Is DNA the future of data storage? - Leo Bear-McGuinness

394,855 views ・ 2017-10-09

TED-Ed


Please double-click on the English subtitles below to play the video.

00:07
Let's say there's a disaster that sends humanity back to the Stone Age.
0
7183
5143
00:12
Can our knowledge and history survive?
1
12326
3078
00:15
The printed page will decompose.
2
15404
2009
00:17
Hard drive storage will deteriorate.
3
17413
2341
00:19
Even stones will eventually crumble.
4
19754
3140
00:22
But we might have something inside us that can outlast these physical limitations:
5
22894
5360
00:28
deoxyribonucleic acid.
6
28254
2630
00:30
DNA already stores our biological information.
7
30884
3850
00:34
From eye color to skin tone, it programs our entire bodies.
8
34734
5120
00:39
DNA is made of four organic bases:
9
39854
2900
00:42
adenine,
10
42754
911
00:43
guanine,
11
43665
724
00:44
cytosine,
12
44389
806
00:45
and thymine,
13
45195
1371
00:46
or A, G, C, and T.
14
46566
2800
00:49
The specific sequence of these bases into groups of three, known as codons,
15
49366
4719
00:54
gives our cells instructions to make each of the proteins in our bodies.
16
54085
5460
00:59
But this code can be used for other things, too,
17
59545
2940
01:02
like secret messages.
18
62485
2251
01:04
In 1999, scientists in New York created an alphabet
19
64736
3960
01:08
in which each of the 64 possible DNA codons
20
68696
3940
01:12
substituted for a specific letter, number, or grammar symbol.
21
72636
5511
01:18
They spliced a 22-character message into a long strand of DNA
22
78147
5139
01:23
and surrounded it with specific genetic markers.
23
83286
3720
01:27
They then hid the DNA over a period in a type-written letter
24
87006
4621
01:31
with only a small smudge to give the location away.
25
91627
4120
01:35
They mailed the letter back to themselves.
26
95747
2330
01:38
Then they examined the letter looking for the DNA strand.
27
98077
3601
01:41
Once the DNA strand was located, they found the genetic markers.
28
101678
3879
01:45
Then, they sequenced the DNA and successfully decoded the message.
29
105557
4842
01:50
It soon became obvious that DNA cryptography
30
110399
2688
01:53
could code for much more than simple text.
31
113087
3791
01:56
By translating the 1's and 0's of binary code into DNA codons,
32
116878
4741
02:01
digital data could be programmed into synthetic DNA,
33
121619
3999
02:05
then decoded back into its original form.
34
125618
3843
02:09
In 2012, UK scientists encoded 739 kilobytes of computer files
35
129461
5697
02:15
into DNA strands,
36
135158
2218
02:17
including all 154 Shakespeare sonnets
37
137376
3631
02:21
and an excerpt from Martin Luther King's "I Have a Dream" speech.
38
141007
4012
02:25
And four years later, researchers at Microsoft and the University of Washington
39
145019
4660
02:29
broke that record.
40
149679
2401
02:32
They used binary coding to capture a whopping 200 megabytes of data,
41
152080
5510
02:37
including the Universal Declaration of Human Rights
42
157590
2911
02:40
and a high-def OK Go music video,
43
160501
3169
02:43
all in strings of DNA.
44
163670
2700
02:46
As far as storage capacity goes,
45
166370
2581
02:48
DNA stands out because of the surprising amount of information it can hold
46
168951
4409
02:53
in so little space.
47
173360
2281
02:55
The current theoretical limit of DNA'S storage capacity is so high
48
175641
4150
02:59
that you could fit 100 million HD movies on a pencil eraser.
49
179791
5450
03:05
It's even conceivable that one day we could fit all of the information
50
185241
4081
03:09
currently on the Internet
51
189322
1479
03:10
into the space of a shoe box.
52
190801
2921
03:13
Also, computers and the magnetic tape and discs that their information is stored on
53
193722
5169
03:18
only last for a few decades, at most, before degrading and becoming unreliable.
54
198891
7129
03:26
Meanwhile, DNA has a half-life of 500 years,
55
206020
4433
03:30
meaning that's how long it takes for half of its bonds to break.
56
210453
4220
03:34
And if left in a cold and dark environment,
57
214673
3220
03:37
DNA could potentially last for hundreds of thousands of years.
58
217893
5428
03:43
And if that isn't long enough,
59
223321
1603
03:44
scientists experimented with having synthetic DNA auto-reproduce.
60
224924
5829
03:50
After creating their own strands of DNA
61
230753
2360
03:53
that spelled out the lyrics to the children's song "It's a Small World,"
62
233113
3741
03:56
they placed them into the genome of a microbe nicknamed Conan the Bacterium.
63
236854
5836
04:02
Conan belongs to a species which can survive in a vacuum,
64
242690
4104
04:06
or without water, for six years,
65
246794
2600
04:09
or come out unscathed after being exposed to a dose of radiation
66
249394
4780
04:14
1,000 times that which would kill a human.
67
254174
4689
04:18
According to the experiment,
68
258863
1251
04:20
the bacterium was able to reproduce at least 100 generations without data loss.
69
260114
6900
04:27
Theoretically, if the organism had redundant copies of the information
70
267014
4300
04:31
that could be used to automatically correct mistakes,
71
271314
3011
04:34
the information could stay preserved even longer.
72
274325
4561
04:38
So one day, you might be able to create a living, growing, knowledge archive
73
278886
5069
04:43
in your own backyard,
74
283955
2350
04:46
and its seeds might carry your family's history,
75
286305
2701
04:49
a detailed breakdown of the world's political upheavals,
76
289006
3469
04:52
or the sum of humanity's knowledge into forests and across continents.
77
292475
6172
04:58
Perhaps even into the far reaches of space.
78
298647
3700
05:02
Though we might one day disappear, perhaps our legacy can still live on,
79
302347
4421
05:06
if anyone would think to find it.
80
306768
2659
About this website

This site will introduce you to YouTube videos that are useful for learning English. You will see English lessons taught by top-notch teachers from around the world. Double-click on the English subtitles displayed on each video page to play the video from there. The subtitles scroll in sync with the video playback. If you have any comments or requests, please contact us using this contact form.

https://forms.gle/WvT1wiN1qDtmnspy7