How digital DNA could help you make better health choices | Jun Wang

66,372 views ใƒป 2017-10-02

TED


ูŠุฑุฌู‰ ุงู„ู†ู‚ุฑ ู†ู‚ุฑู‹ุง ู…ุฒุฏูˆุฌู‹ุง ููˆู‚ ุงู„ุชุฑุฌู…ุฉ ุงู„ุฅู†ุฌู„ูŠุฒูŠุฉ ุฃุฏู†ุงู‡ ู„ุชุดุบูŠู„ ุงู„ููŠุฏูŠูˆ.

ุงู„ู…ุชุฑุฌู…: Mahdi Salem ุงู„ู…ุฏู‚ู‘ู‚: Hani Eldalees
00:12
Today I'm here, actually, to pose you a question.
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ุฃู†ุง ู‡ู†ุง ุงู„ูŠูˆู… ู„ุฃุทุฑุญ ุนู„ูŠูƒู… ุณุคุงู„ุง.
00:15
What is life?
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ู…ุง ู‡ูŠ ุงู„ุญูŠุงุฉุŸ
00:17
It has been really puzzling me for more than 25 years,
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ุฅู†ู‡ุง ุญู‚ุง ุชุญูŠุฑู†ูŠ ู…ู†ุฐ ุฃูƒุซุฑ ู…ู† 25 ุนุงู…ุงุŒ
00:21
and will probably continue doing so for the next 25 years.
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ูˆุฑุจู…ุง ุชุณุชู…ุฑ ูƒุฐู„ูƒ ุทูˆุงู„ 25 ุณู†ุฉู‹ ุฃุฎุฑู‰.
00:25
This is the thesis I did when I was still in undergraduate school.
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ู‡ุฐุง ุงู„ุจุญุซ ุนู…ู„ุชู‡ ุนู†ุฏู…ุง ูƒู†ุช ุทุงู„ุจุงู‹ ุจุงู„ุฌุงู…ุนุฉ.
00:31
While my colleagues still treated computers as big calculators,
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ุนู†ุฏู…ุง ูƒุงู† ุฒู…ู„ุงุฆูŠ ูŠุนุงู…ู„ูˆู† ุงู„ูƒู…ุจูŠูˆุชุฑ ุนู„ู‰ ุฃู†ู‡ ุขู„ุฉูŒ ุญุงุณุจุฉูŒ ูƒุจูŠุฑุฉุŒ
00:38
I started to teach computers to learn.
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ุจุฏุฃุช ุฃุฏุฑูุณ ุงู„ูƒู…ุจูŠูˆุชุฑ ู„ุฃุชุนู„ู….
00:41
I built digital lady beetles
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ู‚ู…ุช ุจุจู†ุงุก ุฎู†ูุณุฉู ุฑู‚ู…ูŠุฉ
00:44
and tried to learn from real lady beetles, just to do one thing:
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ูˆุญุงูˆู„ุช ุงู„ุชุนู„ูู… ู…ู† ุฎู†ูุณุงุกู ุญู‚ูŠู‚ูŠุฉุŒ ูู‚ุท ู„ุฃูุนู„ ุดูŠุฆุงู‹ ูˆุงุญุฏุงู‹:
00:49
search for food.
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ุงู„ุจุญุซ ุนู† ุงู„ุทุนุงู….
00:51
And after very simple neural network --
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ูˆุจุนุฏ ุดุจูƒุฉู ุนุตุจูŠุฉู ุจุณูŠุทุฉ--
00:53
genetic algorithms and so on --
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ู„ูˆุบุงุฑูŠุซู…ูŠูŽุฉู ุฌูŠู†ูŠูŽุฉุŒ ูˆู…ุง ุฅู„ู‰ ุฐู„ูƒ--
00:56
look at the pattern.
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ุฃูู†ุธุฑูˆุง ุฅู„ู‰ ุงู„ู†ู…ุท.
00:57
They're almost identical to real life.
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ุฅู†ู‡ู… ูŠุชุทุงุจู‚ูˆู† ุชู‚ุฑูŠุจุงู‹ ู…ุน ุงู„ุญูŠุงุฉ ุงู„ุญู‚ูŠู‚ูŠุฉ.
01:01
A very striking learning experience for a twenty-year-old.
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ุฎุจุฑุฉูŒ ุฏุฑุงุณูŠุฉูŒ ู„ุงูุชุฉู ุฌุฏุงู‹ ุจุงู„ู†ุณุจุฉ ู„ุทุงู„ุจู ุจุงู„ุนุดุฑูŠู†
01:07
Life is a learning program.
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ุงู„ุญูŠุงุฉ ุจุฑู†ุงู…ุฌ ุชุนู„ูŠู…ูŠ.
01:12
When you look at all of this wonderful world,
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ุนู†ุฏู…ุง ุชู†ุธุฑ ุฅู„ู‰ ูƒู„ ู‡ุฐุง ุงู„ุนุงู„ูŽู… ุงู„ุฑุงุฆุนุŒ
01:15
every species has its own learning program.
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ูƒู„ ูƒุงุฆู†ู ุญูŠู ู„ู‡ ุจุฑู†ุงู…ุฌูŒ ุชุนู„ูŠู…ูŠูŒ ุฎุงุตูŒ ุจู‡.
01:19
The learning program is genome,
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ุงู„ุจุฑู†ุงู…ุฌ ุงู„ุชุนู„ูŠู…ูŠ ู‡ูˆ โ€˜ุฌูŠู†ูˆู…โ€˜ุŒ
01:22
and the code of that program is DNA.
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ูˆุงู„ุฑู…ุฒ ู„ู‡ุฐุง ุงู„ุจุฑู†ุงู…ุฌ ู‡ูˆ ุงู„ุญู…ุถ ุงู„ู†ูˆูˆูŠุŒ DNA.
01:26
The different genomes of each species represent different survival strategies.
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ุงู„ุฌูŠู†ูˆู… ุงู„ู…ุฎุชู„ู ู„ุฃูŠ ูƒุงุฆู†ู ุญูŠู ูŠูู…ุซูู„ ุงุณุชุฑุงุชูŠุฌูŠุฉ ุจู‚ุงุกู ู…ุฎุชู„ูุฉ.
01:33
They represent hundreds of millions of years of evolution.
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ุฅู†ูŽู‡ุง ุชูู…ุซูู„ ู…ุฆุงุช ู…ู„ุงูŠูŠู† ุงู„ุณู†ูŠู† ู…ู† ุงู„ุชุทูˆุฑ.
01:38
The interaction between every species' ancestor
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ุงู„ุชูุงุนู„ ุจูŠู† ูƒู„ ุฃุณู„ุงู ุงู„ูƒุงุฆู†ุงุช
01:42
and the environment.
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ูˆุงู„ุจูŠุฆุฉ.
01:45
I was really fascinated about the world,
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ูƒู†ุช ุญู‚ุงู‹ ู…ู†ุจู‡ุฑุงู‹ ุจู‡ุฐุง ุงู„ุนุงู„ู…ุŒ
01:48
about the DNA,
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ุจุงู„ุญู…ุถ ุงู„ู†ูˆูˆูŠ DNAุŒ
01:49
about, you know, the language of life,
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ู‡ุฐู‡ุŒ ูƒู…ุง ุชุนุฑููˆู†ุŒ ู„ุบุฉ ุงู„ุญูŠุงุฉุŒ
01:52
the program of learning.
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ุงู„ุจุฑู†ุงู…ุฌ ุงู„ุชุนู„ูŠู…ูŠ.
01:54
So I decided to co-found the institute to read them.
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ู„ุฐู„ูƒุŒ ู‚ุฑุฑุช ุฃู† ุฃุคุณุณ ุงู„ู…ุนู‡ุฏ ุงู„ุฐูŠ ูŠู‚ุฑุฃู‡.
01:59
I read many of them.
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ุฃู†ุง ุฃู‚ุฑุฃ ุงู„ูƒุซูŠุฑ ู…ู†ู‡ู….
02:01
We probably read more than half of the prior animal genomes in the world.
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ุฑุจู…ุง ู†ู‚ุฑุฃ ุฃูƒุซุฑ ู…ู† ู†ุตู ุงู„ุฌูŠู†ูˆู… ู„ู„ุญูŠูˆุงู†ุงุช ุงู„ุฃูˆู„ู‰ ููŠ ุงู„ุนุงู„ู….
02:06
I mean, up to date.
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ุฃู‚ุตุฏุŒ ุญุชู‰ ูŠูˆู…ู†ุง ู‡ุฐุง.
02:09
We did learn a lot.
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ุชุนู„ู…ู†ุง ุงู„ูƒุซูŠุฑ.
02:11
We did sequence, also, one species many, many times ...
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ู‚ู…ู†ุง ุจุงู„ุชุณู„ุณู„ ูƒุฐู„ูƒุŒ ู„ูƒุงุฆู†ู ูˆุงุญุฏุŒ ู„ู…ุฑูŽุงุชู ุนุฏูŠุฏุฉ...
02:15
human genome.
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ุฌูŠู†ูˆู… ุงู„ุฅู†ุณุงู†.
02:16
We sequenced the first Asian.
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ุณู„ุณู„ู†ุง ุฃูˆู„ ุขุณูŠูˆูŠ.
02:17
I sequenced it myself many, many times,
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ุฃู†ุฌุฒุช ุงู„ุชุณู„ุณู„ ู„ู†ูุณูŠ ู…ุฑุงุชู ูˆู…ุฑุงุชู ุนุฏูŠุฏุฉุŒ
02:20
just to take advantage of that platform.
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ูู‚ุท ู„ู†ุณุชููŠุฏ ู…ู† ู‡ุฐู‡ ุงู„ู…ู†ุตุฉุŒ
02:24
Look at all those repeating base pairs:
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ุฃู†ุธุฑูˆุง ุฅู„ู‰ ู‡ุฐู‡ ุงู„ุฃุฒูˆุงุฌ ุงู„ู…ุชูƒุฑุฑุฉ:
02:27
ATCG.
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ATCG.
02:29
You don't understand anything there.
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ู„ุง ุชูู‡ู…ูˆู† ุดูŠุฆุง ู‡ู†ุงูƒ.
02:31
But look at that one base pair.
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ูˆู„ูƒู† ุงู†ุธุฑูˆุง ุฅู„ู‰ ุฐุงูƒ ุงู„ุฒูˆุฌ ุงู„ุฃุณุงุณูŠ
02:32
Those five letters, the AGGAA.
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ู‡ุฐู‡ ุงู„ุญุฑูˆู ุงู„ุฎู…ุณุฉ AGGAA.
02:35
These five SNPs represent a very specific haplotype
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ู‡ุฐู‡ ุงู„ุฎู…ุณุฉ SNP ุชู…ุซู„ ู…ุฌู…ูˆุนุฉ ุฌูŠู†ุงุชู ู…ุญุฏุฏุฉู ุฌุฏุงู‹
02:39
in the Tibetan population
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ู…ู† ุณูƒุงู† ุงู„ุชูŠุจุช
02:41
around the gene called EPAS1.
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ุญูˆู„ ุฌูŠู† ูŠุฏุนู‰ EPAS1.
02:43
That gene has been proved --
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ุฐู„ูƒ ุงู„ุฌูŠู† ุชู… ุฅุซุจุงุชู‡.
02:44
it's highly selective --
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ุงู†ูŽู‡ ุงู†ุชู‚ุงุฆูŠ ุฌุฏุงู‹.
02:46
it's the most significant signature of positive selection of Tibetans
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ุฅู†ูŽู‡ ุฃูƒุซุฑ ุนู„ุงู…ุฉ ูˆุถูˆุญุงู‹ ู„ู„ุงู†ุชู‚ุงุก ุงู„ุฅูŠุฌุงุจูŠ ู„ุฃุจู†ุงุก ุงู„ุชูŠุจุช
02:50
for the higher altitude adaptation.
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ู„ู„ุชุฃู‚ู„ู… ู…ุน ุงู„ู…ู†ุงุทู‚ ุงู„ู…ุฑุชูุนุฉ.
02:52
You know what?
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ุฃุชุนู„ู…ูˆู† ุดูŠุฆุงู‹ุŸ
02:54
These five SNPs were the result of integration of Denisovans,
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ู‡ุฐู‡ ุงู„ุฎู…ุณ SNP ูƒุงู†ุช ู†ุชูŠุฌุฉ ุชูƒุงู…ู„ ู„ู„ุฅู†ุณุงู† ุงู„ู‚ุฏูŠู…ุŒ
02:59
or Denisovan-like individuals into humans.
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ุฃูˆ ุฃูุฑุงุฏุงู‹ ุดุจูŠู‡ุฉู ุจุงู„ุฅู†ุณุงู† ุงู„ู‚ุฏูŠู…ุŒ ุฅู„ู‰ ุฅู†ุณุงู†
03:04
This is the reason why we need to read those genomes.
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ู‡ุฐุง ู‡ูˆ ุงู„ุณุจุจ ู„ู…ุงุฐุง ุนู„ูŠู†ุง ุฃู† ู†ู‚ุฑุฃ ุงู„ุฌูŠู†ูˆู….
03:06
To understand history,
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ู„ู†ูู‡ู… ุงู„ุชุงุฑูŠุฎ.
03:08
to understand what kind of learning process
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ู„ู†ูู‡ู… ู…ุง ู‡ูˆ ุงู„ู†ู‡ุฌ ุงู„ุชุนู„ูŠู…ูŠ
03:12
the genome has been through for the millions of years.
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ุงู„ุฐูŠ ู…ุฑูŽุช ุจู‡ ุงู„ุฌูŠู†ูˆู…ุงุช ู„ู…ู„ุงูŠูŠู† ุงู„ุณู†ูŠู†.
03:17
By reading a genome, it can give you a lot of information --
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ู‚ุฑุงุกุฉ ุงู„ุฌูŠู†ูˆู…ุŒ ูŠู…ูƒู† ุฃู† ุชุฒูˆูุฏู†ุง ุจุงู„ูƒุซูŠุฑ ู…ู† ุงู„ู…ุนู„ูˆู…ุงุช ..
03:20
tells you the bugs in the genome --
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ุชุฎุจุฑูƒ ุจุงู„ุนูŠูˆุจ ููŠ ุงู„ุฌูŠู†ูˆู… ..
03:21
I mean, birth defects, monogenetic disorders.
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ุฃุนู†ูŠ ุงู„ุนูŠูˆุจ ุงู„ุชูŠ ุชุฃุชูŠ ุจุงู„ูˆู„ุงุฏุฉุŒ ุนูŠุจุงู‹ ูŠุตูŠุจ ุฌูŠู†ุงู‹ ุฃุญุงุฏูŠุงู‹.
03:25
Reading a drop of blood
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ุจู‚ุฑุงุกุฉ ู†ู‚ุทุฉ ุฏู…
03:26
could tell you why you got a fever,
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ูŠู…ูƒู†ู‡ุง ุฃู† ุชุฎุจุฑูƒ ู„ู… ุฃูุตุจุช ุจุงู„ุญู…ูŽู‰.
03:28
or it tells you which medicine and dosage needs to be used
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ุฃูˆ ุชุฎุจุฑูƒ ู…ุงู‡ูˆ ุงู„ุฏูˆุงุก ูˆูƒู… ู‡ูŠ ุงู„ุฌุฑุนุฉ ุงู„ู„ุงุฒู…ุฉ
03:31
when you're sick, especially for cancer.
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ุนู†ุฏู…ุง ุชู…ุฑุถุŒ ูˆุฎุงุตุฉู‹ ุจุงู„ุณุฑุทุงู†.
03:35
A lot of things could be studied, but look at that:
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ูƒุซูŠุฑ ู…ู† ุงู„ุฃู…ูˆุฑ ูŠู…ูƒู† ุฏุฑุงุณุชู‡ุงุŒ ูˆู„ูƒู† ุงู†ุธุฑูˆุง ู„ู‡ุฐุง:
03:38
30 years ago, we were still poor in China.
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ู…ู†ุฐ 30 ุนุงู…ุงู‹ุŒ ูƒู†ุง ู„ุง ู†ุฒุงู„ ูู‚ุฑุงุก ุจุงู„ุตูŠู†.
03:42
Only .67 percent of the Chinese adult population had diabetes.
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ูู‚ุท 0.67 ุจุงู„ู…ุฆุฉ ู…ู† ุณูƒุงู† ุงู„ุตูŠู† ุงู„ุจุงู„ุบูŠู† ูƒุงู†ูˆุง ูŠุนุงู†ูˆู† ู…ู† ุงู„ุณูƒุฑูŠ.
03:47
Look at now: 11 percent.
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ุงู„ุขู†: 11 ุจุงู„ู…ุฆุฉ.
03:49
Genetics cannot change over 30 years --
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ุงู„ุฌูŠู†ุงุช ู„ุง ูŠู…ูƒู† ุฃู† ุชุชุบูŠุฑ ุฎู„ุงู„ 30 ุนุงู…ุงู‹ ..
03:52
only one generation.
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ูู‚ุท ุฌูŠู„ ูˆุงุญุฏ.
03:54
It must be something different.
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ู„ุง ุจุฏูŽ ู…ู† ุฃู…ุฑู ุขุฎุฑ.
03:56
Diet?
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ู†ูˆุน ุงู„ุบุฐุงุกุŸ
03:57
The environment?
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ุงู„ุจูŠุฆุฉุŸ
03:59
Lifestyle?
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ุทุฑูŠู‚ุฉ ุงู„ุญูŠุงุฉุŸ
04:01
Even identical twins could develop totally differently.
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ุญุชู‰ ุงู„ุชูˆุงุฆู… ุงู„ู…ุชุทุงุจู‚ูŠู† ูŠู…ูƒู† ุฃู† ูŠู†ู…ูˆุง ุจุดูƒู„ู ู…ุฎุชู„ูู ูƒู„ูŠุงู‹
04:06
It could be one becomes very obese, the other is not.
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ูŠู…ูƒู† ุฃู† ูŠุนุงู†ูŠ ุฃุญุฏู‡ู…ุง ู…ู† ุงู„ุณู…ู†ุฉ ุงู„ุฒุงุฆุฏุฉุŒ ุฃู…ูŽุง ุงู„ุซุงู†ูŠ ูู„ุง.
04:10
One develops a cancer and the other does not.
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ุฃู† ูŠุชุทูˆุฑ ุณุฑุทุงู†ุงู‹ ุนู†ุฏ ุฃุญุฏู‡ู…ุง ุฏูˆู† ุงู„ุขุฎุฑ.
04:13
Not mentioning living in a very stressed environment.
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ูƒู„ ู‡ุฐุง ูˆู„ู… ู†ุฐูƒุฑ ุงู„ุนูŠุด ุจุจูŠุฆุฉู ู…ุชูˆุชูุฑุฉ.
04:19
I moved to Shenzhen 10 years ago ...
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ุงู†ุชู‚ู„ุช ุฅู„ู‰ (ุดู†ุฒู†) ู…ู†ุฐ ุนุดุฑุฉ ุณู†ูˆุงุช ...
04:22
for some reason, people may know.
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ู„ุณุจุจู ู…ุนูŠู†ุŒ ู‚ุฏ ูŠุนู„ู…ู‡ ุงู„ู†ุงุณ.
04:25
If the gene's under stress,
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ุฅุฐุง ุชุนุฑู‹ุถ ุงู„ุฌูŠู† ู„ู„ุชูˆุชุฑุŒ
04:27
it behaves totally differently.
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ูŠุชุตุฑูŽู ุจุดูƒู„ู ู…ุฎุชู„ูู ุชู…ุงู…ุงู‹.
04:30
Life is a journey.
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ุงู„ุญูŠุฉ ุฑุญู„ุฉ.
04:32
A gene is just a starting point,
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ุงู„ุฌูŠู† ู‡ูˆ ู…ุฌุฑุฏ ู†ู‚ุทุฉ ุจุฏุงูŠุฉุŒ
04:35
not the end.
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ูˆู„ูŠุณ ุงู„ู†ู‡ุงูŠุฉ.
04:37
You have this statistical risk of certain diseases when you are born.
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ู„ุฏูŠูƒู… ู‡ุฐู‡ ุงู„ู…ุฎุงุทุฑ ุงู„ุฅุญุตุงุฆูŠุฉ ู„ุฃู…ุฑุงุถู ู…ุนูŠู†ุฉู ู…ู†ุฐ ูˆู„ุงุฏุชูŠ.
04:42
But every day you make different choices,
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ูˆู„ูƒู†ูƒู… ุชุชุฎุฐูˆู† ุฎูŠุงุฑุงุชู ู…ุฎุชู„ูุฉู ููŠ ูƒู„ ูŠูˆู…ุŒ
04:45
and those choices will increase or decrease the risk of certain diseases.
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ูˆู‡ุฐู‡ ุงู„ุฎูŠุงุฑุงุช ุชุฒูŠุฏ ุฃูˆ ุชู†ู‚ุต ู…ุฎุงุทุฑ ุฃู…ุฑุงุถู ู…ุนูŠู†ุฉ.
04:51
But do you know where you are on the curve?
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ูˆู„ูƒู† ู‡ู„ ุชุนุฑู ู…ูˆู‚ุนูƒ ุนู„ู‰ ุงู„ู…ู†ุญู†ู‰ุŸ
04:54
What's the past curve look like?
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ูˆูƒูŠู ูƒุงู† ูŠุจุฏูˆ ุงู„ู…ู†ุญู†ู‰ ุงู„ุณุงุจู‚ุŸ
04:56
What kind of decisions are you facing every day?
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ูˆู…ุง ู†ูˆุน ุงู„ู‚ุฑุงุฑุงุช ุงู„ุชูŠ ุชูˆุงุฌู‡ู‡ุง ูƒู„ ูŠูˆู…ุŸ
04:59
And what kind of decision is the right one
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ูˆู…ุง ู†ูˆุน ุงู„ู‚ุฑุงุฑ ุงู„ุตุงุฆุจ
05:02
to make your own right curve over your life journey?
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ู„ุชุตู†ุน ุงู„ู…ู†ุญูŽู†ู‰ ุงู„ุตุญูŠุญ ุงู„ุฎุงุต ุจูƒ ุฎู„ุงู„ ุฑุญู„ุฉ ุญูŠุงุชูƒุŸ
05:07
What's that?
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ู…ุง ู‡ุฐุงุŸ
05:09
The only thing you cannot change,
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ุงู„ุดูŠุก ุงู„ูˆุญูŠุฏ ุงู„ุฐูŠ ู„ุง ูŠู…ูƒู†ูƒ ุชุบูŠูŠุฑู‡ุŒ
05:11
you cannot reverse back,
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ู„ุง ุชุณุชุทูŠุน ุฅุนุงุฏุชู‡ ู„ู„ูˆุฑุงุกุŒ
05:13
is time.
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ู‡ูˆ ุงู„ุฒู…ู†.
05:14
Probably not yet; maybe in the future.
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ุฑุจู…ุง ู„ูŠุณ ุจุนุฏุŒ ุฑุจู…ุง ููŠ ุงู„ู…ุณุชู‚ุจู„.
05:16
(Laughter)
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(ุถุญูƒ)
05:17
Well, you cannot change the decision you've made,
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ุญุณู†ุงู‹ุŒ ู„ุง ูŠู…ูƒู† ุชุบูŠูŠุฑ ู‚ุฑุงุฑู ุณุจู‚ ูˆุงุชุฎุฐุชู‡ุŒ
05:20
but can we do something there?
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ูˆู„ูƒู† ู‡ู„ ูŠู…ูƒู† ุนู…ู„ ุดูŠุกู ู…ุงุŸ
05:22
Can we actually try to run multiple options on me,
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ู‡ู„ ู†ุณุชุทูŠุน ุฃู† ู†ุฌุฑูŠ ุนุฏุฉ ุฅุฎุชูŠุงุฑุงุชู ุนู„ูŠ ุฃู†ุงุŒ
05:27
and try to predict right on the consequence,
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ูˆุฃู† ู†ุญุงูˆู„ ุงู† ู†ุชู†ุจูŽุฃ ุจุงู„ู†ุชุงุฆุฌุŒ
05:31
and be able to make the right choice?
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ูˆุฃู† ู†ูƒูˆู† ู‚ุงุฏุฑูŠู† ุนู„ู‰ ุงุชุฎุงุฐ ุงู„ุฎูŠุงุฑ ุงู„ุตุงุฆุจุŸ
05:33
After all,
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ุจุงู„ู…ุญุตู‘ูู„ุฉุŒ
05:35
we are our choices.
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ู†ุญู† ู†ุชูŠุฌุฉ ุงุฎุชูŠุงุฑุงุชู†ุง.
05:38
These lady beetles came to me afterwards.
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ู‡ุฐู‡ ุงู„ุฎู†ูุณุงุก ุฌุงุกุช ู„ูŠ ุจุนุฏ ุฐู„ูƒ.
05:41
25 years ago, I made the digital lady beetles
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ู…ู†ุฐ 25 ุณู†ุฉุŒ ุตู†ุนุช ุงู„ุฎู†ูุณุงุก ุงู„ุฑู‚ู…ูŠุฉ.
05:44
to try to simulate real lady beetles.
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ู„ู…ุญุงูˆู„ุฉ ู…ุญุงูƒุงุฉ ุฎู†ูุณุงุก ุญู‚ูŠู‚ูŠุฉ.
05:47
Can I make a digital me ...
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ู‡ู„ ูŠู…ูƒู† ุตู†ุนูŠ โ€˜ุฃู†ุงโ€˜ ุฑู‚ู…ูŠุงู‹ ...
05:49
to simulate me?
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ูˆู…ุญุงูƒุงุชูŠุŸ
05:51
I understand the neural network could become
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ุฃู†ุง ุฃุชูู‡ูŽู… ุฃู†ูŽ ุงู„ุดุจูƒุฉ ุงู„ุนุตุจูŠุฉ ุชุตุจุญ
05:54
much more sophisticated and complicated there.
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ุฃูƒุซุฑ ุชุนู‚ูŠุฏุงู‹ ูˆุชุดุงุจูƒุงู‹ ู‡ู†ุงูƒ.
05:57
Can I make that one,
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ู‡ู„ ูŠู…ูƒู† ุฃู† ุฃุตู†ุน ู‡ุฐู‡ุŒ
05:59
and try to run multiple options on that digital me --
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ูˆุฃุญุงูˆู„ ุฃู† ุฃุฌุฑูŠ ุฎูŠุงุฑุงุชู ู…ุชุนุฏุฏุฉู ุนู„ู‰ โ€˜ุฃู†ุงโ€˜ ุงู„ุฑู‚ู…ูŠ ..
06:02
to compute that?
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ูˆุฃู† ุฃุญุณุจ ูƒู„ ุฐู„ูƒุŸ
06:04
Then I could live in different universes,
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ูˆุนู†ุฏู‡ุง ูŠู…ูƒู†ู†ูŠ ุฃู† ุฃุนูŠุด ููŠ ุนูˆุงู„ู… ุขุฎุฑู‰ุŒ
06:07
in parallel, at the same time.
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ู…ูˆุงุฒูŠุฉู‹ุŒ ูˆููŠ ุฐุงุช ุงู„ูˆู‚ุช.
06:10
Then I would choose whatever is good for me.
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ูˆุนู†ุฏู‡ุง ุฃุฎุชุงุฑ ุงู„ุฌูŠุฏ ุจุงู„ู†ุณุจุฉ ู„ูŠ.
06:14
I probably have the most comprehensive digital me on the planet.
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ุฑุจู…ุง ุฃู…ู„ูƒ ุงู„ุดุฎุตูŠุฉ ุงู„ุฑู‚ู…ูŠุฉ ุงู„ุฃูƒุซุฑ ุดู…ูˆู„ุงู‹ ุนู„ู‰ ู‡ุฐุง ุงู„ูƒูˆูƒุจ.
06:17
I've spent a lot of dollars on me, on myself.
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ุฃู†ูู‚ุช ุงู„ูƒุซูŠุฑ ู…ู† ุงู„ุฏูˆู„ุงุฑุงุช ุนู„ู‰ โ€˜ุฃู†ุงโ€˜ุŒ ุนู„ู‰ ุฐุงุชูŠ.
06:21
And the digital me told me I have a genetic risk of gout
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ูˆุดุฎุตูŠุชูŠ ุงู„ุฑู‚ู…ูŠุฉ ุฃุฎุจุฑุชู†ูŠ ุจูˆุฌูˆุฏ ุฎุทุฑ ุฌูŠู†ูŠู ุจุงู„ู…ูุงุตู„
06:27
by all of those things there.
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ุจูƒู„ ุชู„ูƒ ุงู„ุฃุดูŠุงุก ู‡ู†ุงูƒ.
06:29
You need different technology to do that.
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ุชุญุชุงุฌ ู„ุชู‚ู†ูŠุฉ ู…ุฎุชู„ูุฉ ู„ู„ูˆุตูˆู„ ู„ุฐู„ูƒุŒ
06:31
You need the proteins, genes,
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ุชุญุชุงุฌ ุงู„ุจุฑูˆุชูŠู†ุŒ ุงู„ุฌูŠู†ุงุชุŒ
06:32
you need metabolized antibodies,
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ุชุญุชุงุฌ ู„ุฅุฌุณุงู…ู ู…ุถุงุฏู‘ุฉู ู‚ุงุจู„ุฉู‹ ู„ู„ุญูŠุงุฉุŒ
06:35
you need to screen all your body
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ุชุญุชุงุฌ ุฅู„ู‰ ุบุฑุจู„ุฉ ูƒู„ ุฌุณู…ูƒ
06:37
about the bacterias and viruses covering you, or in you.
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ู…ู† ุงู„ุจูƒุชูŠุฑูŠุง ูˆุงู„ููŠุฑูˆุณุงุช ุงู„ุชูŠ ุชุบุทูŠูƒุŒ ุฃูˆ ููŠ ุฏุงุฎู„ูƒ.
06:41
You need to have all the smart devices there --
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ุชุญุชุงุฌ ุฅู„ู‰ ูƒู„ ุงู„ุฃุฌู‡ุฒุฉ ุงู„ุฐูƒูŠุฉ ู‡ู†ุงูƒ ..
06:44
smart cars, smart house, smart tables,
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ุณูŠุงุฑุงุชู ุฐูƒูŠุฉุŒ ุจูŠุชู ุฐูƒูŠุŒ ู…ู†ุถุฏุฉู ุฐูƒูŠุฉุŒ
06:47
smart watch, smart phone to track all of your activities there.
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ุณุงุนุฉู ุฐูƒูŠุฉุŒ ู‡ุงุชูู ุฐูƒูŠ ู„ุชุชุจุน ูƒู„ ู†ุดุงุทุงุชูƒ ู‡ู†ุงูƒ.
06:51
The environment is important --
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ุงู„ุจูŠุฆุฉ ู…ู‡ู…ุฉ...
06:52
everything's important --
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ูƒู„ ุดูŠุกู ู…ู‡ู…...
06:53
and don't forget the smart toilet.
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ูˆู„ุง ุชู†ุณู‰ ุงู„ู…ุฑุญุงุถ ุงู„ุฐูƒูŠ.
06:55
(Laughter)
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(ุถุญูƒ)
06:56
It's such a waste, right?
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ูŠุง ู„ู‡ ู…ู† ู‡ุฏุฑุŒ ุฃู„ูŠุณ ูƒุฐู„ูƒุŸ
06:58
Every day, so much invaluable information just has been flushed into the water.
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ูƒู„ ูŠูˆู…ุŒ ู…ุนู„ูˆู…ุงุชู ู„ุง ุชู‚ุฏุฑ ุจุซู…ู† ูŠุชู… ุงู„ุชุฎู„ุต ู…ู†ู‡ุง ุจุงู„ู…ุงุก
07:04
And you need them.
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ูˆุฃู†ุช ุชุญุชุงุฌ ู„ู‡ุฐู‡ ุงู„ู…ุนู„ูˆู…ุงุช.
07:05
You need to measure all of them.
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ุชุฑูŠุฏ ุชุญู„ูŠู„ู‡ุง ุฌู…ูŠุนู‡ุง.
07:07
You need to be able to measure everything around you
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ุชุฑูŠุฏ ุฃู† ุชุชู…ูƒู† ู…ู† ุชุญู„ูŠู„ ูƒู„ ู…ุง ูŠุฏูˆุฑ ุญูˆู„ูƒ
07:10
and compute them.
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ูˆุงู† ุชุญุณุจู‡ู….
07:11
And the digital me told me I have a genetic defect.
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ูˆุดุฎุตูŠุชูŠ ุงู„ุฑู‚ู…ูŠุฉ ุฃุฎุจุฑุชู†ูŠ ุฃู† ู„ุฏูŠ ุนูŠุจุงู‹ ุฎูŠู†ูŠุงู‹
07:16
I have a very high risk of gout.
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ู„ุฏูŠ ุฎุทุฑ ุนุงู„ู ู„ู„ุฅุตุงุจุฉ ุจุงู„ู†ู‚ุฑุณ.
07:19
I don't feel anything now,
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ู„ุง ุฃุดุนุฑ ุจุดูŠุกู ุงู„ุขู†ุŒ
07:21
I'm still healthy.
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ู…ุง ุฒู„ุช ุจุตุญุฉู ุฌูŠุฏุฉ.
07:22
But look at my uric acid level.
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ูˆู„ูƒู† ุฃู†ุธุฑ ุฅู„ู‰ ู…ุณุชูˆู‰ ุญู…ุถ ุงู„ูŠูˆุฑูŠุง.
07:24
It's double the normal range.
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ุฃู†ู‡ ุถุนููŠู‘ ุงู„ู…ุฏู‰ ุงู„ุทุจูŠุนูŠ.
07:26
And the digital me searched all the medicine books,
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ูˆุดุฎุตูŠุชูŠ ุงู„ุฑู‚ู…ูŠุฉ ุจุญุซุช ููŠ ูƒู„ ูƒุชุจ ุงู„ุทุจุŒ
07:29
and it tells me, "OK, you could drink burdock tea" --
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ูˆุฃุฎุจุฑูŽู†ูŠุŒ โ€˜ุญุณู†ุงู‹ุŒ ูŠู…ูƒู†ูƒ ุดุฑุจ ุดุงูŠ ุงู„ุจุฑุฏูƒโ€˜..
07:33
I cannot even pronounce it right --
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ุญุชู‰ ุฃู†ูŠ ู„ุง ุฃุณุชุทูŠุน ู„ูุธู‡ ุฌูŠุฏุงู‹..
07:35
(Laughter)
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(ุถุญูƒ)
07:36
That is from old Chinese wisdom.
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ู‡ุฐุง ู…ู† ุญูƒู…ุฉู ุตูŠู†ูŠุฉู ู‚ุฏูŠู…ุฉ.
07:38
And I drank that tea for three months.
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ูˆู‚ู…ุช ุจุดุฑุจ ู‡ุฐุง ุงู„ุดุงูŠ ู„ุซู„ุงุซุฉ ุฃุดู‡ุฑ.
07:41
My uric acid has now gone back to normal.
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ู…ุณุชูˆู‰ ุงู„ูŠูˆุฑูŠุง ุนุงุฏ ุงู„ุขู† ู„ูˆุถุนู‡ ุงู„ุทุจูŠุนูŠ.
07:44
I mean, it worked for me.
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ุฃู‚ุตุฏุŒ ู†ูุนุช ุจุงู„ู†ุณุจุฉ ู„ูŠ.
07:46
All those thousands of years of wisdom worked for me.
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ุญูƒู…ุฉ ูƒู„ ู‡ุฐู‡ ุงู„ุขู„ุงู ู…ู† ุงู„ุณู†ูŠู† ู†ูุนุช ู…ุนูŠ.
07:49
I was lucky.
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ูƒู†ุช ู…ุญุธูˆุธุงู‹.
07:50
But I'm probably not lucky for you.
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ูˆู„ูƒู†ูŠ ู‚ุฏ ู„ุง ุฃูƒูˆู† ู…ุญุธูˆุธุงู‹ ู„ูƒู….
07:55
All of this existing knowledge in the world
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ูƒู„ ู‡ุฐู‡ ุงู„ู…ุนุฑูุฉ ุงู„ู…ุซูŠุฑุฉ ููŠ ุงู„ุนุงู„ู…
07:57
cannot possibly be efficient enough or personalized enough for yourself.
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ู‚ุฏ ู„ุง ุชูƒูˆู† ูุนู‘ุงู„ุฉู‹ ุจู…ุง ูŠูƒููŠ ุฃูˆ ู…ุฎุตู‘ุตุฉู‹ ุจู…ุง ูŠูƒููŠ ู„ูƒ ุฃู†ุช.
08:03
The only way to make that digital me work ...
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ุงู„ุทุฑูŠู‚ ุงู„ูˆุญูŠุฏ ู„ุฌุนู„ ู‡ุฐุง ุงู„ู€ โ€˜ุฃู†ุงโ€˜ ุงู„ุฑู‚ู…ูŠ ูŠุนู…ู„ ..
08:07
is to learn from yourself.
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ู‡ูˆ ุฃู† ู†ุชุนู„ู‘ู… ู…ู† ุฐุงุชูƒ ุฃู†ุชุŒ
08:10
You have to ask a lot of questions about yourself:
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ุนู„ูŠูƒ ุฃู† ุชุณุฃู„ ุงู„ูƒุซูŠุฑ ุนู† ุฐุงุชูƒ:
08:13
"What if?" --
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โ€˜ู…ุงุฐุง ู„ูˆุŸโ€˜ ..
08:15
I'm being jet-lagged now here.
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ุฃู†ุง ุฃุนุงู†ูŠ ู…ู† ุฅุฎุชู„ุงู ุงู„ุชูˆู‚ูŠุช.
08:16
You don't probably see it, but I do.
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ุฑุจู…ุง ู„ุง ุชู„ุงุญุธูˆู†ุŒ ูˆู„ูƒู†ูŠ ูƒุฐู„ูƒ.
08:19
What if I eat less?
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ู…ุงุฐุง ู„ูˆ ุฃูƒู„ุชู ุฃู‚ู„ุŸ
08:21
When I took metformin, supposedly to live longer?
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ู…ุชู‰ ุชู†ุงูˆู„ุชู "ู…ูŠุชููˆุฑู…ูŠู†"ุŒ ุนู„ู‰ ุฃุณุงุณ ุฃู† ุฃุนูŠุด ุฃูƒุซุฑุŸ
08:25
What if I climb Mt. Everest?
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ู…ุงุฐุง ู„ูˆ ุชุณู„ู‘ู‚ุชู ุฌุจู„ ุฅูŠูุฑุณุชุŸ
08:26
It's not that easy.
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ู‡ุฐุง ู„ูŠุณ ุณู‡ู„ุงู‹.
08:28
Or run a marathon?
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ุฃูˆ ุฃู† ุฃุชุณุงุจู‚ ุจู…ุงุฑุงุซูˆู†ุŸ
08:29
What if I drink a bottle of mao-tai,
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ู…ุงุฐุง ู„ูˆ ุดุฑุจุช ู‚ู†ูŠู†ุฉ ู…ู† ุดุฑุงุจ (ู…ูˆ-ุชุงูŠ)ุŒ
08:32
which is a Chinese liquor,
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ูˆู‡ูŠ ูƒุญูˆู„ ุตูŠู†ูŠุฉุŒ
08:33
and I get really drunk?
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ูˆุซู…ู„ุช ุชู…ุงู…ุงู‹ุŸ
08:34
I was doing a video rehearsal last time with the folks here,
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ูƒู†ุช ุฃู‚ูˆู… ุจููŠุฏูŠูˆ ุชุฌุฑูŠุจูŠ ุขุฎุฑ ู…ุฑู‘ุฉู ู„ูŠ ู…ุน ุงู„ุฑูุงู‚ ู‡ู†ุงุŒ
08:39
when I was drunk,
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ูƒู†ุชู ุซู…ู„ุงู‹ุŒ
08:40
and I totally delivered a different speech.
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ูˆุฃู„ู‚ูŠุชู ุฎุทุงุจุงู‹ ู…ุฎุชู„ูุงู‹ ุชู…ุงู…ุงู‹.
08:42
(Laughter)
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(ุถุญูƒ)
08:45
What if I work less, right?
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ู…ุงุฐุง ู„ูˆ ุนู…ู„ุช ุฃู‚ู„ุŸ
08:47
I have been less stressed, right?
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ุฃูƒูˆู† ุฃู‚ู„ ุชูˆุชุฑุงู‹ ุฃู„ูŠุณ ูƒุฐู„ูƒุŸ
08:49
So that probably never happened to me,
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ุฑุจู…ุง ู„ู… ูŠุญุตู„ ู‡ุฐุง ู„ูŠ ุฃุจุฏุงู‹ุŒ
08:51
I was really stressed every day,
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ูƒู†ุช ูŠูˆู…ูŠุงู‹ ู…ูุฌู‡ุฏุงู‹ ุญู‚ู‘ุงู‹.
08:53
but I hope I could be less stressed.
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ูˆู„ูƒู†ูŠ ุฃุชู…ู†ู‰ ุฃู† ุฃูƒูˆู† ุฃู‚ู„ ุชูˆุชุฑุงู‹.
08:56
These early studies told us,
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ุงู„ุฏุฑุงุณุงุช ุงู„ุฃูˆู„ู‰ ุฃุฎุจุฑุชู†ุงุŒ
08:58
even with the same banana,
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ุญุชูŠ ู…ุน ู†ูุณ ุงู„ู…ูˆุฒุฉุŒ
09:00
we have totally different glucose-level reactions
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ู†ุญุตู„ ุนู„ู‰ ุชูุงุนู„ุงุช ู„ู…ุณุชูˆู‰ ุงู„ุฌู„ูˆูƒูˆุฒ ู…ุบุงูŠุฑุฉู‹ ุชู…ุงู…ุงู
09:03
over different individuals.
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ุนู„ูŠ ุฃูุฑุงุฏุงู‹ ู…ุฎุชู„ููŠู†.
09:04
How about me?
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ู…ุงุฐุง ุนู†ู‘ูŠ ุฃู†ุงุŸ
09:06
What is the right breakfast for me?
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ู…ุง ู‡ูˆ ุงู„ูุทูˆุฑ ุงู„ู…ู†ุงุณุจ ู„ูŠุŸ
09:08
I need to do two weeks of controlled experiments,
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ุนู„ูŽูŠู‘ูŽ ุฃู† ุฃู‚ูˆู… ุจุฃุณุจูˆุนูŠู† ู…ู† ุงู„ุชุฌุงุฑุจ ุงู„ู…ู†ุถุจุทุฉุŒ
09:11
of testing all kinds of different food ingredients on me,
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ู„ูุญุต ูƒู„ ุฃู†ูˆุงุน ู…ูƒูˆู†ุงุช ุงู„ุบุฐุงุก ุงู„ู…ุฎุชู„ูุฉ ุนู„ูŽูŠู‘ุŒ
09:14
and check my body's reaction.
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ูˆุฃุฑุงู‚ุจ ุฑุฏุฉ ุงู„ูุนู„ ุนู„ู‰ ุฌุณู…ูŠ.
09:17
And I don't know the precise nutrition for me,
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ูˆุฃู†ุง ู„ุง ุฃุฏุฑูŠ ู…ุง ู‡ูˆ ุงู„ู†ุธุงู… ุงู„ุบุฐุงุฆูŠ ุงู„ู…ู†ุงุณุจ ู„ูŠ ุชุญุฏูŠุฏุงู‹ุŒ
09:20
for myself.
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ู„ูŠ ุฃู†ุง.
09:23
Then I wanted to search all the Chinese old wisdom
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ุซู… ุฃุฑุฏุช ุฃู† ุฃุจุญุซ ููŠ ูƒู„ ุงู„ุญูƒู…ุฉ ุงู„ุตูŠู†ูŠุฉ ุงู„ู‚ุฏูŠู…ุฉ
09:27
about how I can live longer, and healthier.
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ุนู† ูƒูŠููŠุฉ ุงู„ุนูŠุด ุฃุทูˆู„ุŒ ูˆุจุตุญุฉู ุฃูุถู„.
09:30
I did it.
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ูˆูุนู„ุชู‡ุง.
09:31
Some of them are really unachievable.
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ุจุนุถู‡ุง ู„ุง ูŠู…ูƒู† ุชุญุตูŠู„ู‡ุง.
09:34
I did this once last October,
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ูุนู„ุช ู‡ุฐุง ู…ุฑู‘ูŽุฉู‹ ููŠ ุฃูƒุชูˆุจุฑ ุงู„ู…ุงุถูŠุŒ
09:37
by not eating for seven days.
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ุจุงู† ู„ุง ุขูƒู„ ู„ุณุจุนุฉ ุฃูŠุงู…ู.
09:39
I did a fast for seven days with six partners of mine.
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ู‚ู…ุช ุจุงู„ุตูŠุงู… ู„ุณุจุนุฉ ุฃุจุงู…ู ู…ุน ุณุชุฉู ู…ู† ุดุฑูƒุงุฆูŠ.
09:44
Look at those people.
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ุฃู†ุธุฑูˆุง ุฅู„ู‰ ู‡ุคู„ุงุก ุงู„ู†ุงุณ.
09:45
One smile.
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ุจุณู…ู‡ ูˆุงุญุฏู‡.
09:47
You know why he smiled?
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ุฃุชุนู„ู…ูˆู† ู„ู…ุงุฐุง ุงุจุชุณู…ุŸ
09:48
He cheated.
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ู„ู‚ุฏ ุบุด.
09:49
(Laughter)
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(ุถุญูƒ)
09:50
He drank one cup of coffee at night,
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ุดุฑุจ ูƒูˆุจุงู‹ ู…ู† ุงู„ู‚ู‡ูˆุฉ ุฎู„ุงู„ ุงู„ู„ูŠู„,
09:53
and we caught it from the data.
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ูˆุถุจุทู†ุง ุฐู„ูƒ ู…ู† ุงู„ู…ุนุทูŠุงุช.
09:55
(Laughter)
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(ุถุญูƒ)
09:56
We measured everything from the data.
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ู‚ุณู†ุง ูƒู„ ุดูŠุกู ู…ู† ุงู„ู…ุนุทูŠุงุช.
09:58
We were able to track them,
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ูƒู†ุง ู‚ุงุฏุฑูŠู† ุนู„ู‰ ุชุชุจุนู‡ู…ุŒ
10:00
and we could really see --
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ูˆุชู…ูƒู†ู‘ุง ุญู‚ู‘ุงู‹ ุจุฃู† ู†ุฑู‰ ..
10:02
for example, my immune system,
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ู…ุซู„ุงู‹ุŒ ุฌู‡ุงุฒูŠ ุงู„ู…ู†ุงุนูŠุŒ
10:04
just to give you a little hint there.
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ูู‚ุท ู„ุงุนุทูŠูƒู… ููƒุฑุฉู ุตุบูŠุฑุฉู ู‡ู†ุงุŒ
10:06
My immune system changed dramatically over 24 hours there.
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ุฌู‡ุงุฒูŠ ุงู„ู…ู†ุงุนูŠ ุชุบูŠู‘ุฑ ุจุดูƒู„ู ุฌุฐุฑูŠู ุนู„ู‰ ู…ุฏู‰ 24 ุณุงุนุฉู ู‡ู†ุงูƒ.
10:11
And my antibody regulates my proteins
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ูˆุงู„ุฃุฌุณุงู… ุงู„ู…ุถุงุฏุฉ ู†ุธู‘ูŽู…ุช ุงู„ุจุฑูˆุชูŠู†
10:14
for that dramatic change.
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ู„ู‡ุฐุง ุงู„ุชุบูŠูŠุฑ ุงู„ุฌุฐุฑูŠ.
10:16
And everybody was doing that.
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ูˆูƒู„ ูˆุงุญุฏู ูุนู„ ู‡ุฐุง.
10:17
Even if we're essentially totally different at the very beginning.
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ุจุงู„ุฑุบู… ุงู†ู†ุง ูƒู†ุง ุฃุณุงุณุง ู…ุฎุชู„ููŠู† ุชู…ุงู…ุงู‹ ุนู†ุฏ ุงู„ุจุฏุงูŠุฉ.
10:21
And that probably will be an interesting treatment in the future
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ูˆุฑุจู…ุง ูŠูƒูˆู† ู‡ุฐุง ุนู„ุงุฌุงู‹ ู…ุดูˆู‘ูู‚ุงู‹ ุจุงู„ู…ุณุชู‚ุจู„
10:24
for cancer and things like that.
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ู„ู„ุณุฑุทุงู† ูˆู…ุง ูŠุดุงุจู‡ู‡.
10:25
It becomes very, very interesting.
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ุฃุตุจุญุช ู…ุดูˆู‘ูู‚ุฉู‹ ุฌุฏุงู‹.
10:28
But something you probably don't want to try,
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ูˆู„ูƒู† ุดูŠุฆุงู‹ ู…ุง ู‚ุฏ ู„ุง ุชุฑุบุจ ุจุชุฌุฑุจุชู‡ุŒ
10:30
like drinking fecal water from a healthier individual,
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ู…ุซู„ ุดุฑุจ ู…ุงุก ุจุฑุงุฒู ู…ู† ุดุฎุตู ู…ุนุงูู‰ุŒ
10:34
which will make you feel healthier.
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ูˆุงู„ุฐูŠ ุณูŠุฌุนู„ูƒ ุจุตุญุฉู ุฃูุถู„.
10:36
This is from old Chinese wisdom.
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ู‡ุฐุง ู…ู† ุญูƒู…ุฉู ุตูŠู†ูŠุฉู ู‚ุฏูŠู…ุฉุŒ
10:37
Look at that, right?
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ุฃู†ุธุฑูˆุง ุฅู„ู‰ ู‡ุฐุงุŒ ุตุญุŸ
10:39
Like 1,700 years ago,
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ู…ุซู„ ู‚ุจู„ 1700 ุณู†ุฉุŒ
10:41
it's already there, in the book.
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ุฅู†ู‡ ู…ูˆุฌูˆุฏูŒ ู‡ู†ุงูƒุŒ ุจุงู„ูƒุชุงุจ.
10:44
But I still hate the smell.
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ูˆู„ูƒู†ูŠ ู…ุง ุฒู„ุช ุฃูƒุฑู‡ ุงู„ุฑุงุฆุญุฉ.
10:46
(Laughter)
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(ุถุญูƒ)
10:47
I want to find out the true way to do it,
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ุฃุฑูŠุฏ ุฃู† ุฃุฌุฏ ุงู„ุทุฑูŠู‚ุฉ ุงู„ุตุญูŠุญุฉ ู„ูุนู„ู‡ุงุŒ
10:49
maybe find a combination of cocktails of bacterias and drink it,
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ุฑุจู…ุง ู„ุฃุฌุฏ ุชุฑูƒูŠุจุฉ ู…ุฒูŠุฌู ู…ู† ุงู„ุจูƒุชูŠุฑูŠุง ูˆุฃุชู†ุงูˆู„ูู‡ุŒ
10:54
it probably will make me better.
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ุฑุจู…ุง ูŠุฌุนู„ู†ูŠ ุฃูุถู„.
10:55
So I'm trying to do that.
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ุฃู†ุง ุฃุญุงูˆู„ ุฃู† ุฃูุนู„ ุฐู„ูƒ.
10:56
Even though I'm trying this hard,
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ุจุงู„ุฑุบู… ู…ู† ุฃู†ูŠ ุฃุญุงูˆู„ ุฌุงู‡ุฏุงู‹ุŒ
10:59
it's so difficult to test out all possible conditions.
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ุฅู„ุง ุฃู†ู‡ ู…ู† ุงู„ุตุนุจ ุฏุฑุงุณุฉ ูƒู„ ุฃู„ุฃุญูˆุงู„ ุงู„ู…ู…ูƒู†ุฉ.
11:04
It's not possible to do all kinds of experiments at all ...
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ู…ู† ุบูŠุฑ ุงู„ู…ู…ูƒู† ุงู„ุจุชู‘ูŽุฉู ุงุฎุชุจุงุฑ ูƒู„ ุฃู†ูˆุงุน ุงู„ุชุฌุงุฑุจ ..
11:11
but we do have seven billion learning programs on this planet.
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ูˆู„ูƒู† ู„ุฏูŠู†ุง ุณุจุนุฉ ู…ู„ูŠุงุฑ ุจุฑู†ุงู…ุฌู ุชุนู„ูŠู…ูŠู ุนู„ู‰ ู‡ุฐุง ุงู„ูƒูˆูƒุจ.
11:14
Seven billion.
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ุณุจุนุฉ ู…ู„ูŠุงุฑุงุช.
11:16
And every program is running in different conditions
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ูˆู„ูƒู„ ุจุฑู†ุงู…ุฌู ู…ุณุงุฑุงู‹ ุจุธุฑูˆูู ู…ุฎุชู„ูุฉ.
11:19
and doing different experiments.
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ูˆูŠู†ูุฐ ุชุฌุงุฑุจ ู…ุฎุชู„ูุฉ.
11:21
Can we all measure them?
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ู‡ู„ ู†ุณุชุทูŠุน ุฌู…ูŠุนู†ุง ู‚ูŠุงุณู‡ุงุŸ
11:24
Seven years ago, I wrote an essay in "Science"
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ู…ู†ุฐ ุณุจุนุฉ ุณู†ูˆุงุช ูƒุชุจุช ู…ู‚ุงู„ุงู‹ ู„ู…ุฌู„ูŽุฉ "ุงู„ุนู„ูˆู…"
11:28
to celebrate the human genome's 10-year anniversary.
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ู„ู„ุงุญุชูุงู„ ุจู€ ุณู†ูˆูŠุฉ ุฌูŠู†ูˆู… ุงู„ุฅู†ุณุงู† ุงู„ุนุงุดุฑุฉ.
11:31
I said, "Sequence yourself,
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ู‚ู„ุชูุŒ โ€˜ุฅุนู…ู„ ุชุณู„ุณู„ ู„ุฐุงุชูƒโ€˜ุŒ
11:33
for one and for all."
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ู„ูุฑุฏู ูˆุงุญุฏู ูˆู„ู„ุฌู…ูŠุนู.โ€˜
11:35
But now I'm going to say,
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ูˆู„ูƒู†ู†ูŠ ุงู„ุขู† ุณุฃู‚ูˆู„ุŒ
11:37
"Digitalize yourself for one and for all."
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โ€˜ุฅุฌุนู„ู‡ุง ุฑู‚ู…ูŠุฉุŒ ู„ูุฑุฏู ูˆุงุญุฏู ูˆู„ู„ุฌู…ูŠุนู.โ€˜
11:42
When we make this digital me into a digital we,
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ุนู†ุฏู…ุง ู†ุญูˆู„ ุงู„ุดุฎุตูŠุฉ โ€˜ุฃู†ุงโ€˜ ุงู„ุฑู‚ู…ูŠุฉ ุฅู„ู‰ โ€˜ู†ุญู†โ€˜ ุงู„ุฑู‚ู…ูŠุฉุŒ
11:47
when we try to form an internet of life,
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ุนู†ุฏู…ุง ู†ุญุงูˆู„ ุชุดูƒูŠู„ ุดุจูƒุฉู ู„ู„ุญูŠุงุฉุŒ
11:51
when people can learn from each other,
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ุนู†ุฏู…ุง ูŠุชุนู„ู… ุงู„ู†ุงุณ ู…ู† ุจุนุถู‡ู… ุงู„ุจุนุถุŒ
11:54
when people can learn from their experience,
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ุนู†ุฏู…ุง ูŠุชุนู„ู… ุงู„ู†ุงุณ ู…ู† ุชุฌุงุฑุจู‡ู…ุŒ
11:57
their data,
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ู…ู† ู…ุนุทูŠุงุชูู‡ู…ุŒ
11:58
when people can really form a digital me by themselves
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ุนู†ุฏู…ุง ูŠุณุชุทูŠุน ุงู„ู†ุงุณ ุญู‚ุงู‹ ุฃู† ูŠูุดูŽูƒู‘ูู„ูˆุง ุงู„ุดุฎุตูŠุฉ โ€˜ุฃู†ุงโ€˜ ุงู„ุฑู‚ู…ูŠุฉ ุจุฃู†ูุณู‡ู…
12:02
and we learn from it,
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ูˆู†ุชุนู„ู… ู…ู†ู‡ุงุŒ
12:05
the digital we will be totally different with a digital me.
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ุฑู‚ู…ูŠุฉ โ€˜ู†ุญู†โ€˜ ุณุชูƒูˆู† ู…ุฎุชู„ูุฉู‹ ุชู…ุงู…ุงู‹ ุนู† ุฑู‚ู…ูŠุฉ โ€˜ุฃู†ุงโ€˜.
12:10
But it can only come from the digital me.
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ูˆู„ูƒู†ู‡ุง ู„ุง ุชุฃุชูŠ ุฅู„ุง ู…ู† ุฑู‚ู…ูŠุฉ โ€˜ุฃู†ุงโ€˜.
12:15
And this is what I try to propose here.
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ูˆู‡ุฐุง ู…ุง ุฃุญุงูˆู„ ุงู‚ุชุฑุงุญู‡ ู‡ู†ุง.
12:19
Join me --
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ุฅู†ุถู…ูˆุง ู„ูŠ ..
12:21
become we,
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ูƒูˆู†ูˆุง โ€˜ู†ุญู†โ€˜
12:23
and everybody should build up their own digital me,
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ูˆุนู„ู‰ ูƒู„ู ู…ู†ุง ุฃู† ูŠุจู†ูŠ ุฑู‚ู…ูŠุฉ โ€˜ุฃู†ุงโ€˜ ุงู„ุฎุงุตู‘ุฉ ุจู‡ุŒ
12:28
because only by that will you learn more about you,
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ูˆุจู‡ุฐุง ูู‚ุทุŒ ุณู†ุชุนู„ู‘ู… ุฃูƒุซุฑ ุนู†ูƒุŒ
12:33
about me,
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ูˆุนู†ู‘ูŠุŒ
12:34
about us ...
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ูˆุนู†ู‘ุง ุฌู…ูŠุนุงู‹ ..
12:36
about the question I just posed at the very beginning:
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ูˆุนู† ุงู„ุณุคุงู„ ุงู„ุฐูŠ ุทุฑุญุชู‡ ููŠ ุงู„ุจุฏุงูŠุฉ:
12:40
"What is life?"
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ุŒู…ุง ู‡ูŠ ุงู„ุญูŠุงุฉุŸโ€˜
12:41
Thank you.
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ุดูƒุฑุงู‹.
12:43
(Applause)
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(ุชุตููŠู‚)
12:49
Chris Anderson: One quick question for you.
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ูƒุฑูŠุณ ุฃู†ุฏุฑุณูˆู†: ุณุคุงู„ูŒ ุณุฑูŠุนูŒ ู„ูƒ.
12:52
I mean, the work is amazing.
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ุฃุนู†ูŠ ู‡ุฐุง ุนู…ู„ูŒ ุฑุงุฆุน.
12:54
I suspect one question people have is,
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ุฃุนุชู‚ุฏ ุฃู† ู‡ู†ุงูƒ ุณุคุงู„ ูŠุชุจุงุฏุฑ ู„ู†ุงุŒ
12:57
as we look forward to these amazing technical possibilities
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ุนู†ุฏู…ุง ู†ุชุทู„ุน ู„ู„ุฃู…ุงู… ู„ู‡ุฐู‡ ุงู„ุงุญุชู…ุงู„ุงุช ุงู„ุชู‚ู†ูŠุฉ ุงู„ุฑุงุฆุนุฉ
13:01
of personalized medicine,
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ุนู† ุงู„ุทุจ ุงู„ุดุฎุตูŠุŒ
13:02
in the near-term it feels like they're only going to be affordable
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ุนู„ู‰ ุงู„ู…ุฏู‰ ุงู„ู‚ุตูŠุฑ ูŠุจุฏูˆ ุฃู†ู‡ ุณูŠูƒูˆู† ุจู…ู‚ุฏูˆุฑ
13:05
for a few people, right?
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ุนุฏุฏ ู‚ู„ูŠู„ ู…ู† ุงู„ู†ุงุณุŒ ุตุญุŸ
13:07
It costs many dollars to do all the sequencing and so forth.
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ุฅู†ู‡ ูŠูƒู„ู‘ู ุงู„ูƒุซูŠุฑ ู…ู† ุงู„ุฏูˆู„ุงุฑุงุช ู„ุชู‚ูˆู… ุจูƒู„ ุงู„ุชุณู„ุณู„ ูˆู‡ูƒุฐุง.
13:10
Is this going to lead to a kind of,
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ู‡ู„ ุณูŠุคุฏูŠ ู‡ุฐุง ุฅู„ู‰ ู†ูˆุนุŒ
13:13
you know, increasing inequality?
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ู…ุฒูŠุฏุงู‹ ู…ู† ุนุฏู… ุงู„ู…ุณุงูˆุงุฉุŸ
13:15
Or do you have this vision that the knowledge that you get
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ุฃูˆ ู‡ู„ ุนู†ุฏูƒ ุชุตูˆุฑูŒ ุจุฃู† ุงู„ู…ุนุฑูุฉ ุงู„ุชูŠ ุญุตู„ุช ุนู„ูŠู‡ุง
13:19
from the pioneers
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ู…ู† ุงู„ุฑู‘ููˆุงุฏ
13:21
can actually be pretty quickly disseminated
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ูŠู…ูƒู† ูุนู„ุงู‹ ุฃู† ุชู†ุชุดุฑ ุจุณุฑุนุฉ
13:23
to help a broader set of recipients?
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ู„ุชุณุงุนุฏ ู…ุฌู…ูˆุนุฉู ุฃูˆุณุน ู…ู† ุงู„ู…ูุชูŽู„ู‚ูŠู†ุŸ
13:27
Jun Wang: Well, good question.
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ุฌุงู† ูˆุงู†ุบ: ุญุณู†ุงู‹ุŒ ุณุคุงู„ู ุฌูŠุฏ.
13:29
I'll tell you that seven years ago, when I co-founded BGI,
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ุฃู‚ูˆู„ ู„ูƒ ุฃู†ู†ูŠ ู…ู†ุฐ ุณุจุน ุณู†ูŠู† ุนู†ุฏู…ุง ุฃุณุณุช ูˆุดุฑูƒุงุฆูŠ BGI
13:32
and served as the CEO of the company there,
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ูˆุฎุฏู…ุช ูƒู…ุฏูŠุฑ ุชู†ููŠุฐูŠ ุฑุฆูŠุณ ู„ู„ุดุฑูƒุฉุŒ
13:36
the only goal there for me to do
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ูƒุงู† ู‡ุฏููŠ ุงู„ุฑุฆูŠุณูŠ ุฃู†
13:38
was to drive the sequencing cost down.
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ุฃุฎูŽูู‘ูุถ ุชูƒู„ูุฉ ุงู„ุชุณู„ุณู„.
13:40
It started from 100 million dollars per human genome.
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ุงุจุชุฏุฃุช ู…ู† 100 ู…ู„ูŠูˆู† ุฏูˆู„ุงุฑ ู„ ุฌูŠู†ูˆู… ุฅู†ุณุงู†.
13:43
Now, it's a couple hundred dollars for a human genome.
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ุฃู„ุขู† ู‡ูˆ ุจุถุนุฉ ู…ุฆุงุช ู…ู† ุงู„ุฏูˆู„ุงุฑุงุช ู„ ุฌูŠู†ูˆู… ุฅู†ุณุงู†.
13:46
The only reason to do it is to get more people to benefit from it.
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ุงู„ุณุจุจ ุงู„ูˆุญูŠุฏ ู„ุนู…ู„ู‡ ู‡ูˆ ุฃู† ูŠุณุชููŠุฏ ู…ู†ู‡ ุนุฏุฏ ุฃูƒุซุฑ ู…ู† ุงู„ู†ุงุณ.
13:50
So for the digital me, it's the same thing.
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ู„ุฐู„ูƒ ูŠู†ุทุจู‚ ู‡ุฐุง ุนู„ู‰ ุงู„ โ€˜ุงู†ุงโ€˜ ุงู„ุฑู‚ู…ูŠ.
13:52
Now, you probably need,
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ุงู„ุขู†ุŒ ุฑุจู…ุง ุชุญุชุงุฌุŒ
13:53
you know, one million dollars to digitize a person.
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ูƒู…ุง ุชุนู„ู…ุŒ ู…ู„ูŠูˆู† ุฏูˆู„ุงุฑ ู„ุชุฑู‚ูŠู… ุดุฎุต.
13:57
I think it has to be 100 dollars.
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ุฃุนุชู‚ุฏ ุฃู† ู‡ุฐุง ูŠุฌุจ ุฃู† ูŠุตุจุญ 100 ุฏูˆู„ุงุฑ
13:59
It has to be free for many of those people that urgently need that.
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ูŠุฌุจ ุฃู† ูŠูƒูˆู† ู…ุฌุงู†ูŠุงู‹ ู„ู„ูƒุซูŠุฑูŠู† ุงู„ุฐูŠู† ูŠุญุชุงุฌูˆู†ู‡.
14:04
So this is our goal.
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ูˆู‡ุฐุง ู‡ูˆ ู‡ุฏูู†ุง.
14:05
And it seems that with all this merging of the technology,
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ูˆูŠุจุฏูˆ ุฃู†ู‡ ู…ุน ูƒู„ ู‡ุฐู‡ ุงู„ุชู‚ู†ูŠุฉ ุงู„ู†ุงุดุฆุฉุŒ
14:09
I'm thinking that in the very near future,
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ุฃุนุชู‚ุฏ ุฃู†ู‡ ููŠ ุงู„ู‚ุฑูŠุจ ุงู„ุนุงุฌู„ุŒ
14:11
let's say three to five years,
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ู„ู†ู‚ูู„ ุซู„ุงุซ ุงู„ู‰ ุฎู…ุณ ุณู†ูˆุงุชุŒ
14:14
it will come to reality.
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ุณูŠุตุจุญ ูˆุงู‚ุนุงู‹.
14:15
And this is the whole idea of why I founded iCarbonX,
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ูˆู‡ุฐุง ู‡ูˆ ุจุงู„ุถุจุท ู…ุง ุฏูุนู†ูŠ ู„ุชุฃุณูŠุณ iCarbonXุŒ
14:19
my second company.
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ุดุฑูƒุชูŠ ุงู„ุซุงู†ูŠุฉ.
14:21
It's really trying to get the cost down
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ุงู†ู‡ุง ุญู‚ุงู‹ ุชุญุงูˆู„ ุฃู† ุชุฎูุถ ุงู„ุชูƒุงู„ูŠู
14:23
to a level where every individual could have the benefit.
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ู„ู…ุณุชูˆู‰ ูŠู…ูƒู† ู„ูƒู„ ูุฑุฏู ุงู„ุฅุณุชูุงุฏุฉ ู…ู†ู‡.
14:27
CA: All right, so the dream is not elite health services for few,
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ูƒุฑูŠุณ: ุญุณู†ุงู‹ุŒ ุฅุฐุง ูุงู„ุญู„ู… ู„ูŠุณ ุฎุฏู…ุงุช ุตุญูŠุฉู ุฑุงู‚ูŠุฉู ู„ุนุฏุฏู ู…ุญุฏูˆุฏุŒ
14:30
it's to really try
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ุฅู†ู‡ ุฃู† ู†ุญุงูˆู„ ุญู‚ุงู‹
14:31
and actually make overall health care much more cost effective --
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ูˆุฃู† ู†ุฌุนู„ ุชูƒู„ูุฉ ุงู„ุฑุนุงูŠุฉ ุงู„ุตุญูŠุฉ ูุนู‘ุงู„ุฉ ุจุดูƒู„ ุนุงู… ..
14:34
JW: But we started from some early adopters,
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ุฌุงู† ูˆุงู†ุบ: ูˆู„ูƒู†ู†ุง ุจุฏุฃู†ุง ุจุจุนุถ ู…ู† ุชุจู†ู‘ุงู†ุงุŒ
14:37
people believing ideas and so on,
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ูˆุฃู†ุงุณ ุขู…ู†ูˆุง ุจุงู„ููƒุฑุฉ ูˆู‡ูƒุฐุงุŒ
14:39
but eventually, it will become everybody's benefit.
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ูˆู„ูƒู† ุจุงู„ู…ูุญูŽุตู‘ูู„ุฉ ุณูŠูƒูˆู† ู„ู…ุตู„ุฌุฉ ุงู„ุฌู…ูŠุน.
14:44
CA: Well, Jun, I think it's got to be true to say
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ูƒุฑูŠุณ ุฑูˆุจู†ุณูˆู†: ุญุณู†ุงู‹ ุฌุงู†ุŒ ุฃุนุชู‚ุฏ ุฃู†ู‡ ู…ู† ุงู„ุตูˆุงุจ ุงู„ู‚ูˆู„
14:46
you're one of the most amazing scientific minds on the planet,
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ุฃู†ูƒ ูˆุงุญุฏุงู‹ ู…ู† ุฃูƒุซุฑ ุงู„ุนู‚ูˆู„ ุงู„ุนู„ู…ูŠุฉ ุฑูˆุนุฉู‹ ุนู„ู‰ ู‡ุฐุง ุงู„ูƒูˆูƒุจุŒ
14:49
and it's an honor to have you.
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ูˆุฅู†ู‡ ู„ุดุฑู ุฃู† ุชูƒูˆู† ู…ุนู†ุง.
14:50
JW: Thank you.
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ุฌุงู† ูˆุงู†ุบ: ุดูƒุฑุงู‹.
14:52
(Applause)
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(ุชุตููŠู‚)
ุญูˆู„ ู‡ุฐุง ุงู„ู…ูˆู‚ุน

ุณูŠู‚ุฏู… ู„ูƒ ู‡ุฐุง ุงู„ู…ูˆู‚ุน ู…ู‚ุงุทุน ููŠุฏูŠูˆ YouTube ุงู„ู…ููŠุฏุฉ ู„ุชุนู„ู… ุงู„ู„ุบุฉ ุงู„ุฅู†ุฌู„ูŠุฒูŠุฉ. ุณุชุฑู‰ ุฏุฑูˆุณ ุงู„ู„ุบุฉ ุงู„ุฅู†ุฌู„ูŠุฒูŠุฉ ุงู„ุชูŠ ูŠุชู… ุชุฏุฑูŠุณู‡ุง ู…ู† ู‚ุจู„ ู…ุฏุฑุณูŠู† ู…ู† ุงู„ุฏุฑุฌุฉ ุงู„ุฃูˆู„ู‰ ู…ู† ุฌู…ูŠุน ุฃู†ุญุงุก ุงู„ุนุงู„ู…. ุงู†ู‚ุฑ ู†ู‚ุฑู‹ุง ู…ุฒุฏูˆุฌู‹ุง ููˆู‚ ุงู„ุชุฑุฌู…ุฉ ุงู„ุฅู†ุฌู„ูŠุฒูŠุฉ ุงู„ู…ุนุฑูˆุถุฉ ุนู„ู‰ ูƒู„ ุตูุญุฉ ููŠุฏูŠูˆ ู„ุชุดุบูŠู„ ุงู„ููŠุฏูŠูˆ ู…ู† ู‡ู†ุงูƒ. ูŠุชู… ุชู…ุฑูŠุฑ ุงู„ุชุฑุฌู…ุงุช ุจุงู„ุชุฒุงู…ู† ู…ุน ุชุดุบูŠู„ ุงู„ููŠุฏูŠูˆ. ุฅุฐุง ูƒุงู† ู„ุฏูŠูƒ ุฃูŠ ุชุนู„ูŠู‚ุงุช ุฃูˆ ุทู„ุจุงุช ุŒ ูŠุฑุฌู‰ ุงู„ุงุชุตุงู„ ุจู†ุง ุจุงุณุชุฎุฏุงู… ู†ู…ูˆุฐุฌ ุงู„ุงุชุตุงู„ ู‡ุฐุง.

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