Noel Bairey Merz: The single biggest health threat women face

64,640 views ・ 2012-03-21

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Prevoditelj: Senzos Osijek Recezent: Tilen Pigac - EFZG
00:15
One out of two of you women
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Jedna od dvije među vama ženama
00:18
will be impacted by cardiovascular disease
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bit će pogođena kardiovaskularnom bolešću
00:20
in your lifetime.
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tijekom svog života.
00:23
So this is the leading killer of women.
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Ta je bolest vodeći ubojica među ženama.
00:27
It's a closely held secret
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To je dobro čuvana tajna
00:29
for reasons I don't know.
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iz razloga koji meni nisu poznati.
00:32
In addition to making this personal --
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Osim što ćemo to shvatiti osobno --
00:35
so we're going to talk about your relationship with your heart
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govorit ćemo o vašem odnosu s vašim srcem
00:37
and all women's relationship with their heart --
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i odnosu svih žena prema srcu --
00:40
we're going to wax into the politics.
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zadrijet ćemo u politiku.
00:42
Because the personal, as you know, is political.
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Ono što vas se osobno tiče, kao što znate, ujedno je politika.
00:45
And not enough is being done about this.
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A nije dovoljno napravljeno oko toga.
00:48
And as we have watched women
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I kao što smo gledali kako se žene
00:50
conquer breast cancer
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bore protiv tumora dojke
00:52
through the breast cancer campaign,
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u kampanjama protiv tumora dojke,
00:54
this is what we need to do now with heart.
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to je ono što treba učiniti sada sa srcem.
00:57
Since 1984,
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Od 1984.
00:59
more women die in the U.S. than men.
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u SAD-u umire više žena nego muškaraca.
01:03
So where we used to think of heart disease
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Obično se mislilo kako je srčana bolest
01:06
as being a man's problem primarily --
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prvenstveno muški problem --
01:09
which that was never true,
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što nikad nije bilo istina,
01:11
but that was kind of how everybody thought in the 1950s and '60s,
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ali tako su svi mislili u 50-ima i 60-ima
01:14
and it was in all the textbooks.
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i tako je pisalo u svim udžbenicima.
01:16
It's certainly what I learned when I was training.
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To je svakako ono što sam ja naučila kao student.
01:19
If we were to remain sexist, and that was not right,
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Kad bismo ostali seksisti, što nije bilo ispravno,
01:22
but if we were going to go forward and be sexist,
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ali ako nastavimo biti seksisti,
01:25
it's actually a woman's disease.
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to je ustvari ženska bolest.
01:27
So it's a woman's disease now.
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To je sada ženska bolest.
01:29
And one of the things that you see
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A jedna od stvari koju možete vidjeti
01:31
is that male line,
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na muškoj liniji,
01:33
the mortality is going down, down, down, down, down.
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smrtnost pada sve niže, niže, niže, niže i niže.
01:35
And you see the female line since 1984,
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I vidite žensku liniju od 1984.
01:38
the gap is widening.
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raspon se povećava.
01:40
More and more women, two, three, four times more women,
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Sve više i više žena, dva, tri, četiri puta više žena
01:43
dying of heart disease than men.
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umire od srčane bolesti nego muškaraca.
01:46
And that's too short of a time period
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A to je premali vremenski period
01:48
for all the different risk factors that we know
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da bi se promijenili svi mogući rizični faktori
01:50
to change.
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koje poznajemo.
01:52
So what this really suggested to us
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To je nama na nacionalnoj razini
01:54
at the national level
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ustvari sugeriralo
01:56
was that diagnostic and therapeutic strategies,
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kako dijagnostičke i terapeutske strategije
02:00
which had been developed in men, by men, for men
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koje su bile razvijene u muškaraca, od strane muškaraca, za muškarce
02:03
for the last 50 years --
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u zadnjih 50 godina --
02:05
and they work pretty well in men, don't they? --
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i one su prilično učinkovite kod muškaraca, zar ne? --
02:08
weren't working so well for women.
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nisu učinkovite kod žena.
02:11
So that was a big wake-up call
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Tako je to bio veliki poziv na buđenje
02:13
in the 1980's.
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u 1980-ima.
02:15
Heart disease kills more women
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Bolest srca ubija više žena
02:18
at all ages
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u svim dobnim skupinama
02:20
than breast cancer.
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nego tumor dojke.
02:22
And the breast cancer campaign --
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A kampanja protiv tumora dojke --
02:24
again, this is not a competition.
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ponavljam, ovo nije natjecanje.
02:26
We're trying to be as good as the breast cancer campaign.
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Pokušavamo biti jednako dobri kao kampanja protiv tumora dojke
02:29
We need to be as good as the breast cancer campaign
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kako bismo se suočili
02:32
to address this crisis.
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s ovom krizom.
02:34
Now sometimes when people see this,
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Ponekad kad ljudi vide ovo,
02:36
I hear this gasp.
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čujem te uzdisaje.
02:38
We can all think of someone,
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Svatko se od nas može sjetiti,
02:40
often a young woman,
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često mlade žene,
02:42
who has been impacted by breast cancer.
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koja je bila pogođena tumorom dojke.
02:45
We often can't think of a young woman
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Često se ne možemo sjetiti mlade žene
02:47
who has heart disease.
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koja je bila pogođena srčanom bolešću.
02:49
I'm going to tell you why.
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Reći ću vam zašto.
02:51
Heart disease kills people,
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Srčana bolest obično
02:53
often very quickly.
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ubija ljude brzo.
02:55
So the first time heart disease strikes in women and men,
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Tako pri prvom udaru srčane bolesti u žena ili muškaraca,
02:58
half of the time it's sudden cardiac death --
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kod polovice nastupa iznenadna srčana smrt --
03:01
no opportunity to say good-bye,
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nemate priliku reći zbogom,
03:03
no opportunity to take her to the chemotherapy,
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nemate priliku odvesti je na kemoterapiju,
03:05
no opportunity to help her pick out a wig.
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nema prilike pomoći joj da spakuje svoje stvari.
03:08
Breast cancer,
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Smrtnost od tumora dojke
03:10
mortality is down to four percent.
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pala je za 4%.
03:13
And that is the 40 years
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A to je nakon 40 godina
03:15
that women have advocated.
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ženskog zalaganja.
03:19
Betty Ford, Nancy Reagan stood up
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Betty Ford, Nancy Reagan digle su se
03:22
and said, "I'm a breast cancer survivor,"
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i rekle „Ja sam preživjela tumor dojke“
03:24
and it was okay to talk about it.
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i bilo je u redu govoriti o tome.
03:26
And then physicians have gone to bat.
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A onda su kliničari bili na udaru.
03:28
We've done the research.
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Napravili smo istraživanja.
03:30
We have effective therapies now.
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I danas imamo učinkovitu terapiju.
03:32
Women are living longer than ever.
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Žene žive dulje nego ikada.
03:34
That has to happen in heart disease, and it's time.
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To se mora dogoditi sa srčanom bolešću, vrijeme je.
03:37
It's not happening, and it's time.
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Ne događa se, a vrijeme je.
03:42
We owe an incredible debt of gratitude
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Dugujemo veliku zahvalnost
03:44
to these two women.
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tim dvjema ženama.
03:46
As Barbara depicted
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Kao što je Barbara prikazala
03:48
in one of her amazing movies, "Yentl,"
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u jednom od svojih fantastičnih filmova, „Yentl“,
03:52
she portrayed a young woman
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ona portretira mladu ženu
03:54
who wanted an education.
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koja se želi obrazovati.
03:57
And she wanted to study the Talmud.
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Ona je željela studirati Talmud.
03:59
And so how did she get educated then?
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I kako se onda obrazovala?
04:01
She had to impersonate a man.
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Morala je utjeloviti muškarca.
04:03
She had to look like a man.
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Morala je izgledati kao muškarac.
04:05
She had to make other people believe that she looked like a man
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Ona je morala uvjeriti druge ljude da izgleda kao muškarac
04:08
and she could have the same rights
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i onda je mogla imati ista prava
04:10
that the men had.
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kakva su imali muškarci.
04:12
Bernadine Healy, Dr. Healy,
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Bernadine Healy, Dr. Healy,
04:15
was a cardiologist.
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bila je kardiolog.
04:17
And right around that time, in the 1980's,
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I upravo u to vrijeme, u 1980-ima,
04:20
that we saw women and heart disease deaths
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kada smo vidjeli kako žene i smrtnost od srčane bolesti
04:22
going up, up, up, up, up,
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rastu sve više, i više,i više, i više, i više,
04:24
she wrote an editorial
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napisala je uvodni članak
04:26
in the New England Journal of Medicine
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za New England Journal of Medicine (*renomirani medicinski časopis)
04:28
and said, the Yentl syndrome.
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i rekla –Yentl sindrom.
04:31
Women are dying of heart disease,
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Žene umiru od srčane bolesti,
04:33
two, three, four times more than men.
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dva, tri, četiri puta više nego muškarci.
04:36
Mortality is not going down, it's going up.
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Smrtnost se ne spušta, ona se podiže.
04:39
And she questioned,
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I onda je pitala,
04:41
she hypothesized,
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hipotetizirala je:
04:43
is this a Yentl syndrome?
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„Je li to Yentl sindrom?“
04:45
And here's what the story is.
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A evo u čemu je stvar.
04:47
Is it because women don't look like men,
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Tako je zato što žene ne izgledaju kao muškarci,
04:50
they don't look like that male-pattern heart disease
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one ne sliče tom muškom obrascu
04:53
that we've spent the last 50 years understanding
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na čije smo razumijevanje potrošili zadnjih 50 godina
04:56
and getting really good diagnostics
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i na dobivanje stvarno dobre dijagnostike
04:58
and really good therapeutics,
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i stvarno dobre terapije
05:00
and therefore, they're not recognized for their heart disease.
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i zato njihove srčane bolesti nisu prepoznate.
05:02
And they're just passed.
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I one su samo propuštene.
05:04
They don't get treated, they don't get detected,
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Ne dobivaju tretman, ne budu prepoznate,
05:07
they don't get the benefit of all the modern medicines.
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ne dobivaju prednosti sve te moderne medicine.
05:10
Doctor Healy then subsequently became
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Doktorica Healy zatim je postala
05:12
the first female director
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prva žena direktorica
05:14
of our National Institutes of Health.
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Nacionalnog instituta za zdravlje (NIH).
05:16
And this is the biggest biomedical enterprise research
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A to je najveći biomedicinski znanstveni poduhvat
05:19
in the world.
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na svijetu.
05:21
And it funds a lot of my research.
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Taj fond financira veliki dio mog istraživanja.
05:23
It funds research all over the place.
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On financira istraživanja posvuda.
05:25
It was a very big deal
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Bila je velika stvar
05:27
for her to become director.
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za nju postati direktoricom.
05:29
And she started,
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I ona je počela,
05:31
in the face of a lot of controversy,
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uz mnogo kontroverze,
05:33
the Women's Health Initiative.
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Inicijativu za žensko zdravlje.
05:35
And every woman in the room here
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A svaka je žena u ovoj prostoriji
05:37
has benefited from that Women's Health Initiative.
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imala koristi od Inicijative za žensko zdravlje.
05:39
It told us about hormone replacement therapy.
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Ona nas je naučila hormonskoj nadomjesnoj terapiji.
05:42
It's informed us about osteoporosis.
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Informirala nas o osteoporozi.
05:44
It informed us about breast cancer, colon cancer in women.
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Informirala nas o tumoru dojke, tumoru kolona kod žena.
05:47
So a tremendous fund of knowledge
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Ogroman fundus znanja,
05:50
despite, again,
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usprkos tome, još jednom,
05:52
that so many people told her not to do it,
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što joj je mnogo ljudi reklo da to ne čini,
05:54
it was too expensive.
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to je bilo preskupo.
05:56
And the under-reading was women aren't worth it.
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A smisao je bio kako žene nisu toga vrijedne.
05:59
She was like, "Nope. Sorry. Women are worth it."
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No, ona je rekla: „A ne. Žao mi je. Žene to zaslužuju.“
06:02
Well there was a little piece of that Women's Health Initiative
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Dakle u tome je bio i mali djelić Inicijative za žensko zdravlje
06:05
that went to National Heart, Lung, and Blood Institute,
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koji je pripao Nacionalnom institutu za srce, pluća i krv,
06:07
which is the cardiology part of the NIH.
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koji je kardiološki dio NIH-a.
06:10
And we got to do the WISE study --
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I tako smo došli do WISE studije --
06:12
and the WISE stands for Women's Ischemia Syndrome Evaluation --
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a WISE znači Women's Ischemia Syndrome Evaluation (Evaluacija ženskog ishemijskog sindroma) --
06:16
and I have chaired this study for the last 15 years.
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a ja sam predsjedavala tom studijom zadnjih 15 godina.
06:18
It was a study to specifically ask,
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To je bila studija koja je specifično pitala
06:21
what's going on with women?
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što se događa sa ženama?
06:23
Why are more and more women dying
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Zašto sve više i više žena umire
06:25
of ischemic heart disease?
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od ishemijske bolesti srca?
06:27
So in the WISE, 15 years ago,
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U WISE-u smo, prije 15 godina,
06:30
we started out and said, "Well wow, there's a couple of key observations
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započeli i rekli : „No dakle, nekoliko je ključnih opažanja
06:33
and we should probably follow up on that."
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i vjerojatno bismo ih trebali slijediti“.
06:35
And our colleagues in Washington, D.C.
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Naš kolega iz Washingtona
06:38
had recently published
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nedavno je objavio
06:41
that when women have heart attacks and die,
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kako, kad žene umru od srčanog udara,
06:44
compared to men who have heart attacks and die --
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u usporedbi s muškarcima koji umru od srčanog udara --
06:47
and again, this is millions of people,
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i opet, to su milijuni ljudi,
06:49
happening every day --
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događa se svaki dan --
06:52
women, in their fatty plaque --
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žene, u svojim masnim plakovima --
06:54
and this is their coronary artery,
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a ovo je njihova koronarna arterija,
06:56
so the main blood supply going into the heart muscle --
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dakle glavna opskrba krvlju koja ide u srčani mišić --
06:58
women erode,
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kod žena erodira,
07:00
men explode.
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a u muškaraca eksplodira.
07:03
You're going to find some interesting analogies
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Pronaći ćete nekoliko zanimljivih analogija
07:05
in this physiology.
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u toj fiziologiji.
07:07
(Laughter)
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(Smijeh)
07:10
So I'll describe the male-pattern heart attack first.
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Dakle, kao prvo ću opisati muški obrazac srčanog udara.
07:13
Hollywood heart attack. Ughhhh.
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Hollywoodski srčani udar. Ahhhh.
07:15
Horrible chest pain.
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Užasna bol u prsima.
07:17
EKG goes pbbrrhh,
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EKG krene pbbrrhhh,
07:19
so the doctors can see this hugely abnormal EKG.
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tako da doktori mogu vidjeti taj enormno abnormalni EKG.
07:22
There's a big clot in the middle of the artery.
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U srednjoj je arteriji ogromni ugrušak.
07:24
And they go up to the cath lab
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Oni odlaze u kat- laboratorij
07:26
and boom, boom, boom get rid of the clot.
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i bum, bum, odstrane ugrušak.
07:28
That's a man heart attack.
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To je muški srčani udar.
07:30
Some women have those heart attacks,
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Neke žene imaju takve srčane udare,
07:32
but a whole bunch of women have this kind of heart attack,
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ali cijelo čudo žena ima takve srčane udare
07:34
where it erodes,
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u kojima dolazi do erozije,
07:36
doesn't completely fill with clot, symptoms are subtle,
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arterija nije sasvim začepljena ugruškom, simptomi su prigušeni,
07:39
EKG findings are different --
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EKG nalaz drugačiji --
07:41
female-pattern.
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ženski obrazac.
07:43
So what do you think happens to these gals?
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I što mislite što se dogodi s tim curama?
07:46
They're often not recognized, sent home.
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Često nisu prepoznate, pošalje ih se kući.
07:48
I'm not sure what it was. Might have been gas.
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Nisam sigurna što je to bilo. Možda su bili samo vjetrovi.
07:51
So we picked up on that
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Mi smo se zakačili za to
07:53
and we said, "You know, we now have the ability
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i rekli, „Znate, sada imamo sposobnost
07:56
to look inside human beings
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pogledati unutar ljudskog bića
07:59
with these special catheters called IVUS:
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s tim posebnim kateterima koji se zovu IVUS:
08:01
intravascular ultrasound."
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intravaskularni ultrazvuk“.
08:03
And we said, "We're going to hypothesize
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Pa smo rekli, „Pretpostavit ćemo
08:06
that the fatty plaque in women
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kako su masni plakovi u žena
08:09
is actually probably different,
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ustvari možda različiti,
08:11
and deposited differently, than men."
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drugačije istaloženi nego u muškaraca.“
08:13
And because of the common knowledge
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I zbog općeg znanja
08:17
of how women and men get fat.
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kako žene i muškarci postaju debeli.
08:19
When we watch people become obese,
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Kad smo promatrali ljude kako postaju pretili,
08:23
where do men get fat?
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gdje muškarci sakupljaju masti?
08:26
Right here, it's just a focal -- right there.
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Upravo ovdje, to je fokalno -- upravo tu.
08:30
Where do women get fat?
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Kako se žene debljaju?
08:33
All over.
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Posvuda.
08:35
Cellulite here, cellulite here.
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Celulit ovdje, celulit ovdje.
08:38
So we said, "Look, women look like they're pretty good
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Pa smo rekli, „Gledajte, čini se kako su žene prilično dobre
08:40
about putting kind of the garbage away,
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u stavljanju neke vrste smeća u stranu,
08:42
smoothly putting it away.
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glatkom uklanjanju.
08:44
Men just have to dump it in a single area."
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Muškarci to baš moraju staviti na jedno mjesto“.
08:47
So we said, "Let's look at these."
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Pa smo rekli,“Hajdemo to pogledati.“
08:49
And so the yellow is the fatty plaque,
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Ovo žuto je masni plak,
08:52
and panel A is a man.
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a snimak A je muškarac.
08:54
And you can see, it's lumpy bumpy.
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I vi možete vidjeti, to je nepravilno grudasto.
08:56
He's got a beer belly in his coronary arteries.
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On je dobio pivski stomačić u svojoj koronarnoj arteriji.
08:59
Panel B is the woman, very smooth.
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Snimak B je žena, vrlo glatko.
09:01
She's just laid it down nice and tidy.
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Ona je to posložila lijepo i uredno.
09:03
(Laughter)
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(Smijeh)
09:05
And if you did that angiogram,
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I ako napravite taj angiogram,
09:07
which is the red,
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koji je to crveno,
09:09
you can see the man's disease.
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vidite mušku bolest.
09:11
So 50 years
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Pedeset godina
09:13
of honing and crafting these angiograms,
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brušenja i rezbarenja tih angiograma,
09:15
we easily recognize
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lagano prepoznajemo
09:17
male-pattern disease.
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muški obrazac bolesti.
09:19
Kind of hard to see that female-pattern disease.
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Nekako je teško vidjeti ženski obrazac bolesti.
09:21
So that was a discovery.
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Dakle to je bilo otkriće.
09:23
Now what are the implications of that?
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I sada koje su posljedice toga?
09:26
Well once again, women get the angiogram
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Dakle još jednom, ženama naprave angiogram
09:28
and nobody can tell that they have a problem.
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i nitko ne može reći kako imaju problem.
09:31
So we are working now on a non-invasive --
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Sada radimo na neinvazivnom --
09:34
again, these are all invasive studies.
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ponavljam, ovo su sve invazivne studije.
09:36
Ideally you would love to do all this non-invasively.
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Idealno biste željeli sve ovo učiniti neinvazivno.
09:39
And again, 50 years
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I opet, 50 godina
09:41
of good non-invasive stress testing,
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dobrog neinvazivnog stresnog testiranja,
09:43
we're pretty good at recognizing male-pattern disease
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prilično smo dobri u prepoznavanju muškog obrasca bolesti
09:45
with stress tests.
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sa stresnim testiranjem.
09:47
So this is cardiac magnetic resonance imaging.
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Dakle ovo je magnetska rezonancija srca.
09:49
We're doing this at the Cedars-Sinai Heart Institute
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Ovo radimo na Cedars-Sinai Institutu za srce
09:52
in the Women's Heart Center.
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u Centru za žensko srce.
09:54
We selected this for the research.
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Ovo smo odabrali za istraživanje.
09:57
This is not in your community hospital,
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To nije vaša opća bolnica,
09:59
but we would hope to translate this.
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ali mi se nadamo da će tamo biti preneseno.
10:01
And we're about two and a half years
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I sada smo dvije i pol godine
10:03
into a five-year study.
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unutar petogodišnje studije.
10:05
This was the only modality
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Ovo je bio jedini način
10:07
that can see the inner lining of the heart.
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kojim se vidi unutarnja postava srca.
10:09
And if you look carefully, you can see
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I ako pažljivo pogledate, vidjet ćete
10:11
that there's a black blush right there.
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crno zatamnjenje upravo ovdje.
10:13
And that is microvascular obstruction.
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To je mikrovaskularna obstrukcija.
10:16
The syndrome, the female-pattern
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Sindrom, ženski obrazac
10:19
now is called microvascular coronary dysfunction, or obstruction.
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sada se zove mikrovaskularna koronarna disfunkcija ili obstrukcija.
10:23
The second reason we really liked MRI
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Drugi razlog radi kojega stvarno volimo MRI
10:26
is that there's no radiation.
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je taj što nema radijacije.
10:28
So unlike the CAT scans, X-rays, thalliums,
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Pa za razliku od CAT snimanja, X-zraka, thaliuma,
10:31
for women
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za žene
10:33
whose breast is in the way
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kojima su dojke prepreka
10:35
of looking at the heart,
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pregledu srca,
10:37
every time we order something that has even a small amount of radiation,
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svaki puta kada naručimo nekakav pregled koji ima i najmanje doze radijacije,
10:40
we say, "Do we really need that test?"
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kažemo „Trebamo li stvarno taj test?“
10:42
So we're very excited about M.R.
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Tako smo mi stvarno uzbuđeni oko MR-a.
10:44
You can't go and order it yet,
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To još ne možete naručiti,
10:46
but this is an area of active inquiry
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ali to je područje aktivnog istraživanja
10:48
where actually studying women
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gdje će ustvari istraživanje žena
10:50
is going to advance the field for women and men.
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unaprijediti polje i za žene i za muškarce.
10:54
What are the downstream consequences
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I koje su onda nizvodne posljedice
10:57
then, when female-pattern heart disease
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ako se ženski obrazac srčane bolesti
11:00
is not recognized?
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ne prepozna?
11:02
This is a figure
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Ovo je prikaz
11:04
from an editorial that I published
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iz uvodnika koji sam objavila
11:06
in the European Heart Journal this last summer.
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u European Heart Journal (Europskom časopisu za srce) prošlo ljeto.
11:09
And it was just a pictogram
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To je bio piktogram
11:11
to sort of show
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kojim je prikazano
11:13
why more women are dying of heart disease,
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zašto žene umiru od srčane bolesti,
11:15
despite these good treatments
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unatoč tim dobrim terapijama
11:17
that we know and we have work.
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koje poznajemo i koje smo napravili.
11:20
And when the woman
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A kada žena
11:22
has male-pattern disease --
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ima muški obrazac bolesti --
11:24
so she looks like Barbara in the movie --
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pa izgleda kao Barbara u filmu --
11:27
they get treated.
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dobije tretman.
11:29
And when you have female-pattern and you look like a woman,
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A kad imate ženski obrazac i izgledate kao žena,
11:32
as Barbara does here with her husband,
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kao Barbara ovdje sa svojim mužem,
11:35
they don't get the treatment.
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ne dobijete tretman.
11:37
These are our life-saving treatments.
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Ovo su naši tretmani koji spašavaju život.
11:39
And those little red boxes are deaths.
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A ovi mali crveni kvadratići su umrli.
11:42
So those are the consequences.
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Dakle to su posljedice.
11:44
And that is female-pattern
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I ovo je ženski obrazac
11:46
and why we think the Yentl syndrome
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i zato mislimo kako Yentl sindrom
11:48
actually is explaining
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objašnjava
11:50
a lot of these gaps.
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mnoge rupe.
11:53
There's been wonderful news also
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Bilo je izvanrednih vijesti
11:56
about studying women,
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u konačnim istraživanjima
11:58
finally, in heart disease.
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žena sa srčanim bolestima.
12:00
And one of the the cutting-edge areas
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A jedno od najprogresivnijih područja
12:02
that we're just incredibly excited about
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oko kojega smo jako uzbuđeni
12:04
is stem cell therapy.
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je terapija matičnim stanicama.
12:06
If you ask, what is the big difference
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Ako se pitate koja je velika razlika
12:09
between women and men physiologically?
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između ženske i muške fiziologije?
12:11
Why are there women and men?
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Zašto postoje žene i muškarci?
12:14
Because women bring new life into the world.
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Ta što žene donose na svijet novi život.
12:17
That's all stem cells.
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Sve su to matične stanice.
12:19
So we hypothesized
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Pa smo pretpostavili
12:21
that female stem cells might be better
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kako bi ženske matične stanice mogle biti bolje
12:24
at identifying the injury,
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u prepoznavanju mjesta ozljede,
12:27
doing some cellular repair
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u nekakvom staničnom obnavljanju
12:29
or even producing new organs,
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ili čak u proizvodnji novih organa,
12:31
which is one of the things
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što je jedna od stvari
12:33
that we're trying to do with stem cell therapy.
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koju pokušavamo u terapiji s matičnim stanicama.
12:36
These are female and male stem cells.
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Ovo su muške i ženske matične stanice.
12:39
And if you had an injured organ,
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Pa ako imate oštećen organ,
12:41
if you had a heart attack
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ako ste imali srčani udar
12:43
and we wanted to repair that injured area,
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i želite popraviti oštećeno područje,
12:46
do you want those robust,
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želite li one gore --
12:48
plentiful stem cells on the top?
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snažne, izdašne stanice?
12:51
Or do you want these guys,
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Ili želite ove dečke
12:53
that look like they're out to lunch?
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koji izgledaju kao da su izašli na marendu?
12:55
(Laughter)
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(Smijeh)
12:57
And some of our investigative teams
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Neki istraživački timovi
13:00
have demonstrated
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pokazali su
13:02
that female stem cells --
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kako ženske matične stanice --
13:04
and this is in animals
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a to je na životinjama,
13:06
and increasingly we're showing this in humans --
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ali mi to sve više pokazujemo i na ljudima --
13:08
that female stem cells,
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dakle ženske matične stanice,
13:10
when put even into a male body,
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čak i kad se stave u muško tijelo,
13:12
do better than male stem cells
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rade bolje nego bi muške matične stanice
13:15
going into a male body.
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u muškom tijelu.
13:17
One of the things that we say
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Jedna od stvari koju uvijek kažemo
13:19
about all of this female physiology --
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o svoj toj ženskoj fiziologiji --
13:21
because again, as much as we're talking about women and heart disease,
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zato ponavljam, ma koliko govorili o ženama i srčanoj bolesti,
13:24
women do, on average,
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žene u prosjeku
13:26
have better longevity than men --
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žive dulje od muškaraca --
13:28
is that unfolding the secrets of female physiology
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razmotavanje tajni ženske fiziologije
13:31
and understanding that
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i razumijevanje,
13:33
is going to help men and women.
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pomoći će i muškarcima i ženama.
13:36
So this is not a zero-sum game in anyway.
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To svakako nije igra bez dobitka.
13:39
Okay, so here's where we started.
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OK, evo gdje smo počeli.
13:41
And remember, paths crossed in 1984,
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I sjetimo se, linije su se ukrstile 1984. godine,
13:45
and more and more women
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a sve više i više žena
13:47
were dying of cardiovascular disease.
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umiralo je od srčanih bolesti.
13:49
What has happened in the last 15 years with this work?
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Što se dogodilo u zadnjih 15 godina zahvaljujući tom radu?
13:52
We are bending the curve.
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Mi savijamo liniju.
13:54
We're bending the curve.
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Savijamo liniju.
13:56
So just like the breast cancer story,
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Baš kao u priči o tumoru dojke,
13:59
doing research, getting awareness going,
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istraživanjima, porast svijesti počinje djelovati,
14:02
it works, you just have to get it going.
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naprosto morate to pomaknuti.
14:05
Now are we happy with this?
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I jesmo li sada sretni postignutim?
14:07
We still have two to three more women dying for every man.
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Još uvijek imamo dvije do tri žene koje umiru na svakog muškarca.
14:10
And I would propose,
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Ja bih predložila,
14:12
with the better longevity
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uz dulji životni vijek
14:14
that women have overall,
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koji žene pretežno imaju,
14:16
that women probably should theoretically do better,
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da bi žene vjerojatno trebale teoretski biti bolje
14:18
if we could just get treated.
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kad bi samo dobile tretman.
14:20
So this is where we are,
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I ovo je gdje smo sada,
14:23
but we have a long row to hoe.
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ali nam ostaje dugačak rov za prokopati.
14:25
We've worked on this for 15 years.
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Radili smo na ovome 15 godina.
14:27
And I've told you, we've been working on male-pattern heart disease
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A rekla sam vam kako smo na muškom obrascu srčane bolesti radili
14:30
for 50 years.
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50 godina.
14:32
So we're 35 years behind.
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Dakle 35 godina smo u zaostatku.
14:34
And we'd like to think it's not going to take 35 years.
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A voljeli bismo vjerovati kako neće trajati 35 godina.
14:37
And in fact, it probably won't.
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A ustvari, vjerojatno i neće.
14:39
But we cannot stop now.
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Ali ne možemo sada stati.
14:41
Too many lives are at stake.
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Previše života je u pitanju.
14:44
So what do we need to do?
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Pa što nam je činiti?
14:47
You now, hopefully, have a more personal relationship
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Vi sada, nadajmo se, imate osobniji odnos
14:49
with your heart.
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sa svojim srcem.
14:51
Women have heard the call
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Žene su čule poziv
14:53
for breast cancer
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protiv tumora dojke
14:55
and they have come out
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pa su izašle
14:57
for awareness campaigns.
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na kampanje podizanja svjesnosti.
14:59
The women are very good about getting mammograms now.
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Žene su sada jako dobre u odlascima na mamografiju.
15:02
And women do fundraising.
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I žene prikupljaju novac.
15:04
Women participate.
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Žene sudjeluju.
15:06
They have put their money where their mouth is
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Uložile su svoj novac u ono o čemu su govorile,
15:08
and they have done advocacy and they have joined campaigns.
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zagovarale su i pridružile se kampanjama.
15:11
This is what we need to do with heart disease now.
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To je ono što sada trebamo učiniti sa srčanom bolešću.
15:14
And it's political.
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A to je politika.
15:16
Women's health, from a federal funding standpoint,
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Žensko zdravlje sa stajališta federalnog financiranja,
15:19
sometimes it's popular,
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ponekad je popularno,
15:21
sometimes it's not so popular.
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a ponekad i nije.
15:24
So we have these feast and famine cycles.
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I zato imamo cikluse obilja i gladi.
15:26
So I implore you
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I zato vas molim
15:28
to join the Red Dress Campaign
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da se pridružite Kampanji crvenih haljina
15:30
in this fundraising.
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u ovom prikupljanju fondova.
15:32
Breast cancer, as we said,
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Tumor dojke, kao što smo rekli,
15:34
kills women,
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ubija žene,
15:36
but heart disease kills a whole bunch more.
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ali srčane bolesti ih ubijaju neizmjerno više.
15:39
So if we can be as good as breast cancer
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Pa ako bi smo mogli biti dobri kao kod tumora dojke
15:41
and give women this new charge,
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i dati ženama taj novi naboj,
15:43
we have a lot of lives to save.
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spasili bismo mnoge živote.
15:45
So thank you for your attention.
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Zahvaljujem na pozornosti.
15:47
(Applause)
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(Pljesak)
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Ova stranica će vas upoznati s YouTube videozapisima koji su korisni za učenje engleskog jezika. Vidjet ćete lekcije engleskog koje vode vrhunski profesori iz cijelog svijeta. Dvaput kliknite na engleske titlove prikazane na svakoj video stranici da biste reproducirali video s tog mjesta. Titlovi se pomiču sinkronizirano s reprodukcijom videozapisa. Ako imate bilo kakvih komentara ili zahtjeva, obratite nam se putem ovog obrasca za kontakt.

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