kako on funkcioniše.

Without having to prick your skin for a biomarker blood test,

Silikonski zavoj se nosi oko ručnog zgloba ili se stavlja blizu grudi.

this patch can spot, isolate and track a heart-attack specific biomarker

Bez potrebe da bodete kožu radi krvnog testa na biomarker,

ovaj zavoj može da uoči, izoluje i prati biomarker specifičan za infarkt

called H-FABP,

and alerts you if and when it reaches a critical level in your bloodstream --

zvani H-FABP,

i upozorava vas ako i kada dostigne kritični nivo u vašem krvotoku -

a process that's much simpler, easier and cheaper than conventional methods

što je mnogo jednostavnije, lakše i jeftinije

of heart-attack diagnosis.

By checking on biomarker concentration data,

nego tradicionalne metode za dijagnozu infarkta.

a system like this, with advanced research in the future,

Proveravajući podatke o koncentraciji biomarkera,

could significantly reduce the need for an at-risk patient to go to a doctor

ovakav sistem,

uz napredno istraživanje u budućnosti,

for a biomarker blood test,

može značajno smanjiti potrebu ugroženog pacijenta da ode lekaru

because the device could be worn at all times,

sensing biomarker elevations in real time.

zbog analize krvi na biomarkere,

jer se uređaj može uvek nositi

Thus, if the device senses the biomarker levels going beyond the critical point,

i detektovati povišenje biomarkera u realnom vremenu.

the at-risk patient could be warned of an impending cardiac arrest

Prema tome, ako uređaj primeti da je nivo biomarkera iznad kritične tačke,

and that he or she needs immediate medical attention.

ugroženi pacijent može biti upozoren na predstojeći srčani zastoj

Although the device may not be able to provide the patient

i da mu treba hitna medicinska pomoć.

with the complete analysis of the cardiac injury,

Iako uređaj možda ne može da pruži pacijentu

it might be of immense help

in actually indicating that the patient is in danger,

kompletnu analizu povrede srca,

so that the patient can be alarmed

može biti od velike pomoći

and know that immediate care is crucial.

u nagoveštavanju da je pacijent u opasnosti,

Every at-risk patient will now receive more time to survive

tako da pacijent može biti upozoren

da mu je hitna pomoć neophodna.

and reach out for medical help.

Svaki ugroženi pacijent će sada imati više vremena da preživi

Consequently, they don't have to go

for expensive and invasive medical treatments

i da potraži medicinsku pomoć.

that would otherwise be necessary after a heart attack.

Zbog toga pacijentima nisu neophodni

skupi i invazivni medicinski tretmani

When I got my device tested on at-risk patients under observation,

koji bi inače bili neophodni nakon infarkta.

results from the clinical validation tests

Kada sam testirao svoj uređaj na ugroženim pacijentima pod nadzorom,

certified close to a 96 percent accuracy and sensitivity.

rezultati kliničkog testa validnosti

I intend to make my device available to people in two variants:

su potvrdili blizu 96 posto tačnosti i osetljivosti.

one which gives digital analysis of the biomarker levels

Nameravam da svoj uređaj ljudima učinim dostupnim u dve varijante:

and a simpler version for the people in rural areas

jednoj, koja daje digitalnu analizu nivoa biomarkera,

which simply vibrates when the biomarker levels go beyond the critical point.

i jednostavniju verziju za ljude u ruralnim oblastima

When we look at our progress in cardiac health care today,

koja vibrira kada se nivoi biomarkera popnu iznad kritične tačke.

it is more of sick care than preventative self-care and technology.

Kada pogledamo naš napredak u lečenju kardioloških problema,

We literally wait for the heart attack to occur

to je više nega bolesnih nego preventivna briga i tehnologija.

and put our vast majority of resources into post-care treatment.

Mi bukvalno čekamo da se infarkt dogodi

But by then, irreversible damage will already be done.

i ulažemo ogromne resurse u negu nakon infarkta.

I firmly believe it's time for us to rethink medicine.

Do tada, nepovratna šteta će već biti učinjena.

We must establish proactive health-care technologies.

Čvrsto verujem da je vreme da preispitamo medicinu.

A change must be brought out not 10 years from now,

Moramo uspostaviti proaktivnu tehnologiju zdravstvene nege.

not five years from now,

but today.

And so, hopefully, one day,

Moramo napraviti promenu ne za deset godina,

with the help of these devices,

ne za pet godina,

someone else won't lose his or her grandfather just like I did.

nego danas.

I tako, nadam se, jednog dana,

uz pomoć ovih uređaja,

Thank you so much.

neko neće izgubiti svog dedu kao što sam ja.

(Applause)

Thank you.

(Applause)

Hvala vam mnogo.

Thank you.

(Aplauz)

Hvala vam.

(Aplauz)

Hvala vam.