Is DNA the future of data storage? - Leo Bear-McGuinness

396,162 views ・ 2017-10-09

TED-Ed


Please double-click on the English subtitles below to play the video.

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Let's say there's a disaster that sends humanity back to the Stone Age.
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Can our knowledge and history survive?
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The printed page will decompose.
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Hard drive storage will deteriorate.
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Even stones will eventually crumble.
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But we might have something inside us that can outlast these physical limitations:
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deoxyribonucleic acid.
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DNA already stores our biological information.
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From eye color to skin tone, it programs our entire bodies.
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DNA is made of four organic bases:
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adenine,
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guanine,
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cytosine,
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and thymine,
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or A, G, C, and T.
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The specific sequence of these bases into groups of three, known as codons,
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gives our cells instructions to make each of the proteins in our bodies.
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But this code can be used for other things, too,
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like secret messages.
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In 1999, scientists in New York created an alphabet
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in which each of the 64 possible DNA codons
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substituted for a specific letter, number, or grammar symbol.
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They spliced a 22-character message into a long strand of DNA
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and surrounded it with specific genetic markers.
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They then hid the DNA over a period in a type-written letter
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with only a small smudge to give the location away.
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They mailed the letter back to themselves.
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Then they examined the letter looking for the DNA strand.
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Once the DNA strand was located, they found the genetic markers.
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Then, they sequenced the DNA and successfully decoded the message.
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It soon became obvious that DNA cryptography
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could code for much more than simple text.
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By translating the 1's and 0's of binary code into DNA codons,
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digital data could be programmed into synthetic DNA,
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then decoded back into its original form.
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In 2012, UK scientists encoded 739 kilobytes of computer files
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into DNA strands,
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including all 154 Shakespeare sonnets
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and an excerpt from Martin Luther King's "I Have a Dream" speech.
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And four years later, researchers at Microsoft and the University of Washington
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broke that record.
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They used binary coding to capture a whopping 200 megabytes of data,
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including the Universal Declaration of Human Rights
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and a high-def OK Go music video,
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all in strings of DNA.
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As far as storage capacity goes,
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DNA stands out because of the surprising amount of information it can hold
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in so little space.
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The current theoretical limit of DNA'S storage capacity is so high
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that you could fit 100 million HD movies on a pencil eraser.
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It's even conceivable that one day we could fit all of the information
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currently on the Internet
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into the space of a shoe box.
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Also, computers and the magnetic tape and discs that their information is stored on
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only last for a few decades, at most, before degrading and becoming unreliable.
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Meanwhile, DNA has a half-life of 500 years,
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meaning that's how long it takes for half of its bonds to break.
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And if left in a cold and dark environment,
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DNA could potentially last for hundreds of thousands of years.
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And if that isn't long enough,
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scientists experimented with having synthetic DNA auto-reproduce.
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After creating their own strands of DNA
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that spelled out the lyrics to the children's song "It's a Small World,"
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they placed them into the genome of a microbe nicknamed Conan the Bacterium.
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Conan belongs to a species which can survive in a vacuum,
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or without water, for six years,
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or come out unscathed after being exposed to a dose of radiation
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1,000 times that which would kill a human.
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According to the experiment,
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the bacterium was able to reproduce at least 100 generations without data loss.
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Theoretically, if the organism had redundant copies of the information
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that could be used to automatically correct mistakes,
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the information could stay preserved even longer.
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So one day, you might be able to create a living, growing, knowledge archive
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in your own backyard,
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and its seeds might carry your family's history,
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a detailed breakdown of the world's political upheavals,
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or the sum of humanity's knowledge into forests and across continents.
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Perhaps even into the far reaches of space.
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Though we might one day disappear, perhaps our legacy can still live on,
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if anyone would think to find it.
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