What does the pancreas do? - Emma Bryce

1,082,547 views ・ 2015-02-19

TED-Ed


Please double-click on the English subtitles below to play the video.

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Beneath your ribs, you'll find, among other things, the pancreas,
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an organ that works a lot like a personal health coach.
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This organ controls your sugar levels and produces a special juice
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that releases the nutrients from your food
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to help keep you in the best possible shape.
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The pancreas sits just behind your stomach,
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an appropriate home, as one of its jobs is to break down the food you eat.
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It aids digestion by producing a special tonic made of water,
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sodium bicarbonate,
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and digestive enzymes.
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Sodium bicarbonate neutralizes the stomach's natural acidity,
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so these digestive enzymes can perform their jobs.
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Lipase breaks down fatty substances,
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protease splits up proteins,
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and amylase divides carbohydrates to create energy-rich sugars.
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Most of those nutrients then get absorbed into the blood stream,
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and go on to enrich the body.
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While all this is happening, the pancreas works on another critical task,
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controlling the amount of sugar in your blood.
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It achieves this with the hormones insulin and glucagon,
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which are produced in special cells called the Islets of Langerhans.
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Having too much or too little sugar can be life threatening,
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so the pancreas must stay on constant alert.
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After a big meal, the blood often becomes flushed with sugar.
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To bring us back to normal, the pancreas releases insulin,
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which makes the excess sugar move into cells,
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where it's either used as an energy source, or stored for later.
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Insulin also tells the liver to shut down sugar production.
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On the other hand, if blood sugar is low,
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the pancreas releases a hormone called glucagon
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that tells the body's cells and liver to release stored sugars
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back into the bloodstream.
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The interplay between insulin and glucagon is what keeps our sugar levels balanced.
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But a faulty pancreas can no longer coach us like this,
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meaning that this healthy balance is destroyed.
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If it's weakened by disease,
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the organ's ability to produce insulin may be reduced, or even extinguished,
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which can trigger the condition known as diabetes.
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Without regular insulin release, sugar steadily builds up in the blood,
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eventually hardening the blood vessels and causing heart attacks,
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kidney failure,
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and strokes.
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The same lack of insulin deprives cells of the energy-rich sugar
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they need to grow and function.
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People with diabetes also tend to have higher levels of glucagon,
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which makes even more sugar circulate.
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Without this internal health coach, our sugar levels would go haywire,
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and we wouldn't be able to digest important nutrients.
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But like any coach,
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it's not the pancreas' job alone to keep us healthy.
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It needs our conscious participation, too.
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