How You Could See Inside Your Body — With a Micro-Robot | Alex Luebke and Vivek Kumbhari | TED

28,205 views ・ 2024-06-26

TED


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00:04
Alex Luebke: I'd like to invite you to go on a fantastic voyage with me today,
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as we explore inside the human body.
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Inside each and every one of us holds mysteries and wonders
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that if unlocked, lead to better health, performance and longevity.
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But seeing inside has proven to be quite difficult.
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Since the beginning of the modern era,
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the only way to really look inside was through rudimentary surgeries.
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Over the past 150 years or so,
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we've had great technologies that allow us to look from the outside,
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like X-rays and MRIs.
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But what I propose and what I'd like us to explore today
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is looking at microrobotics inside the human body.
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As a first step on that journey, let me introduce you to PillBot.
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PillBot is a small, wireless robot that is remotely controlled,
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and it swims around in three dimensions in a water-filled human stomach.
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This robot has things you would expect on a robot.
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It has a camera, so it gives you a live video feed.
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It has control circuitry.
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It has LED lights because inside the human body it's quite dark.
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It has a wireless data link and it has a battery.
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Now the way this robot moves is it has three pump jet thrusters
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that squirt water in six different directions,
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that allow the pilot to fly around in three-dimensional space
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in a water volume.
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Over the past five years, we've spent a lot of time
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to get the size of this robot smaller and smaller.
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What we started with wasn't quite --
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(Laughter)
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Not quite swallowable.
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But we finally worked our way down
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and where we are these days
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is about the size of a small multivitamin capsule.
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(Applause)
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Thank you.
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Now we're going to fly this robot around for you for a little bit.
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But to do that, I would like to invite Doctor Vivek Kumbhari.
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He's the chairman of gastroenterology at the Mayo Clinic.
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And I'd like to have him pilot this PillBot while I turn it on.
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(Applause)
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Vivek Kumbhari: Here is a common scenario I encounter in my clinic.
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A patient who's generally in good health
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comes to see me because they have abdominal pain,
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and I suspect it's coming from the stomach.
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Now I need to understand precisely what the problem is,
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but I can't just pop my head in and take a look.
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So, and despite that patient sitting right in front of me,
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I need to ask them to go back home
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and come back to the hospital on another occasion
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so I can put them to sleep with anesthesia
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so that they allow me to insert this long tube with a camera at the tip,
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through the mouth and into the stomach.
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This is an endoscopy,
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and it's a relatively invasive and expensive procedure,
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and we are on a mission to do better.
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We'd like to transform this experience
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by dematerializing the physical hospital into PillBot.
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As you can see here, we have a capsule here,
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and I'm using a game controller to navigate PillBot.
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Although I could have also used a tablet or a smartphone.
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You can move it around rather quickly here,
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and you can imagine that using the tank this size,
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we're still able to navigate the entire experience,
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which -- and this tank is significantly larger
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than the human stomach,
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or any internal human organ for that matter.
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I'm going to pause here while Alex is working on optimizing the robot.
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AL: There we go.
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(Laughter)
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VK: So this is our goal. Be anywhere in the world.
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Whether you're at home, sitting on your couch,
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visiting space, or right here onstage at TED.
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What do you think, Alex? You should go ahead and swallow a PillBot?
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(Applause and cheers)
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So, as you can see, in just a few seconds, PillBot entered the stomach.
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So we're in the stomach now,
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and I'm carefully navigating around,
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looking for any changes in surface architecture
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that might represent an ulcer or a cancer, or any other pathology.
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And I'm able to get very similar views
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as I would if I'd used a conventional endoscope.
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Now I'm able to see the entire stomach
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and revisit sites that piqued my curiosity.
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And what could further improve this experience
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is if we used an augmented reality headset for 3D visualization of a stomach,
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or artificial intelligence for detection and characterization of an abnormality.
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Now, fortunately for Alex,
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on this brief review, everything is looking normal here.
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(Laughter and applause)
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Though if there were a problem,
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being able to show and discuss with Alex in real time
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elevates his understanding of his health
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and is going to make him more compliant with therapy.
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So now that we're done here,
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PillBot will take its natural course through and out the body.
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(Laughter)
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And fortunately for Alex, he'll have no awareness of this,
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and he won't have to retrieve this capsule.
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(Laughter)
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Now this robot was designed for the stomach,
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though the entire body needs this capability.
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Parts of the body, such as the colon, the heart and the brain
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should be made accessible with specialized robots
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that are just as easy to use.
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I've dreamt of the day
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when I could explore the inside of the human body with robots,
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recognizing it would be an inflection point
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in my ability to help people live longer and healthier lives.
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Back to you, Alex.
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(Applause)
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AL: That was yummy.
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(Laughter)
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And no, you don't feel anything when the robot moves around inside you.
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It's quite, quite simple.
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But think of that.
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How easy it was to get access to internal imagery anywhere.
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So that's going to allow us not only internal imagery,
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but also the diagnosis and the treatment that the doctor might be able to give.
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That's going to give us access to a vast amount of information
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that we can then use to train AI.
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And with AI, we're going to be able
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to have it automate a whole variety of different functions,
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from performance improvement of the robot itself
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to autonomous control,
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where it actually flies around and maps out the entire interior surface
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of the stomach all on its own.
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That diagnosis and the treatment also comes along with that.
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And we train AI to help learn how to do that.
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And eventually, interventions.
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Let's talk about a little bit where we want to go next.
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So the first thing we're going to do, we'll add some accelerometers on there,
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so it actually helps with that autonomous control.
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Also very interesting, we can start adding different sensors.
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So wherever the robot is going,
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we can go ahead and measure the health of what it's looking at right there.
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And as far as doing lab-on-chip capabilities
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where you can actually analyze the material
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right there in situ on the robot.
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Imagine now being able to put different tools onto this,
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where you can cut and you can cauterize
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or inject medicine.
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Well, now you have a pill surgeon.
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And of course, you can have clusters of these robots
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that work together in unison
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to do complex procedures inside the human body.
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To go even smaller, we actually have technology that exists today
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that allows us to make robots at the nanoscale,
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which now can bring robots anywhere in the human body,
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even into the human brain.
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And there's some phenomenal power sources that are available,
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coming online as well.
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While PillBot is just about to go through clinical trials,
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it'll be a couple of years till it's on the market.
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There's a long way to go we still have
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to bring the full ability to do inner space exploration on us all.
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But it's a worthwhile journey to go on.
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Imagine being able to have all this information for you,
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for your health, for your family and for humanity.
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So I'd like to invite all of you to join us in being brave.
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And let's bring microrobots inside the human body.
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Thank you very much.
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(Applause and cheers)
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