How do vitamins work? - Ginnie Trinh Nguyen

6,304,802 views ・ 2014-10-06

TED-Ed


Please double-click on the English subtitles below to play the video.

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A, C, E, D, B, K.
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No, this isn't some random, out of order alphabet.
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These are vitamins, and just like letters build words,
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they're the building blocks that keep the body running.
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Vitamins are organic compounds we need to ingest in small amounts
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to keep functioning.
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They're the body's builders, defenders and maintenance workers,
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helping it to build muscle and bone, make use of nutrients,
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capture and use energy and heal wounds.
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If you need convincing about vitamin value,
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just consider the plight of olden day sailors,
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who had no access to vitamin-rich fresh produce.
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They got scurvy.
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But vitamin C, abundant in fruits and vegetables,
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was the simple antidote to this disease.
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While bacteria, fungi and plants produce their own vitamins,
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our bodies can't, so we have to get them from other sources.
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So how does the body get vitamins from out there into here?
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That's dependent on the form these compounds take.
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Vitamins come in two types:
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lipid-soluble and water-soluble,
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and the difference between them determines how the body
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transports and stores vitamins, and gets rid of the excess.
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The water-solubles are vitamin C
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and B Complex vitamins that are made up of eight different types
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that each do something unique.
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These are dissolved in the watery parts of fruits, vegetables and grains,
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meaning their passage through the body is relatively straightforward.
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Once inside the system, these foods are digested
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and the vitamins within them are taken up directly by the bloodstream.
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Because blood plasma is water-based,
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water-soluble vitamins C and B have their transport cut out for them
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and can move around freely within the body.
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For lipid-soluble vitamins, dissolved in fat
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and found in foods like diary, butter and oils,
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this trip into the blood is a little more adventurous.
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These vitamins make it through the stomach and the intestine,
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where an acidic substance called bile flows in from the liver,
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breaking up the fat and preparing it for absorption through the intestinal wall.
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Because fat-soluble vitamins can't make use of the blood's watery nature,
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they need something else to move them around,
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and that comes from proteins that attach to the vitamins and act like couriers,
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transporting fat-solubles into the blood and around the body.
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So, this difference between water- or fat-soluble vitamins
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determines how they get into the blood,
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but also how they're stored or rejected from the body.
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The system's ability to circulate water-soluble vitamins
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in the bloodstream so easily
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means that most of them can be passed out equally easily via the kidneys.
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Because of that, most water-soluble vitamins
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need to be replenished on a daily basis through the food we eat.
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But fat-soluble vitamins have staying power
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because they can be packed into the liver and in fat cells.
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The body treats these parts like a pantry,
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storing the vitamins there and rationing them out when needed,
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meaning we shouldn't overload on this type of vitamin
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because the body is generally well stocked.
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Once we figured the logistics of transport and storage,
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the vitamins are left to do the work they came here to do in the first place.
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Some, like many of the B Complex vitamins, make up coenzymes,
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whose job it is to help enzymes release the energy from food.
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Other B vitamins then help the body to use that energy.
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From vitamin C, you get the ability to fight infection and make collagen,
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a kind of tissue that forms bones and teeth and heals wounds.
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Vitamin A helps make white blood cells, key in the body's defense,
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helps shape bones and improves vision by keeping the cells of the eye in check.
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Vitamin D gathers calcium and phosphorus so we can make bones,
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and vitamin E works as an antioxidant,
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getting rid of elements in the body that can damage cells.
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Finally, from Vitamin K, we score the ability to clot blood,
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since it helps make the proteins that do this job.
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Without this vitamin variety,
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humans face deficiencies that cause a range of problems,
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like fatigue, nerve damage, heart disorders,
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or diseases like rickets and scurvy.
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On the other hand, too much of any vitamin can cause toxicity in the body,
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so there goes the myth that loading yourself with supplements is a great idea.
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In reality, it's all about getting the balance right,
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and hitting that vitamin jackpot.
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