Can I have your brain? The quest for truth on concussions and CTE | Chris Nowinski

64,448 views ・ 2018-04-11

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I'm Chris Nowinski, and odds are if you've met me in the last five years
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I've asked you, after a few minutes, a bit of an odd question:
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Can I have your brain?
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Now, it only seems like a strange question if you don't know my story
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so please let me share it with you.
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I grew up outside of Chicago, and I was an athlete
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and I was very lucky to get recruited to play football at Harvard University.
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So that's me.
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And then after graduating, like most Harvard graduates,
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I decided I wanted to join the WWE.
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So that's also me.
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(Laughter)
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Sure you remember me from Monday Night Raw in 2002 and 2003,
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and I had a blast
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playing what people affectionately like to call
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Chris Harvard, the Ivy League snob.
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(Laughter)
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It was perfect for me.
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But unfortunately,
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I got kicked in the head by my colleague Bubba Ray Dudley,
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and I suffered a severe concussion.
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And it led to what became permanent postconcussion symptoms:
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constant headaches, inability to sleep, depression, feeling in a fog.
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And in that first year,
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I tried to figure out how could I make this pain go away.
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And I wasn't getting the answers I needed from doctors,
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and so I started digging into the medical literature.
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And I found there's this whole story about concussions
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that we weren't really being told.
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So I decided to write a book about it,
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called "Head Games: Football's Concussion Crisis"
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that came out in 2006.
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But in that process, I learned it's not really just about concussions.
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I learned about a disease called chronic traumatic encephalopathy or CTE.
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What we used to call punch-drunk, because we only knew about it from boxers.
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We knew that getting hit in the head too many times with boxers
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would cause their brain to essentially start to rot, to degenerate.
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And they'd have symptoms
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like memory problems and problems with cognition,
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depression, impulse control issues, aggression.
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So basically, I got ...
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I got injured at the right time,
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in which the first two NFL players were studied for this disease.
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And it turned out they both had it.
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The first was Mike Webster, 50 years old, already had dementia.
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The second, Terry Long, 45 years old when he took his life.
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The medical examiner in Pittsburgh decided to look at their brains
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and found this disease.
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I wrote a chapter about it,
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and I thought people would make a big deal out of it.
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But shockingly, even when the first two cases came in positive,
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there was never a national news story about this,
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what's going on in football with these cases of CTE.
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So the book comes out,
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not a whole lot is happening,
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and one day I read the newspaper -- November 20, 2006.
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I find out that Andre Waters just took his life.
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Those of you who know football,
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Andre Waters was someone I grew up watching.
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Former Philadelphia Eagles strong safety,
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[44] years old, a Division II football coach
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when he decided to put a gun to his head.
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In the article they reminded me, his nickname was Dirty Waters.
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He was known for leading with his head,
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so I thought I'm just going to look up
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did he ever talk about the concussions he had.
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And I found a quote from 1994 where Andre Waters said,
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"I stopped counting my concussions at 15.
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I wouldn't say anything, I'd just sniff smelling salts and go back out there."
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And I thought, I wonder if he might have CTE, too.
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If that might have contributed to whatever made him choose to end his life.
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So I ended up calling the doctor who did the first two studies, and I said,
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"Hey, I think you should study Andre Waters."
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And he said, "I'd be happy to.
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The problem is, the first two cases died in the county in which I work,
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and I could study them as part of my job.
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I can't do that with Andre Waters, he died in Florida.
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If you want me to study him, you're going to have to figure out
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how to get me the brain."
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So I said, "OK.
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How does one get a brain?"
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(Laughter)
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So I racked my brain
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and I thought, why don't I call the medical examiner
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who I think has the brain right now?
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So I called up the medical examiner in Florida, and I said,
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"Hey, you don't know me, but do you still have the brain of Andre Waters?"
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(Laughter)
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And he said, "Yes, I do."
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I said, "OK, are you going to study him for CTE?"
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And he said no, in fact at that time he didn't believe that was a real disease.
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I said, "OK, if you're not, do you mind if I have it?"
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And he said, "Well, young man,
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I can't give you the brain.
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You need his family's permission.
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But if you do get the permission of his next of kin,
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I will release the brain to you."
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And I said, "Great!"
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And then I realized I had to figure out who his next of kin was and ask them,
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and it turned out it was Andre Waters's 88-year-old mother.
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And I sat there, and I took a breath and I thought,
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"Am I really going to cold-call an 88-year-old grieving mother
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who just lost her son to suicide?"
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And almost everything in me said, "Don't do it.
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It's too much to put this poor woman through,
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she's been through so much already."
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But then this other voice in my head said,
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"You know what?
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If guys are killing themselves from this disease
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and we could study it to maybe prevent this from happening in the future,
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sometimes you've just got to suck it up and do something that's very hard."
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So I called her.
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First time, nobody answered.
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Second time, no one answered, third... no voice mails.
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The fifth time, I got an answer.
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And thank God that Andre Waters's family was so gracious about the call and said,
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"You know what, we want to know what happened to Andre.
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We want to know why he changed so much in the last five years of his life."
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And so we studied the brain,
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and it turned out that he did have CTE.
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He became the third NFL player diagnosed with the disease.
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This is what it looks like.
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He was somewhere between mild and severe.
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OK, we have three of three NFL players here.
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Maybe this needs to get a little bit more serious.
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Maybe something's happening here.
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So I ended up starting the Concussion Legacy Foundation,
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actually formalized the work,
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so it wasn't just some guy calling for brains.
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And I searched the world.
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And I put together the best research team I could find.
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So we partnered with Boston University,
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we partnered with scientists at the VA here in Boston,
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and we started a brain bank.
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Turns out, if you want to know how to cure degenerative brain disease,
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you have to start by actually studying the brains.
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At this point, we were the first center in the world focused on CTE.
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It just had not been studied formally.
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And so we start this brain bank, and it's my job to get the brains
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for Dr. Ann McKee and her brain bank, right in the middle.
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We also work with Dr. Bob Stern, Dr. Robert Cantu,
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truly my dream team of scientists that I support.
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So my job is to get the brains.
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And I was very successful in those early years.
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Since 2007 I've started every day by reading the obituaries.
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And it's a tough way to live.
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And it's hard on me
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and it's even worse on these poor families that I've been calling
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for the last 10 years, to ask for their brains.
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And so early on in the process, as it started to really eat away at me,
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I decided, you know what, can I find another way
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to get people to donate their brains to this research?
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And I figured out, what if we could create a culture
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of brain donation in this country?
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What if it became normal for athletes to donate their brain after they died?
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And so what I started was a brain donation registry.
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And I started asking athletes
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if they would publicly pledge to donate their brain to science.
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And it started with, actually, a hockey player in 2009.
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One of my first pledges was a former Harvard hockey player,
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Noah Welch, who was in the NHL at the time.
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It was a slow start people understanding what this was about.
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So when the news hit the front page,
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"Noah Welch pledging his brain to science,"
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he said he went to the locker room the next day,
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one of his teammates pulled him aside and said,
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"Hey, I heard you're donating your brain to science."
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And he said, "Yep."
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And he said, "Wow. How many games are you going to miss?"
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(Laughter)
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True story.
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(Laughter)
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But we've been remarkably successful --
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over 2,500 athletes have signed up.
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They get a brain-donation card they keep in their wallet.
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This is mine, I was obviously first, it says 01.
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And I will donate my brain to this.
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We've also been lucky to have people like Brandi Chastain,
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the women's soccer icon,
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NASCAR's Dale Earnhardt Jr.
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Just two weeks ago, Hall-of-Famer Nick Buoniconti
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who had been diagnosed with dementia, signed up to pledge his brain.
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So it's been wonderful, and the great thing about it
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is that it has worked in changing how we're able to get brains.
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So now, instead of me having to call, more families call us.
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And our phones ring off the hook.
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And so I can now focus on taking this information,
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figuring out how do we work towards a cure,
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how do we work towards prevention,
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and so my life has gotten a lot easier.
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This is just some of the headlines that we've able to get over the years
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from athletes pledging their brain.
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The problem has been what we learned.
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So when we started this,
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only 45 cases existed in the world of this disease
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that had been studied in brain banks.
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Since then, we have acquired 500 brains
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and found over 300 of them had CTE.
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To put that in perspective,
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the rest of the world has not studied 100 brains since we started this.
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What we've seen though is very frightening.
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So some of you might have seen the headline in July
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in the "New York Times."
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And a recent study we published,
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that of the first 111 NFL players we looked at
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110 were positive for this disease.
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Of the first 53 college football players we looked at,
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48 had this disease.
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That's something that's a very big concern to me.
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And so now, I'm very much focused
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on what can we do to actually treat this disease?
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We still can't diagnose CTE in living people,
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we have no treatments that are going to be coming
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out of the pharmaceutical industry in the next five years.
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This is a long, long fight.
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But our Concussion Legacy Foundation is here to not only facilitate this work,
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and that's the long game,
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but the short game is, hey, we can prevent this.
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We can prevent this disease
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if we just stopped hitting people in the head so much.
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And frankly, we need to stop hitting children in the head.
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Turns out, it's not a great idea to hit a five-year-old in the head
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500 times each year.
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And it does actually open up the door to this disease.
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And so, we've got a lot of work ahead of us.
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But I have great hope that we're on our way to curing this disease.
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But I hope you understand my story a little more now.
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And now that we've gotten to know each other a little bit better,
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this is the time where I ask you,
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"Can I have your brain?"
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Thank you very much.
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(Applause)
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Thank you.
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(Applause)
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