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譯者: Regina Chu
審譯者: Marssi Draw
00:07
At some point,
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遲早有一天
00:08
most sexually active people will be
infected with human papillomavirus,
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大多數性活躍的人
會感染人類乳突病毒
00:12
or ‘HPV.’
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又稱 HPV
00:13
There are over 100 types of HPV,
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目前有超過一百種 HPV
00:16
and most of the time the body
eliminates infections without symptoms–
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通常身體會消滅感染
而且不會出現任何臨床症狀
00:20
but some strains can pose serious
health risks down the line.
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但是某些毒株會進一步
對健康造成嚴重威脅
00:23
HPV causes contact infections,
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HPV 會引起接觸感染
00:26
which means the virus stays in the cells
near the point of infection
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亦即病毒會待在感染處附近的細胞內
00:30
rather than spreading throughout
the whole body.
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而不是散播至全身
00:32
Since HPV is often transmitted through
sexual activity,
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因為 HPV 通常經由性行為傳染
00:36
this usually means the cells of the
vagina, vulva, penis, anus,
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這通常是指陰道、外陰、陰莖、肛門
00:40
mouth and throat.
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口腔及喉嚨細胞
00:41
We can test for HPV in cells from
these areas,
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我們可以從這些地方的細胞檢驗 HPV
00:44
but while testing for the virus
is scientifically possible,
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但是即使可以用科學方法
檢驗到這種病毒
00:47
it isn’t common.
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通常也不這麼做
00:49
The main reason is that,
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主要的原因是
00:50
while there are treatments for the
adverse health effects caused by HPV,
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雖然有方法能治療 HPV
對健康引起的不良影響
00:54
there’s no treatment for the virus itself.
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卻沒有方法能治療病毒本身
00:56
So testing for HPV would yield many,
many positives,
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所以做 HPV 檢驗可能會產生
非常非常多的陽性反應
01:00
and although most of them won’t
be cause for concern,
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雖然大多數不會造成問題
01:02
there is still no treatment plan for
clearing the body of the virus.
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仍然沒有治療計畫能清除病毒
01:07
But there are other good ways to
protect yourself from HPV.
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但是還是有其它方法
保護自己免受 HPV 傷害
01:10
We’re going to walk through how
HPV can cause harm,
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我們就來談談 HPV 如何造成傷害
01:13
who’s at risk, and how to
minimize those risks.
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誰有風險及如何降低風險
01:17
The body’s immune system is able to
eradicate most strains of HPV
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身體的免疫系統
可以消滅大多數種 HPV 毒株
01:21
before they cause any harm—
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不讓它們引起傷害
01:23
and without people even knowing
they’ve been infected.
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有些人甚至不知道他們已經被感染了
01:26
Certain other strains–
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某些特定毒株
01:28
like HPV 6 and 11–
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如 HPV 6 及 HPV 11
01:30
cause abnormalities in the cells of the
infected tissue,
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會造成受感染組織的細胞異常
01:33
which can develop into genital warts.
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可能發展成性器疣
01:36
While these are infectious
and require treatment,
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這些疣具傳染性並需要治療
01:39
usually with topical creams,
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通常是用外用藥膏
01:41
wart-causing strains don’t create
longer-term damage.
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會造成疣的毒株不會產生長期危害
01:45
But another 13 strains can cause DNA
mutations that cause cells to divide
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但是另外有十三種毒株
會造成 DNA 突變
使細胞分裂的速度比正常更快
01:49
at a much faster pace than normal,
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01:52
propelling the development of
cancerous growths.
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助長癌細胞生長
01:55
The cells of the cervix are
especially at risks.
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子宮頸細胞的風險特別大
01:57
Two in particular–
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特別有兩種毒株
01:59
HPV 16 and 18–
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HPV 16 及 HPV 18
02:01
are responsible for the majority of
cases of cervical cancer,
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為造成大多數子宮頸癌的主因
02:05
which is now the fourth most common
type of cancer in women.
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這是現今第四大的婦女癌症
02:08
It can take up to 20 years for cancer
symptoms to appear,
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癌症可能要長達 20 年
才會出現症狀
02:12
but with regular screening,
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如果定期檢查
02:13
we can discover cellular abnormalities
in the cervix
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我們可以發現子宮頸細胞異常
02:16
before they develop into cancer.
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在它們發展成癌症前就看出來
02:19
Women over 21 can undergo a regular
pap smear,
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21 歲以上的婦女
可以定期做子宮頸抹片檢查
02:22
where a sample of tissue is gently
scraped from the lining of the cervix
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即在子宮頸內膜輕輕刮下組織檢體
02:25
to test for abnormal cells.
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檢查是否有變異細胞
02:28
A positive test doesn’t mean the person
has cervical cancer,
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陽性結果並不代表這個人有子宮頸癌
02:31
but rather that there are irregular
cells in the cervix
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而是子宮頸有不正常的細胞
02:34
that could develop into cancer
in the future.
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可能在未來發展成癌症
02:37
Patients are then either monitored
with more frequent pap smears,
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之後病患可能要
更常做抹片檢查以監測變異
02:40
or, for more severe irregularities,
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如果變異情況較嚴重
02:43
undergo a procedure called a colposcopy.
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就會做陰道鏡檢查
02:45
This involves a doctor examining the
cervix through a microscope,
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這需要醫師用顯微鏡做子宮頸檢查
02:49
and possibly taking a small biopsy of
tissue for closer examination.
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並有可能取組織切片以更仔細檢查
02:54
In some cases, the affected tissue
may be removed.
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在某些情況下
受影響的組織可能會被切除
02:58
HPV infections of the throat may lead to
head and neck cancers,
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喉嚨感染 HPV 可能會導致頭頸癌
03:02
but for now there’s no equivalent of the
pap smear for the throat.
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但是目前沒有相應的喉嚨抹片檢查
03:05
Using condoms helps prevent
the spread of HPV during sex.
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使用保險套可以幫助避免
在性交時傳播 HPV
03:09
And there are three safe, effective
vaccines that all target HPV 16 and 18.
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目前有三種安全有效的疫苗
專門針對 HPV 16 及 HPV 18
03:15
The vaccine comes in two or three doses
a few months apart,
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這個疫苗分二至三劑施打
每次相隔幾個月
03:19
and it’s only beneficial if you
receive them all.
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要全部打完才有用
03:22
Right now the vaccine is part of standard
care for girls aged 11 to 18
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目前這種疫苗
在許多國家是 11 至 18 歲女孩
健保計畫的一部分
03:27
in many countries–
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03:28
though it’s increasingly becoming
available to boys as well.
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也有愈來愈多的男孩接種
03:31
Adult women and men in countries including
the United States and the United Kingdom
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在美國及英國等許多國家的
成年女性及男性
03:36
can opt to receive the vaccine,
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也可以選擇接種疫苗
03:38
and evidence suggests that vaccination of
women and men
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證據顯示女性及男性接種疫苗
03:41
could reduce the worldwide incidence of
cervical cancer by almost 90%.
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可以在全世界減少
幾乎 90% 的子宮頸癌
03:46
Researchers are also
developing an injection
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研究人員也發展出注射針劑
03:49
for people who are already infected
with HPV 16 and 18,
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給已經感染了 HPV 16 及 18 的人
03:52
which would target the infected cells
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它會標靶受感染的細胞
03:54
to stop them from developing
into cancerous ones.
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不讓它們發展成癌細胞
03:57
So while there’s still room for
improvement in screening,
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所以即使篩檢、治療及接種計畫
都還有進步的空間
04:00
treatment, and access to each,
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04:02
condom use, vaccination,
and cervical screening
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使用保險套、接種疫苗及子宮頸篩檢
04:05
can each reduce the harm caused by HPV.
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都可以減低 HPV 造成的傷害
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