Can you still feel a limb that's gone? - Joshua W. Pate

831,471 views ・ 2018-10-04

TED-Ed


請雙擊下方英文字幕播放視頻。

譯者: Lilian Chiu 審譯者: Helen Chang
00:06
The vast majority of people who’ve lost a limb can still feel it—
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大部分斷肢的人還可以 感覺到斷肢的存在——
00:11
not as a memory or vague shape, but in complete lifelike detail.
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並不是記憶或是模糊的形狀,
而是有很完整很逼真的細節。
00:16
They can flex their phantom fingers
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他們能夠彎曲他們的幻指,
00:19
and sometimes even feel the chafe of a watchband
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有時甚至能感覺到錶帶的磨擦,
00:22
or the throb of an ingrown toenail.
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或是腳趾甲向內生長帶來的刺痛。
00:25
And astonishingly enough,
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很驚人的是,
00:27
occasionally even people born without a limb can feel a phantom.
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偶爾,即使出生時就沒有肢體的人
也能感覺到幻肢。
00:33
So what causes phantom limb sensations?
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所以,是什麼造成幻肢的感覺?
00:36
The accuracy of these apparitions
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這些幻覺的精準度
00:38
suggests that we have a map of the body in our brains.
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意味著我們的大腦中 有一張身體地圖。
00:42
And the fact that it’s possible
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因為連從來沒有肢體的人
00:43
for someone who’s never had a limb to feel one
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也能感受到幻肢,
00:46
implies we are born with at least the beginnings of this map.
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就表示我們在出生時至少 就有一張初版的身體地圖了。
00:51
But one thing sets the phantoms that appear after amputation
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但截肢之後出現的幻肢
和原本的血肉肢體有一個差別:
00:55
apart from their flesh and blood predecessors:
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00:58
the vast majority of them are painful.
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大部分關於幻肢的感覺是痛苦的。
01:01
To fully understand phantom limbs and phantom pain,
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若要完全了解幻肢和幻痛,
01:05
we have to consider the entire pathway from limb to brain.
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我們必須要思考從肢體 到大腦的整條路徑。
01:09
Our limbs are full of sensory neurons responsible for everything
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我們的肢體佈滿很多感覺神經元,
負責的功能很多, 從指尖感受到的質地,
01:13
from the textures we feel with our fingertips
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01:16
to our understanding of where our bodies are in space.
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到我們對於身體在空間中 相對位置的理解。
01:20
Neural pathways carry this sensory input through the spinal cord
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神經傳導路徑會把這些 感覺輸入訊號透過脊髓
01:24
and up to the brain.
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向上傳到大腦。
01:26
Since so much of this path lies outside the limb itself,
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因為這路徑有很大部分在四肢之外,
01:30
most of it remains behind after an amputation.
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大部分路徑在截肢之後還存留著。
01:34
But the loss of a limb
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但失去了肢體就會改變
01:35
alters the way signals travel at every step of the pathway.
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訊號在路徑中每一步的傳導方式。
01:40
At the site of an amputation,
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在截肢處,
01:42
severed nerve endings can thicken and become more sensitive,
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被切斷的神經末稍可能會 變粗,變得更敏感,
01:46
transmitting distress signals even in response to mild pressure.
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輕微的壓力,就會讓它 傳送出痛苦的訊號。
01:50
Under normal circumstances,
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在正常情況下,
01:52
these signals would be curtailed in the dorsal horn of the spinal cord.
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這些訊號會被脊髓背角給削減掉。
01:56
For reasons we don’t fully understand, after an amputation,
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但由於某些我們還不全然 了解的理由,在截肢後,
02:00
there is a loss of this inhibitory control in the dorsal horn,
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背角中的這種抑制 控制功能會消失,
02:05
and signals can intensify.
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訊號可能會變強。
02:08
Once they pass through the spinal cord, sensory signals reach the brain.
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一旦感覺訊號通過了脊髓, 就會抵達大腦。
02:13
There, the somatosensory cortex processes them.
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在大腦中,感覺皮質 會負責處理這些訊號。
02:17
The entire body is mapped in this cortex.
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這個皮質區有整個身體的地圖。
02:20
Sensitive body parts with many nerve endings,
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因為有許多神經末稍 所以很敏感的身體部位,
02:23
like the lips and hands,
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像是嘴脣和手,
02:25
are represented by the largest areas.
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是由最大塊的區域來代表。
02:27
The cortical homunculus is a model of the human body
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皮質小人是一種人體模型,
02:30
with proportions based on the size of each body part’s representation in the cortex,
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身體部位的比例是根據它們
在皮質區中對應的大小。
02:36
The amount of cortex devoted to a specific body part can grow or shrink
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每個身體部位對應的皮質代表區
可能會長大或縮小,
02:41
based on how much sensory input the brain receives from that body part.
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依據是看大腦接收的感覺輸入訊號 有多少是來自那個身體部位。
02:46
For example, representation of the left hand is larger in violinists
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以左手對應的皮質代表區為例,
小提琴家的這個區域 就會比一般人還大。
02:51
than in non-violinists.
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02:53
The brain also increases cortical representation
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當一個身體部位受傷時,
大腦也會增加對應的皮質代表區,
02:56
when a body part is injured
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02:58
in order to heighten sensations that alert us to danger.
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以強化該部位的感覺, 來警告我們可能的危險。
03:02
This increased representation can lead to phantom pain.
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代表區的增加,就可能造成幻痛。
03:06
The cortical map is also most likely responsible
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會感覺到已經不存在的身體部位,
03:09
for the feeling of body parts that are no longer there,
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也很有可能是皮質地圖造成的,
03:13
because they still have representation in the brain.
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因為在大腦中還是有 那些部位對應的代表區。
03:16
Over time, this representation may shrink and the phantom limb may shrink with it.
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隨時間過去,代表區可能會縮小,
幻肢的狀況也可能隨之減輕。
03:22
But phantom limb sensations don’t necessarily disappear on their own.
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但幻覺的感覺 不見得都會自己消失。
03:26
Treatment for phantom pain usually requires
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若要治療幻痛,通常會需要
03:29
a combination of physical therapy,
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結合物理治療、止痛藥物、
03:31
medications for pain management,
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03:33
prosthetics,
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假肢,和時間。
03:34
and time.
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有一種叫做鏡箱治療的技術,
03:36
A technique called mirror box therapy
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03:38
can be very helpful in developing the range of motion
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對於發展動作範圍
及減輕幻肢痛楚都很有幫助。
03:41
and reducing pain in the phantom limb.
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03:43
The patient places the phantom limb into a box behind a mirror
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病人要把幻肢放入 鏡子後面的箱子內,
03:48
and the intact limb in front of the mirror.
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好的肢體放在鏡子前面。
03:50
This tricks the brain into seeing the phantom
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這能欺騙大腦, 讓大腦以為看見了幻肢,
03:53
rather than just feeling it.
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而不只是感覺到幻肢。
03:55
Scientists are developing virtual reality treatments
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科學家正在開發虛擬境的治療法,
03:59
that make the experience of mirror box therapy even more lifelike.
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讓鏡箱治療的體驗能變得更真實。
04:03
Prosthetics can also create a similar effect—
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假肢也能產生類似的效果——
04:06
many patients report pain
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許多病人說自己主要是在晚上
04:08
primarily when they remove their prosthetics at night.
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把假肢拿掉之後才會感到痛楚。
04:11
And phantom limbs may in turn
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幻肢有可能會反過來
04:13
help patients conceptualize prosthetics as extensions of their bodies
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協助病人將假肢給概念化,
視為是身體的延伸部分,
04:18
and manipulate them intuitively.
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並以直覺的方式來操控假肢。
04:21
There are still many questions about phantom limbs.
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關於幻肢,還有許多沒解開的謎。
04:24
We don’t know why some amputees escape the pain
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我們不知道為什麼有些被截肢者
沒有通常伴隨著幻肢的痛楚,
04:27
typically associated with these apparitions,
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04:30
or why some don’t have phantoms at all.
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也不知道為什麼有些人 根本不會有幻覺。
04:32
And further research into phantom limbs
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關於幻肢的進一步研究
04:35
isn’t just applicable to the people who experience them.
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不僅僅是針對感受到幻肢的人。
04:38
A deeper understanding of these apparitions
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若能對這類幻覺有更深的了解,
04:40
will give us insight into the work our brains do every day
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我們就能更清楚大腦 每天會做些什麼工作
04:45
to build the world as we perceive it.
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來建立出我們所感知到的世界。
04:47
They’re an important reminder
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它們是個重要的提醒,
04:49
that the realities we experience are, in fact, subjective.
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提醒我們,我們所體驗到的現實,
其實都是主觀的。
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