What causes heartburn? - Rusha Modi

1,821,937 views ・ 2018-11-01

TED-Ed


Please double-click on the English subtitles below to play the video.

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Just between your chest and abdomen
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is where you’ll find one of the most important muscles
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you probably didn't know you had:
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the lower esophageal sphincter, or LES.
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When functioning properly,
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this ring of tissue plays a crucial role in helping us eat.
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But when the LES malfunctions,
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it becomes the main player in heartburn
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--a searing, sometimes sour-tasting chest-spasm
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that many people will experience at some point in their lives.
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We know that humans have been battling heartburn
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for hundreds, if not thousands of years.
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But recently the incidence has risen,
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making it a common stomach complaint worldwide.
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When the symptoms of heartburn become more more regular and intense
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—such as twice a week or more--
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it’s diagnosed as Gastroesophageal Reflux Disease, or GERD.
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But what causes this problem,
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and how can it be stopped?
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Heartburn starts in an area called
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the gastroesophageal junction, where the LES resides.
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This smooth, muscular ring of the LES
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is moderated by an intricate tree of nerve roots
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that connect to the brain, the heart, and the lungs.
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After food enters the stomach from the esophagus,
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the muscle’s task is to stop it
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from surging back up again.
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The LES contracts, squeezing the stomach entrance
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and creating a high pressure zone
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that prevents digestive acids from seeping out.
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But if the LES relaxes at the wrong moment or gradually weakens,
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it becomes like a faulty, ill-fitting lid,
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causing the area to depressurize.
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That allows burning stomach acid--
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and even chunks of food--to spurt into the
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esophagus, sometimes going as far up as the mouth.
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The cause of all this internal drama
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has long been put down to diet.
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Foods like caffeine and peppermint contain
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ingredients that may have a relaxing affect on the LES,
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which makes it incapable of doing its job.
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Other acidic foods, like citrus and tomatoes,
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can worsen irritation of the esophagus
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when they leach out with stomach acid.
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Carbonated beverages can similarly
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bubble up in the stomach,
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forcing open the valve.
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But researchers have discovered that food isn’t the only trigger.
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Smoking poses a risk, because the nicotine in cigarettes relaxes the LES.
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Consuming excessive amounts of alcohol
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may have a similar effect.
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Pregnant women often experience more heartburn
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due to the pressure of a growing baby on their stomachs.
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and the levels of certain hormones in their bodies.
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Obesity can cause hernias that disrupt
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the anti-reflux barrier of the gastroesophageal junction
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that normally protects against heartburn.
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Numerous medications, including those for asthma,
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high blood pressure, birth control, and depression
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can also have unintended effects on the LES.
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An occasional bout of heartburn isn't
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necessarily something to worry about.
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But, if heartburn starts happening regularly,
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it can weaken the LES muscle over time,
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letting more and more acid escape.
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And if it goes untreated,
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this can cause bigger problems.
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Over time, constant acid leakage from heartburn
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may form scar tissue which narrows the
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esophageal tube, making it harder to swallow food.
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Ongoing reflux can also damage the cells
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lining the esophagus--a rare condition called
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Barrett’s esophagus, which can elevate
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the risk of esophageal cancer.
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Luckily, heartburn is often treatable with
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a range of medicines that can help
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neutralize or reduce stomach acid.
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In extreme cases, some people have surgery
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to tighten the LES to minimize their distress.
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But we can often stop heartburn
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before it reaches that point.
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Reducing the consumption of certain foods,
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not smoking, and maintaining a healthy weight
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can all dramatically reduce reflux.
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With proper care we can help our LES’s keep
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the chemical fountain of our stomachs in proper order
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and avoid having to feel the burn.
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