How does the thyroid manage your metabolism? - Emma Bryce

1,079,040 views ・ 2015-03-02

TED-Ed


Please double-click on the English subtitles below to play the video.

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Nestled in the tissues of your neck is a small unassuming organ
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that wields enormous power over your body.
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It's called the thyroid.
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Like the operations manager in a company,
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its role is to make sure that the cells in your body are working properly.
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It does that by using hormones to deliver messages to every single one of them.
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This high-ranking organ is made up of lobules
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that each contains smaller cells called follicles,
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which store the hormones the thyroid sends out into your blood.
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Two of the most important hormones it produces
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are thyroxine and triiodothyronine, or T3 and T4.
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As messengers, the hormone's job
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is to instruct every cell in the body when to consume oxygen and nutrients.
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That maintains the body's metabolism,
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the series of reactions our cells perform to provide us with energy.
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This hormonal notification from the thyroid
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gets the heart pumping more efficiently,
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and makes our cells break down nutrients faster.
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When you need more energy,
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the thyroid helps by sending out hormones to increase metabolism.
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Ultimately, the thyroid allows our cells to use energy, grow and reproduce.
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The thyroid is controlled by the pituitary gland,
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a hormonal gland deep in the brain that oversees the thyroid's tasks,
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making sure it knows when to send out its messengers.
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The pituitary's role is to sense if hormone levels in the blood
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are too low or too high,
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in which case it sends out instructions
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in the form of the thyroid- stimulating hormone.
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Even in this tightly controlled system, however,
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management sometimes slips up.
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Certain diseases,
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growths in the thryoid
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or chemical imbalances in the body can confuse the organ
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and make it deaf to the pituitary's guiding commands.
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The first problem this causes is hyperthyroidism,
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which happens when the organ sends out too many hormones.
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That means the cells are overloaded with instructions
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to consume nutrients and oxygen.
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They become overactive as a result,
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meaning a person with hyperthyroidism experiences a higher metabolism
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signaled by a faster heartbeat, constant hunger, and rapid weight loss.
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They also feel hot, sweaty, anxious, and find it difficult to sleep.
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The opposite problem is hypothyroidism,
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which happens when the thyroid sends out too few hormones,
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meaning the body's cells don't have as many messengers to guide them.
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In response, cells grow listless and metabolism slows.
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People with hypothyroidism see symptoms in weight gain,
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sluggishness, sensitivity to cold, swollen joints and feeling low.
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Luckily, there are medical treatments
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that can help trigger the thyroid's activities again,
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and bring the body back to a steady metabolic rate.
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For such a little organ, the thyroid wields an awful lot of power.
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But a healthy thyroid manages our cells so effectively
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that it can keep us running smoothly without us even noticing it's there.
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