What does appendix pain feel like? - David R. Flum

477,024 views ・ 2024-09-05

TED-Ed


Please double-click on the English subtitles below to play the video.

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In April 1961, the Sixth Soviet Antarctic Expedition took a harrowing turn.
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Doctor Leonid Rogozov, the team’s only physician,
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began feeling weak and feverish,
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with an excruciating pain in his right side.
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After a few days, it became clear that he had appendicitis,
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an infection that can cause the appendix to burst.
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And Rogozov knew that if his appendix did rupture,
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it would likely kill him.
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Outside a blizzard raged,
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making it dangerous for him to leave the station,
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or to have anyone else travel in.
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So Rogozov faced a gut-wrenching choice: wait for help that may never come,
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or cut open his own abdomen and remove the appendix himself.
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While Rogozov’s predicament may have been extreme,
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appendicitis is not uncommon.
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It affects roughly 1 in 12 people.
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So, what causes appendicitis?
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And why is this organ so prone to bursting?
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The appendix is a small, worm-shaped pouch attached to the large intestine
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that houses a diversity of gut microbes.
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Scientists long speculated that it was a useless artifact of evolution.
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Recent evidence shows that this organ independently evolved
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in many different mammals.
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This suggests that it probably has some function,
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though it's likely subtle.
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One possibility is that the appendix serves as a reservoir
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for healthy gut bacteria,
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or it may play a role in mounting immune responses.
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What we do know is this puzzling organ can cause serious complications.
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Most cases of appendicitis start with some sort of obstruction.
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For example, a small, dried piece of stool,
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called an appendicolith,
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can lodge itself in the organ’s entrance.
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Other times, pathogens like viruses or parasites activate the immune system,
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causing inflammation.
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This immune response may even be triggered
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by one of hundreds of species of bacteria
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that normally reside in your gut.
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As a result, nearby lymph nodes swell,
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effectively closing off the appendix’s opening.
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Because the appendix is a closed loop, when it's sealed, pressure builds quickly.
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This creates the perfect environment for bacteria to colonize and overgrow.
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As the inflamed appendix bloats, discomfort sets in.
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And this pain is different from your everyday stomach ache.
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It typically starts near the belly button
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and then migrates to the lower right abdomen and intensifies.
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If left untreated, the appendix can continue to stretch,
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hindering blood flow and weakening the organ walls.
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Eventually, this can cause the appendix to rupture,
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allowing the infection to spread within the abdomen,
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where it can pose fatal consequences.
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Thankfully, not all cases of appendicitis will lead to a rupture,
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but it's impossible to know exactly when or if
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the appendix will burst from symptoms alone.
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So, it’s recommended that all people with severe abdominal pain
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seek immediate medical attention.
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Since doctors first identified appendicitis in the late 1800s,
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an appendectomy, or the surgical removal of the appendix,
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has been the standard treatment.
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It’s normally performed quickly, within 24 hours of diagnosis.
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Doctors remove the inflamed organ, which can double in size,
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either through one large incision,
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or through several smaller incisions using a camera and small instruments.
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Recovery is typically quick,
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and most patients are discharged within a day or two.
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Though, if the appendix has burst, surgery can be more extensive
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as any bacteria and pus need to be thoroughly cleaned
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from the abdominal cavity.
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In the long term, living without an appendix
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is unlikely to lead to any health issues.
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Today, thanks to medical advances, many patients avoid surgery altogether.
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Doctors have learned that appendicitis can often be treated
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with a simple course of antibiotics,
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started in the emergency room and continued at home.
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No matter the chosen course of treatment,
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it’s likely to be less distressing than Rogozov’s,
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who, after giving himself local anesthesia,
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removed his own appendix, stitched himself up,
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and resumed his regular duties just two weeks later.
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Nevertheless, thanks to his story,
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doctors on remote stations in Antarctica now know to bring plenty of antibiotics
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to treat appendicitis,
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just in case.
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