What makes muscles grow? - Jeffrey Siegel

21,617,578 views ・ 2015-11-03

TED-Ed


Please double-click on the English subtitles below to play the video.

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Muscles.
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We have over 600 of them.
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They make up between 1/3 and 1/2 of our body weight,
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and along with connective tissue,
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they bind us together, hold us up, and help us move.
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And whether or not body building is your hobby,
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muscles need your constant attention
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because the way you treat them on a daily basis
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determines whether they will wither or grow.
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Say you're standing in front of a door, ready to pull it open.
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Your brain and muscles are perfectly poised to help you achieve this goal.
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First, your brain sends a signal to motor neurons inside your arm.
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When they receive this message, they fire,
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causing muscles to contract and relax,
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which pull on the bones in your arm and generate the needed movement.
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The bigger the challenge becomes, the bigger the brain's signal grows,
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and the more motor units it rallies to help you achieve your task.
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But what if the door is made of solid iron?
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At this point, your arm muscles alone
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won't be able to generate enough tension to pull it open,
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so your brain appeals to other muscles for help.
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You plant your feet, tighten your belly, and tense your back,
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generating enough force to yank it open.
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Your nervous system has just leveraged the resources you already have,
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other muscles,
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to meet the demand.
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While all this is happening,
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your muscle fibers undergo another kind of cellular change.
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As you expose them to stress, they experience microscopic damage,
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which, in this context, is a good thing.
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In response, the injured cells release inflammatory molecules called cytokines
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that activate the immune system to repair the injury.
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This is when the muscle-building magic happens.
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The greater the damage to the muscle tissue,
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the more your body will need to repair itself.
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The resulting cycle of damage and repair
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eventually makes muscles bigger and stronger
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as they adapt to progressively greater demands.
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Since our bodies have already adapted to most everyday activities,
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those generally don't produce enough stress
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to stimulate new muscle growth.
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So, to build new muscle, a process called hypertrophy,
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our cells need to be exposed to higher workloads than they are used to.
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In fact, if you don't continuously expose your muscles to some resistance,
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they will shrink,
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a process known as muscular atrophy.
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In contrast, exposing the muscle to a high-degree of tension,
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especially while the muscle is lengthening,
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also called an eccentric contraction,
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generates effective conditions for new growth.
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However, muscles rely on more than just activity to grow.
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Without proper nutrition, hormones, and rest,
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your body would never be able to repair damaged muscle fibers.
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Protein in our diet preserves muscle mass
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by providing the building blocks for new tissue
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in the form of amino acids.
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Adequate protein intake, along with naturally occurring hormones,
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like insulin-like growth factor and testosterone,
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help shift the body into a state where tissue is repaired and grown.
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This vital repair process mainly occurs when we're resting,
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especially at night while sleeping.
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Gender and age affect this repair mechanism,
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which is why young men with more testosterone
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have a leg up in the muscle building game.
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Genetic factors also play a role in one's ability to grow muscle.
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Some people have more robust immune reactions to muscle damage,
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and are better able to repair and replace damaged muscle fibers,
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increasing their muscle-building potential.
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The body responds to the demands you place on it.
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If you tear your muscles up, eat right, rest and repeat,
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you'll create the conditions to make your muscles as big and strong as possible.
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It is with muscles as it is with life:
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Meaningful growth requires challenge and stress.
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